LONA

LeonaBio, Inc.

Nasdaq · Biological Products, (No Diagnostic Substances) · CIK 0001620463
$8.35 -1.65% $78.4M
Insider Selling Cluster (4 insiders)
Vol
Market Cap$78.4M
Cap SizeMicro Cap
Analyst ConsensusStrong Buy (89%)
Inst. Holders12 funds
Inst. Value$4.3M
Inst. Activity2 buys / 0 sells
Insider Activity0B / 4S
Insider Net $-$49.1K
SEC Reports4
Press Releases2
Exchange Nasdaq·Sector Biological Products, (No Diagnostic Substances)·CIK 0001620463·Prev Close $8.49

Recent Activity

May 27, 2026 other
LeonaBio to Participate in Upcoming Medical and Industry Meetings in June
<p>BOTHELL, Wash., May 27, 2026 (GLOBE NEWSWIRE) -- <strong>LeonaBio, Inc.</strong> (NASDAQ: LONA)
May 11, 2026 SEC
LeonaBio, Inc. filed a DEFA14A (additional definitive proxy soliciting materials) providing notice of its 2026 Annual Me
DEFA14A — Impact 2/10
May 8, 2026 SEC
Natalie C. Holles filed an initial statement of beneficial ownership (Form 3) with the SEC, indicating her status as an
3 — Impact 2/10
May 5, 2026 Insider
Holles Natalie C. was granted 56,000 shares
Director
May 5, 2026 Insider
Silverman Peter B. was granted 56,000 shares
Director
May 5, 2026 Insider
Callori Fred was granted 56,000 shares
Director
Mar 6, 2026 SEC
LeonaBio's entire C-suite — including the CEO, CFO, CMO, and CSO — sold shares in the open market on March 4, 2026, imme
CLUSTER — Impact 3/10
Inst.
BlackRock, Inc. — ADD
56,051 shares ($576.2K)

Price Targets

$18.00 +115.6% upside Strong Buy
Current $8.35 Low $16.00 Median $18.00 High $20.00 2 analysts
$16.00 $20.00

Analyst Ratings

Strong Buy89% buy · 9 analysts
2Strong Buy
6Buy
1Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
May 27, 2026 Piper Sandler INITIATE Overweight
Feb 19, 2026 Mizuho UPGRADE Neutral → Outperform

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-1.36 ▲ +47.3% $-1.90 — $-0.88 25% YoY 3
Next Q $-0.71 ▲ +70.2% $-0.91 — $-0.57 58% YoY 3
Current FY $-3.12 ▲ +37.8% $-4.35 — $-1.87 87% YoY 3
Next FY $-1.79 ▲ +22.7% $-2.68 — $-1.21 43% YoY 3

Top Institutional Holders

FundValueMove
VANGUARD CAPITAL MANAGEMENT LLC$2.0M
RENAISSANCE TECHNOLOGIES LLC$660.2KADD
BlackRock, Inc.$576.2KADD
VANGUARD FIDUCIARY TRUST CO$411.6K
BANK OF AMERICA CORP$334.8K

Recent Insider Trades

DateInsiderTypeValue
May 5, 2026Holles NatalieA$0.00
May 5, 2026Silverman PeterA$0.00
May 5, 2026Callori FredA$0.00
Apr 9, 2026EDELMAN JOSEPHA$0.00
Apr 9, 2026JOHNSON JAMESA$0.00
12 institutional holders with $4.3M total value (421,306 shares) as of 2026-Q1. Top holders: VANGUARD, RENAISSANCE, BlackRock,. Net buying activity: 2 institutions added/increased vs 0 reduced.

Top Institutional Holders — 2026-Q1

#FundSharesValue% of TrackedLast Move
1VANGUARD CAPITAL MANAGEMENT LLC194,760$2.0M46.2%
2RENAISSANCE TECHNOLOGIES LLC64,222$660.2K15.2%ADD +44.7%
3BlackRock, Inc.56,051$576.2K13.3%ADD +48.9%
4VANGUARD FIDUCIARY TRUST CO40,039$411.6K9.5%
5BANK OF AMERICA CORP /DE/32,566$334.8K7.7%
6STATE STREET CORP16,337$167.9K3.9%ADD +52.2%
7TWO SIGMA INVESTMENTS, LP13,276$136.5K3.2%
8ROYAL BANK OF CANADA2,225$23.0K0.5%
9Vanguard Global Advisers, LLC1,325$13.6K0.3%
10MORGAN STANLEY471$4.8K0.1%
11JONES FINANCIAL COMPANIES LLLP33$296.000.0%
12CITIGROUP INC1$10.000.0%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
BlackRock, Inc.ADD37,64356,051+48.9%$576.2K2026-Q1
STATE STREET CORPADD10,73716,337+52.2%$167.9K2026-Q1
RENAISSANCE TECHNOLOGIES LLCADD51,92475,147+44.7%$568.9K2025-Q4
15 unique insiders with 23 transactions. Net insider value: -$49.1K ($0.00 bought, $49.1K sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
May 5, 2026Holles Natalie C.DirectorAWARD56,000
May 5, 2026Silverman Peter B.DirectorAWARD56,000
May 5, 2026Callori FredDirectorAWARD56,000
Apr 9, 2026EDELMAN JOSEPHDirectorAWARD28,000
Apr 9, 2026JOHNSON JAMES ADirectorAWARD28,000
Apr 9, 2026Romano Kelly ADirectorAWARD28,000
Apr 9, 2026Litton Mark JamesPRESIDENT and CEOAWARD750,000
Apr 9, 2026Worthington MarkGENERAL COUNSEL and CCOAWARD300,000
Apr 9, 2026FLUKE JOHN M JRDirectorAWARD28,000
Apr 9, 2026San Martin JavierCHIEF MEDICAL OFFICERAWARD350,000
Apr 9, 2026Renninger RobertCHIEF FINANCIAL OFFICERAWARD300,000
Apr 9, 2026PICKERING GRANTDirectorAWARD28,000
Apr 9, 2026Kosacz BarbaraDirectorAWARD28,000
Apr 9, 2026CHURCH KEVINCHIEF SCIENTIFIC OFFICERAWARD300,000
Apr 9, 2026Panzara Michael A.DirectorAWARD28,000
Mar 4, 2026Litton Mark JamesPRESIDENT and CEOSELL5,156$5.37$27.7K
Mar 4, 2026Renninger RobertCHIEF FINANCIAL OFFICERSELL906$5.37$4.9K
Mar 4, 2026CHURCH KEVINCHIEF SCIENTIFIC OFFICERSELL1,359$5.37$7.3K
Mar 4, 2026San Martin JavierCHIEF MEDICAL OFFICERSELL1,720$5.37$9.2K
Mar 3, 2026Litton Mark JamesPRESIDENT and CEOEXERCISE22,254
Mar 3, 2026San Martin JavierCHIEF MEDICAL OFFICEREXERCISE7,418
Mar 3, 2026Renninger RobertCHIEF FINANCIAL OFFICEREXERCISE3,900
Mar 3, 2026CHURCH KEVINCHIEF SCIENTIFIC OFFICEREXERCISE5,856
Current analyst consensus: Strong Buy (89% buy). Based on 9 analysts: 2 strong buy, 6 buy, 1 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$18.00 mean target +115.6% upside Strong Buy (1.75)
$16.00 Low $20.00 High
MetricValue
Current Price$8.35
Target Low$16.00
Target Mean$18.00
Target Median$18.00
Target High$20.00
# Analysts2
RecommendationStrong Buy (1.75)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-1.36 $-1.90 $-0.88 24.6% +47.3% $0.0B 0.0% 3
Next Q
2026-09-30
$-0.71 $-0.91 $-0.57 57.7% +70.2% $0.0B 0.0% 3
Current FY
2026-12-31
$-3.12 $-4.35 $-1.87 87.4% +37.8% 1↑ 1↓ $0.0B 0.0% 3
Next FY
2027-12-31
$-1.79 $-2.68 $-1.21 42.6% +22.7% 1↑ 1↓ $0.0B 0.0% 3

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-1.357
7d ago$-1.085-0.272
30d ago$-2.575+1.218
60d ago$-1.955+0.598
90d ago$-2.890+1.533
2 analyst firms have rated this stock: 1 upgrades, 0 downgrades, 1 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
May 27, 2026 Piper Sandler INITIATE Overweight
Feb 19, 2026 Mizuho UPGRADE Neutral Outperform

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 20262610089%
May 1, 20262520078%
Apr 1, 20262520078%
Mar 1, 20262420075%
Feb 1, 2026004120%
Jan 1, 2026004120%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

No Reddit sentiment data available yet. Sentiment is analyzed from Reddit investment communities on a rolling basis.

May 27, 2026
other
LeonaBio to Participate in Upcoming Medical and Industry Meetings in June
<p>BOTHELL, Wash., May 27, 2026 (GLOBE NEWSWIRE) -- <strong>LeonaBio, Inc.</strong> (NASDAQ: LONA), a clinical-stage biopharmaceutical company dedic
May 7, 2026
other
LeonaBio Enhances Board of Directors with Appointments of Fred Callori, J.D., Natalie Holles and Peter B. Silverman, J.D.
LeonaBio, Inc. (NASDAQ: LONA), announced the appointment of Fred Callori, J.D., Natalie Holles, and Peter Silverman, J.D. to its Board of Directors.
May 7, 2026
earnings_calendar
LONA Q1 2026 Earnings Scheduled — 2026-05-07
Apr 23, 2026
fda
LeonaBio to Host Virtual Key Opinion Leader Event Highlighting Potential of Lasofoxifene in Treatment-Resistant ER+/HER2-, ESR1-Mutated Metastatic Breast Cancer
<p align="center"><em>Management to be Joined by Two Clinical Leaders in the Breast Cancer Field </em></p>
Mar 26, 2026
earnings
LeonaBio Reports Full Year 2025 Financial Results and Provides Business Update
<p align="center"><em>Acquired License to Phase 3 Lasofoxifene Development Program of Novel Selective Estrogen Receptor Modulator (SERM), a Potential
Mar 19, 2026
earnings_calendar
LONA Q4 2025 Earnings After Market Close — 2026-03-19
Mar 2, 2026
earnings_calendar
LONA Q4 2025 Earnings After Market Close — 2026-03-02