OMER

OMEROS CORP

Nasdaq · Pharmaceutical Preparations · Inc. WA · CIK 0001285819
$11.60 -3.01% $865.6M
High Impact Filing (9/10)4 Institutional Exits
Vol
Market Cap$865.6M
Cap SizeSmall Cap
Analyst ConsensusStrong Buy (73%)
Inst. Holders7 funds
Inst. Value$99.9M
Inst. Activity1 buys / 4 sells
Reddit Sentiment70° Bullish
SEC Reports2
Exchange Nasdaq·Sector Pharmaceutical Preparations·Inc. WA·CIK 0001285819·Prev Close $11.96

Recent Activity

May 13, 2026 SEC
Omeros reported Q1 2026 results with first-ever YARTEMLEA commercial sales of $9.9M net, GAAP net income of $56.1M (vs a
8-K — Impact 6/10
Apr 21, 2026 SEC
Omeros reported a massive earnings beat for Q4 2025, driven by a $237.6M gain from the zaltenibart sale to Novo Nordisk
8-K — Impact 9/10
Feb 18, 2026 Insider
Demopulos Gregory A MD sold 400,000 shares
Chairman, CEO & President @ $10.27 ($4.1M)
Feb 18, 2026 Insider
Demopulos Gregory A MD sold 357,678 shares
Chairman, CEO & President @ $11.93 ($4.3M)
Feb 18, 2026 Insider
Demopulos Gregory A MD sold 400,000 shares
Chairman, CEO & President @ $0.00 ($0.00)
Inst.
TWO SIGMA INVESTMENTS, LP — TRIM
524,757 shares ($9.0M)
Inst.
MORGAN STANLEY — NEAR_EXIT
386,152 shares ($6.6M)
May 19, 2026 short_volume
Short Volume: OMER — 67.0% short (0.3M / 0.5M)
Short: 343,078 | Exempt: 0 | TRF Vol: 512,032 | Short Ratio: 67.0% | Off-exchange volume (dark pool

Price Targets

$33.50 +188.8% upside Strong Buy
Current $11.60 Low $27.00 Median $33.50 High $40.00 2 analysts
$27.00 $40.00

Analyst Ratings

Buy73% buy · 11 analysts
3Strong Buy
5Buy
3Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
May 14, 2026 HC Wainwright & Co. REITERATE Buy → Buy
Apr 21, 2026 D. Boral Capital MAINTAIN Buy → Buy
Jan 27, 2026 D. Boral Capital MAINTAIN Buy → Buy
Jan 8, 2026 HC Wainwright & Co. MAINTAIN Buy → Buy
Jan 8, 2026 D. Boral Capital MAINTAIN Buy → Buy

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $0.09 ▲ +122.2% $-0.27 — $0.80 116% YoY 3
Next Q $-0.20 ▲ +44.6% $-0.32 — $-0.05 39% YoY 3
Current FY $0.42 ▲ +127.5% $-0.13 — $0.89 -80% YoY 3
Next FY $0.54 ▼ -60.8% $-0.38 — $1.68 28% YoY 3

Top Institutional Holders

FundValueMove
VANGUARD GROUP INC$68.9M
CHARLES SCHWAB INVESTMENT MANAGEMENT$10.2MNEW
TWO SIGMA INVESTMENTS, LP$9.0MTRIM
MORGAN STANLEY$6.6MNEAR_EXIT
WELLS FARGO & COMPANY/MN$2.8MDOUBLED

Recent Insider Trades

DateInsiderTypeValue
Feb 18, 2026Demopulos GregoryM$4.1M
Feb 18, 2026Demopulos GregoryF$4.3M
Feb 18, 2026Demopulos GregoryM$0.00

Reddit Sentiment

70°
Bullish
Bearish Neutral Bullish
6 mentions 4 bullish 0 bearish
7 institutional holders with $99.9M total value (5,815,602 shares) as of 2025-Q4. Top holders: VANGUARD, CHARLES, TWO. Net selling activity: 4 institutions trimmed/exited vs 1 added.

Top Institutional Holders — 2025-Q4

#FundSharesValue% of TrackedLast Move
1VANGUARD GROUP INC4,013,315$68.9M69.0%
2CHARLES SCHWAB INVESTMENT MANAGEMENT INC593,222$10.2M10.2%NEW
3TWO SIGMA INVESTMENTS, LP524,757$9.0M9.0%TRIM -43.8%
4MORGAN STANLEY386,152$6.6M6.6%NEAR_EXIT -80.6%
5WELLS FARGO & COMPANY/MN165,280$2.8M2.8%DOUBLED +164.9%
6BANK OF AMERICA CORP /DE/114,808$2.0M2.0%TRIM -58.3%
7FMR LLC18,068$310.3K0.3%ADD +37.0%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
TWO SIGMA INVESTMENTS, LPTRIM933,314524,757-43.8%$9.0M2025-Q4
MORGAN STANLEYNEAR_EXIT1,989,734386,152-80.6%$6.6M2025-Q4
BANK OF AMERICA CORP /DE/TRIM275,418114,808-58.3%$2.0M2025-Q4
FMR LLCADD13,19018,068+37.0%$310.3K2025-Q4
RENAISSANCE TECHNOLOGIES LLCEXIT344,5000-100.0%$0.002025-Q4
MORGAN STANLEYADD1,355,5591,989,734+46.8%$8.2M2025-Q3
TWO SIGMA INVESTMENTS, LPADD670,219933,314+39.3%$3.8M2025-Q3
MORGAN STANLEYADD760,3601,355,559+78.3%$4.1M2025-Q2
UBS Group AGADD660,657868,500+31.5%$2.6M2025-Q2
TWO SIGMA INVESTMENTS, LPDOUBLED105,639670,219+534.4%$2.0M2025-Q2
RENAISSANCE TECHNOLOGIES LLCNEW382,700$1.1M2025-Q2
BANK OF AMERICA CORP /DE/DOUBLED112,200250,959+123.7%$752.9K2025-Q2
WELLS FARGO & COMPANY/MNDOUBLED46,206122,387+164.9%$367.2K2025-Q2
MORGAN STANLEYDOUBLED333,882760,360+127.7%$6.3M2025-Q1
CITADEL ADVISORS LLCADD330,625415,926+25.8%$3.4M2025-Q1
TWO SIGMA INVESTMENTS, LPTRIM162,991105,639-35.2%$868.4K2025-Q1
WELLS FARGO & COMPANY/MNADD33,14846,206+39.4%$379.8K2025-Q1
FMR LLCTRIM19,36813,340-31.1%$109.7K2025-Q1
UBS Group AGADD450,074849,187+88.7%$8.4M2024-Q4
CITADEL ADVISORS LLCADD214,712330,625+54.0%$3.3M2024-Q4
CHARLES SCHWAB INVESTMENT MANAGEMENT INCNEW485,035$1.9M2024-Q3
MORGAN STANLEYADD197,351297,926+51.0%$1.2M2024-Q3
1 unique insiders with 0 transactions. Net insider value: $0.00 ($0.00 bought, $0.00 sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
Feb 18, 2026Demopulos Gregory A MDChairman, CEO & PresidentM400,000$10.27$4.1M
Feb 18, 2026Demopulos Gregory A MDChairman, CEO & PresidentF357,678$11.93$4.3M
Feb 18, 2026Demopulos Gregory A MDChairman, CEO & PresidentM400,000$0.00$0.00

No press releases analyzed yet. Press releases are collected from GlobeNewsWire and analyzed by the LLM pipeline.

Current analyst consensus: Buy (73% buy). Based on 11 analysts: 3 strong buy, 5 buy, 3 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$33.50 mean target +188.8% upside Strong Buy (2.00)
$27.00 Low $40.00 High
MetricValue
Current Price$11.60
Target Low$27.00
Target Mean$33.50
Target Median$33.50
Target High$40.00
# Analysts2
RecommendationStrong Buy (2.00)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$0.09 $-0.27 $0.80 116.3% +122.2% 1↑ 0↓ $0.0B 0.0% 3
Next Q
2026-09-30
$-0.20 $-0.32 $-0.05 38.5% +44.6% 1↑ 0↓ $0.0B 0.0% 3
Current FY
2026-12-31
$0.42 $-0.13 $0.89 -79.8% +127.5% $0.1B 0.0% 3
Next FY
2027-12-31
$0.54 $-0.38 $1.68 27.6% -60.8% 0↑ 1↓ $0.2B 136.2% 3

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$0.087
7d ago$-0.235+0.322
30d ago$-0.390+0.477
60d ago$-0.610+0.697
90d ago$-0.610+0.697
2 analyst firms have rated this stock: 0 upgrades, 0 downgrades, 0 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
May 14, 2026 HC Wainwright & Co. REITERATE Buy Buy
Apr 21, 2026 D. Boral Capital MAINTAIN Buy Buy
Jan 27, 2026 D. Boral Capital MAINTAIN Buy Buy
Jan 8, 2026 HC Wainwright & Co. MAINTAIN Buy Buy
Jan 8, 2026 D. Boral Capital MAINTAIN Buy Buy
Dec 24, 2025 D. Boral Capital MAINTAIN Buy Buy
Dec 1, 2025 D. Boral Capital MAINTAIN Buy Buy

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
May 1, 20263530073%
Apr 1, 20263530073%
Mar 1, 20263530073%
Feb 1, 20263530073%
Jan 1, 20263530073%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

70°
Bullish
Bearish Neutral Bullish
6 mentions 4 bullish 0 bearish 6 time periods

Reddit Sentiment History

DateMentionsSentimentBullishBearishThreads
May 18, 2026160° Warm101
May 18, 2026160° Warm101
Apr 25, 2026160° Warm101
Apr 25, 2026160° Warm101
Apr 15, 2026150° Neutral001
Apr 15, 2026150° Neutral001

Recent Reddit Threads

r/wallstreetbets Neutral 1mo ago
OMER: A Mid-Size Biotech Company
▲ 1 💬 0 ⚡ 0.5
r/stocks Bullish 26d 23h ago
OMER: A Biotech on the Rise
▲ 1 💬 0 ⚡ 0.5
r/wallstreetbets Bullish 3d 23h ago
OMER: A Biotech on the Rise
▲ 1 💬 1 ⚡ 0.5
May 19, 2026
short_volume
Short Volume: OMER — 67.0% short (0.3M / 0.5M)
Short: 343,078 | Exempt: 0 | TRF Vol: 512,032 | Short Ratio: 67.0% | Off-exchange volume (dark pool + OTC)
May 18, 2026
short_volume
Short Volume: OMER — 81.2% short (0.6M / 0.8M)
Short: 644,909 | Exempt: 42,638 | TRF Vol: 793,757 | Short Ratio: 81.2% | Off-exchange volume (dark pool + OTC)
May 15, 2026
short_volume
Short Volume: OMER — 75.0% short (1.0M / 1.3M)
Short: 984,684 | Exempt: 58,752 | TRF Vol: 1,312,696 | Short Ratio: 75.0% | Off-exchange volume (dark pool + OTC)
May 14, 2026
short_volume
Short Volume: OMER — 77.6% short (1.2M / 1.5M)
Short: 1,176,891 | Exempt: 84,954 | TRF Vol: 1,516,582 | Short Ratio: 77.6% | Off-exchange volume (dark pool + OTC)
May 13, 2026
earnings_calendar
OMER Q1 2026 Earnings Scheduled — 2026-05-13
May 13, 2026
short_volume
Short Volume: OMER — 74.4% short (0.6M / 0.8M)
Short: 600,975 | Exempt: 1,372 | TRF Vol: 807,862 | Short Ratio: 74.4% | Off-exchange volume (dark pool + OTC)
May 12, 2026
earnings_calendar
OMER Q1 2026 Earnings Scheduled — 2026-05-12
Apr 30, 2026
short_interest
FTD: OMER — 81,853 shares ($1.2M) failed to deliver
Settlement: 20260430, Price: $14.56, FTD Value: $1,191,779.68, OMEROS CORPORATION COM STK
Apr 28, 2026
short_volume
Short Volume: OMER — 57.1% short (0.4M / 0.7M)
Short: 411,650 | Exempt: 1,683 | TRF Vol: 721,308 | Short Ratio: 57.1% | Off-exchange volume (dark pool + OTC)
Apr 27, 2026
short_interest
FTD: OMER — 83,249 shares ($1.1M) failed to deliver
Settlement: 20260427, Price: $13.53, FTD Value: $1,126,358.97, OMEROS CORPORATION COM STK
Apr 24, 2026
short_volume
Short Volume: OMER — 69.4% short (0.4M / 0.6M)
Short: 446,536 | Exempt: 3,041 | TRF Vol: 643,713 | Short Ratio: 69.4% | Off-exchange volume (dark pool + OTC)
Apr 1, 2026
Clinical Trial
Safety Study of IgAN, LN, MN, & C3 Glomerulopathy Including Dense Deposit Disease Treated With OMS721
Phase Phase 2 — TERMINATED
Mar 31, 2026
short_interest
FTD: OMER — 140,721 shares ($1.4M) failed to deliver
Settlement: 20260331, Price: $9.81, FTD Value: $1,380,473.01, OMEROS CORPORATION COM STK
Mar 31, 2026
earnings_calendar
OMER Q4 2025 Earnings After Market Close — 2026-03-31
Mar 30, 2026
earnings_calendar
OMER Q4 2025 Earnings After Market Close — 2026-03-30
Mar 18, 2026
short_interest
FTD: OMER — 66,390 shares ($0.7M) failed to deliver
Settlement: 20260318, Price: $11.27, FTD Value: $748,215.3, OMEROS CORPORATION COM STK