PBYI

PUMA BIOTECHNOLOGY, INC.

Nasdaq · Pharmaceutical Preparations · Inc. DE · CIK 0001401667
$7.01 -0.50% $358.8M
Vol
Market Cap$358.8M
Cap SizeSmall Cap
Inst. Holders9 funds
Inst. Value$40.5M
Inst. Activity2 buys / 0 sells
Reddit Sentiment50° Neutral
SEC Reports1
Exchange Nasdaq·Sector Pharmaceutical Preparations·Inc. DE·CIK 0001401667·Prev Close $7.05

Recent Activity

May 7, 2026 earnings_calendar
PBYI Q1 2026 Earnings Scheduled — 2026-05-07
Feb 26, 2026 SEC
Puma Biotechnology reported fourth quarter and full year 2025 financial results with product revenue growth to $204.1 mi
8-K — Impact 6/10
Feb 18, 2026 Insider
AUERBACH ALAN H sold 159,778 shares
President and CEO @ $0.00 ($0.00)
Feb 18, 2026 Insider
AUERBACH ALAN H sold 227,474 shares
President and CEO @ $0.00 ($0.00)
Feb 18, 2026 Insider
HUNT DOUGLAS M sold 49,394 shares
See Remarks @ $0.00 ($0.00)
Inst.
TWO SIGMA INVESTMENTS, LP — DOUBLED
162,351 shares ($966.0K)
Inst.
WELLS FARGO & COMPANY/MN — ADD
48,281 shares ($287.3K)

Price Targets

Historical data — last covering-analyst action Feb 2025. No current recommendation available.
$5.00 (Feb 2025)
Current $7.02 Low $5.00 Median $5.00 High $5.00 1 analysts
$5.00 $5.00

Analyst Ratings

Historical distribution0% buy · 6 analysts · last covering-analyst action Feb 2025
0Strong Buy
0Buy
3Hold
1Sell
2Strong Sell
Historical Analyst Actions
DateFirmActionRating
Feb 28, 2025 HC Wainwright & Co. REITERATE Buy → Buy
Dec 23, 2024 HC Wainwright & Co. REITERATE Buy → Buy
Nov 20, 2024 HC Wainwright & Co. REITERATE Buy → Buy
Nov 8, 2024 HC Wainwright & Co. REITERATE Buy → Buy
Aug 2, 2024 HC Wainwright & Co. REITERATE Buy → Buy

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $0.07 $0.07 — $0.07 -53% YoY 1
Next Q $0.19 ▼ -9.5% $0.19 — $0.19 -10% YoY 1
Current FY $0.45 ▲ +12.5% $0.45 — $0.45 -40% YoY 1
Next FY $0.35 ▼ -46.2% $0.35 — $0.35 -22% YoY 1

Top Institutional Holders

FundValueMove
VANGUARD GROUP INC$22.6M
RENAISSANCE TECHNOLOGIES LLC$12.6M
MORGAN STANLEY$1.9M
FMR LLC$975.0K
TWO SIGMA INVESTMENTS, LP$966.0KDOUBLED

Recent Insider Trades

DateInsiderTypeValue
Feb 18, 2026AUERBACH ALANA$0.00
Feb 18, 2026AUERBACH ALANA$0.00
Feb 18, 2026HUNT DOUGLASA$0.00
Feb 18, 2026HUNT DOUGLASA$0.00
Feb 18, 2026NOUGUES MAXIMOA$0.00

Reddit Sentiment

50°
Neutral
Bearish Neutral Bullish
1 mentions 0 bullish 0 bearish
9 institutional holders with $40.5M total value (6,813,904 shares) as of 2025-Q4. Top holders: VANGUARD, RENAISSANCE, MORGAN. Net buying activity: 2 institutions added/increased vs 0 reduced.

Top Institutional Holders — 2025-Q4

#FundSharesValue% of TrackedLast Move
1VANGUARD GROUP INC3,797,748$22.6M55.7%
2RENAISSANCE TECHNOLOGIES LLC2,123,813$12.6M31.2%
3MORGAN STANLEY326,774$1.9M4.8%
4FMR LLC163,870$975.0K2.4%
5TWO SIGMA INVESTMENTS, LP162,351$966.0K2.4%DOUBLED +189.3%
6CHARLES SCHWAB INVESTMENT MANAGEMENT INC125,372$746.0K1.8%NEW
7BANK OF AMERICA CORP /DE/52,385$311.7K0.8%TRIM -33.1%
8WELLS FARGO & COMPANY/MN48,281$287.3K0.7%ADD +48.4%
9CAUSEWAY CAPITAL MANAGEMENT LLC13,310$79.2K0.2%NEW

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
TWO SIGMA INVESTMENTS, LPDOUBLED56,126162,351+189.3%$966.0K2025-Q4
WELLS FARGO & COMPANY/MNADD32,53148,281+48.4%$287.3K2025-Q4
UBS Group AGADD274,100376,091+37.2%$2.0M2025-Q3
TWO SIGMA INVESTMENTS, LPTRIM190,62156,126-70.6%$298.0K2025-Q3
BANK OF AMERICA CORP /DE/TRIM67,24244,967-33.1%$238.8K2025-Q3
BANK OF AMERICA CORP /DE/TRIM93,08767,242-27.8%$230.6K2025-Q2
UBS Group AGADD155,571279,667+79.8%$827.8K2025-Q1
CITADEL ADVISORS LLCNEAR_EXIT180,72532,900-81.8%$97.4K2025-Q1
CAUSEWAY CAPITAL MANAGEMENT LLCNEW14,095$41.7K2025-Q1
CITADEL ADVISORS LLCDOUBLED43,989180,725+310.8%$551.2K2024-Q4
UBS Group AGDOUBLED27,094155,571+474.2%$474.5K2024-Q4
WELLS FARGO & COMPANY/MNADD16,80322,929+36.5%$69.9K2024-Q4
CHARLES SCHWAB INVESTMENT MANAGEMENT INCNEW117,666$300.0K2024-Q3
3 unique insiders with 0 transactions. Net insider value: $0.00 ($0.00 bought, $0.00 sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
Feb 18, 2026AUERBACH ALAN HPresident and CEOA159,778$0.00$0.00
Feb 18, 2026AUERBACH ALAN HPresident and CEOA227,474$0.00$0.00
Feb 18, 2026HUNT DOUGLAS MSee RemarksA49,394$0.00$0.00
Feb 18, 2026HUNT DOUGLAS MSee RemarksA70,321$0.00$0.00
Feb 18, 2026NOUGUES MAXIMO FChief Financial OfficerA46,739$0.00$0.00
Feb 18, 2026NOUGUES MAXIMO FChief Financial OfficerA66,541$0.00$0.00
1 SEC filing reports analyzed. Sentiment: 0 bullish, 0 bearish, 1 mixed, 0 neutral. Avg impact: 6.0/10.

No press releases analyzed yet. Press releases are collected from GlobeNewsWire and analyzed by the LLM pipeline.

Historical analyst distribution (last covering-analyst action Feb 2025): 0% buy across 6 analysts — 0 strong buy, 0 buy, 3 hold, 1 sell, 2 strong sell. No current recommendation available.

Analyst Price Targets

Historical data — last covering-analyst action Feb 2025. No current recommendation available.
$5.00 mean target (Feb 2025)
$5.00 Low $5.00 High
MetricValue
Current Price$7.02
Target Low$5.00
Target Mean$5.00
Target Median$5.00
Target High$5.00
# Analysts1
Recommendation— (no recent coverage)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$0.07 $0.07 $0.07 -53.3% +0.0% $0.1B 1.1% 1
Next Q
2026-09-30
$0.19 $0.19 $0.19 -9.5% -9.5% $0.1B 11.9% 1
Current FY
2026-12-31
$0.45 $0.45 $0.45 -40.0% +12.5% 1↑ 0↓ $0.2B -2.8% 1
Next FY
2027-12-31
$0.35 $0.35 $0.35 -22.2% -46.2% 1↑ 0↓ $0.2B -1.4% 1

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$0.070
7d ago$0.070
30d ago$0.070
60d ago$0.070
90d ago$0.120-0.050
14 analyst firms have rated this stock: 2 upgrades, 7 downgrades, 4 initiations.

Historical Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
Feb 28, 2025 HC Wainwright & Co. REITERATE Buy Buy
Dec 23, 2024 HC Wainwright & Co. REITERATE Buy Buy
Nov 20, 2024 HC Wainwright & Co. REITERATE Buy Buy
Nov 8, 2024 HC Wainwright & Co. REITERATE Buy Buy
Aug 2, 2024 HC Wainwright & Co. REITERATE Buy Buy
Jul 26, 2024 HC Wainwright & Co. REITERATE Buy Buy
Jun 4, 2024 HC Wainwright & Co. REITERATE Buy Buy
Jun 3, 2024 HC Wainwright & Co. REITERATE Buy Buy
May 20, 2024 HC Wainwright & Co. REITERATE Buy Buy
May 3, 2024 HC Wainwright & Co. REITERATE Buy Buy
Mar 1, 2024 HC Wainwright & Co. MAINTAIN Buy Buy
Feb 13, 2024 HC Wainwright & Co. REITERATE Buy Buy
Sep 20, 2023 HC Wainwright & Co. REITERATE Buy Buy
Aug 4, 2023 HC Wainwright & Co. REITERATE Buy Buy
Jun 5, 2023 HC Wainwright & Co. REITERATE Buy Buy
May 5, 2023 HC Wainwright & Co. REITERATE Buy
Mar 6, 2023 HC Wainwright & Co. REITERATE Buy
Aug 5, 2022 HC Wainwright & Co. MAINTAIN Buy
May 6, 2022 HC Wainwright & Co. MAINTAIN Buy
Sep 28, 2021 Citigroup UPGRADE Neutral Buy
Aug 6, 2021 RBC Capital MAINTAIN Sector Perform
Aug 6, 2021 Goldman Sachs MAINTAIN Sell
Aug 10, 2020 Citigroup MAINTAIN Neutral
Aug 7, 2020 SVB Leerink MAINTAIN Market Perform
May 20, 2020 Cantor Fitzgerald MAINTAIN Neutral
Dec 6, 2019 HC Wainwright & Co. INITIATE Buy
Oct 8, 2019 Goldman Sachs DOWNGRADE Neutral Sell
Aug 9, 2019 Barclays MAINTAIN Underweight
May 10, 2019 Citigroup DOWNGRADE Buy Neutral
May 10, 2019 Cantor Fitzgerald DOWNGRADE Overweight Neutral
Mar 1, 2019 Citigroup MAINTAIN Buy Buy
Jan 17, 2019 Leerink Swann INITIATE Market Perform
Jan 3, 2019 Guggenheim DOWNGRADE Buy Neutral
Nov 19, 2018 Goldman Sachs UPGRADE Sell Neutral
Nov 2, 2018 JP Morgan MAINTAIN Underweight Underweight
Nov 2, 2018 Cantor Fitzgerald MAINTAIN Overweight Overweight
Nov 2, 2018 Barclays DOWNGRADE Equal-Weight Underweight
Oct 1, 2018 Cantor Fitzgerald INITIATE Overweight
Sep 18, 2018 Citigroup MAINTAIN Buy Buy
Sep 17, 2018 Goldman Sachs INITIATE Sell
Aug 10, 2018 JP Morgan MAINTAIN Overweight Overweight
Jun 28, 2018 Citigroup MAINTAIN Buy Buy
Apr 12, 2018 Barclays DOWNGRADE Overweight Equal-Weight
Mar 9, 2018 Stifel MAINTAIN Buy Buy
Mar 2, 2018 Barclays MAINTAIN Overweight Overweight
Jan 24, 2018 JP Morgan MAINTAIN Overweight Overweight
Jan 24, 2018 Credit Suisse MAINTAIN Outperform Outperform
Jan 24, 2018 B of A Securities MAINTAIN Buy Buy
Jan 24, 2018 Citigroup MAINTAIN Buy Buy
Jan 24, 2018 Cowen & Co. DOWNGRADE Outperform Market Perform

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 2026003120%
May 1, 2026003120%
Apr 1, 2026003120%
Mar 1, 2026003120%
Feb 1, 2026003120%
Jan 1, 2026003220%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

50°
Neutral
Bearish Neutral Bullish
1 mentions 0 bullish 0 bearish 1 time period

Reddit Sentiment History

DateMentionsSentimentBullishBearishThreads
Feb 25, 2026156° Neutral001
May 7, 2026
earnings_calendar
PBYI Q1 2026 Earnings Scheduled — 2026-05-07
Apr 30, 2026
earnings_calendar
PBYI Q1 2026 Earnings Scheduled — 2026-04-30
Feb 26, 2026
earnings_calendar
PBYI Q4 2025 Earnings After Market Close — 2026-02-26
Feb 24, 2026
Clinical Trial
Neratinib and Paclitaxel With or Without Pertuzumab and Trastuzumab Before Combination Chemotherapy in Treating Patients With Metastatic or Locally Advanced Breast Cancer
Phase Phase 2 — TERMINATED