FULC

Fulcrum Therapeutics, Inc.

Nasdaq · Pharmaceutical Preparations · Inc. DE · CIK 0001680581
$6.47 +1.89% $423.0M
Vol
Market Cap$423.0M
Cap SizeSmall Cap
Inst. Holders7 funds
Inst. Value$51.3M
Inst. Activity2 buys / 2 sells
Insider Activity0B / 2S
Insider Net $-$323.9K
SEC Reports2
Press Releases1
Exchange Nasdaq·Sector Pharmaceutical Preparations·Inc. DE·CIK 0001680581·Prev Close $6.35

Recent Activity

May 8, 2026 other
Fulcrum Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
<p>CAMBRIDGE, Mass., May 08, 2026 (GLOBE NEWSWIRE) -- Fulcrum Therapeutics, Inc.<sup>®</sup> (Nasd
Apr 27, 2026 SEC
Fulcrum Therapeutics terminated a license agreement for its Diamond-Blackfan anemia program, reported Q1 2026 earnings w
8-K — Impact 6/10
Apr 27, 2026 SEC
Fulcrum Therapeutics reported a net loss of $18.9 million for Q1 2026 with EPS of $-0.25, narrowly missing consensus EPS
PRESS-RELEASE — Impact 6/10
Apr 23, 2026 Insider
Lehrer-Graiwer Joshua sold 64,000 shares
Director @ $0.00 ($0.00)
Feb 2, 2026 Insider
Musso Alan A sold 170,000 shares
Chief Financial Officer @ $0.00 ($0.00)
Feb 2, 2026 Insider
Oltmans Curtis Gale sold 170,000 shares
Chief Legal Officer @ $0.00 ($0.00)
Inst.
BANK OF AMERICA CORP — ADD
231,177 shares ($2.6M)
Inst.
WELLS FARGO & COMPANY/MN — DOUBLED
166,395 shares ($1.9M)

Price Targets

Historical data — last covering-analyst action Jan 2026. No current recommendation available.
$18.90 (Jan 2026)
Current $6.47 Low $8.00 Median $20.50 High $25.00 10 analysts
$8.00 $25.00

Analyst Ratings

Historical distribution81% buy · 16 analysts · last covering-analyst action Jan 2026
5Strong Buy
8Buy
2Hold
1Sell
0Strong Sell
Historical Analyst Actions
DateFirmActionRating
Jan 12, 2026 JP Morgan INITIATE Overweight
Dec 11, 2025 Truist Securities MAINTAIN Buy → Buy
Dec 9, 2025 B of A Securities MAINTAIN Underperform → Underperform
Dec 8, 2025 RBC Capital MAINTAIN Sector Perform → Sector Perform
Dec 8, 2025 Cantor Fitzgerald MAINTAIN Overweight → Overweight

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-0.28 ▲ +10.4% $-0.35 — $-0.24 -0% YoY 11
Next Q $-0.31 ▲ +7.2% $-0.46 — $-0.26 -0% YoY 11
Current FY $-1.17 ▲ +10.0% $-1.55 — $-1.03 1% YoY 11
Next FY $-1.33 ▲ +17.2% $-1.91 — $-0.91 -14% YoY 11

Top Institutional Holders

FundValueMove
VANGUARD GROUP INC$40.3M
CHARLES SCHWAB INVESTMENT MANAGEMENT$4.4MTRIM
BANK OF AMERICA CORP$2.6MADD
WELLS FARGO & COMPANY/MN$1.9MDOUBLED
MORGAN STANLEY$1.9MTRIM

Recent Insider Trades

DateInsiderTypeValue
Apr 23, 2026Lehrer-Graiwer JoshuaA$0.00
Feb 2, 2026Musso AlanA$0.00
Feb 2, 2026Oltmans CurtisA$0.00
Feb 2, 2026Tourangeau GregA$0.00
Feb 2, 2026Sapir AlexA$0.00
7 institutional holders with $51.3M total value (4,536,734 shares) as of 2025-Q4. Top holders: VANGUARD, CHARLES, BANK.

Top Institutional Holders — 2025-Q4

#FundSharesValue% of TrackedLast Move
1VANGUARD GROUP INC3,559,552$40.3M78.5%
2CHARLES SCHWAB INVESTMENT MANAGEMENT INC388,896$4.4M8.6%TRIM -27.5%
3BANK OF AMERICA CORP /DE/231,177$2.6M5.1%ADD +57.0%
4WELLS FARGO & COMPANY/MN166,395$1.9M3.7%DOUBLED +411.9%
5MORGAN STANLEY165,623$1.9M3.7%TRIM -32.1%
6RENAISSANCE TECHNOLOGIES LLC17,400$196.8K0.4%NEAR_EXIT -93.0%
7FMR LLC7,691$87.0K0.2%ADD +61.3%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
BANK OF AMERICA CORP /DE/ADD147,211231,177+57.0%$2.6M2025-Q4
WELLS FARGO & COMPANY/MNDOUBLED32,507166,395+411.9%$1.9M2025-Q4
MORGAN STANLEYTRIM243,835165,623-32.1%$1.9M2025-Q4
RENAISSANCE TECHNOLOGIES LLCNEAR_EXIT248,20017,400-93.0%$196.8K2025-Q4
UBS Group AGDOUBLED135,205301,157+122.7%$2.8M2025-Q3
RENAISSANCE TECHNOLOGIES LLCDOUBLED78,500248,200+216.2%$2.3M2025-Q3
BANK OF AMERICA CORP /DE/DOUBLED45,989147,211+220.1%$1.4M2025-Q3
TWO SIGMA INVESTMENTS, LPEXIT58,9650-100.0%$0.002025-Q3
UBS Group AGADD71,920135,205+88.0%$930.2K2025-Q2
RENAISSANCE TECHNOLOGIES LLCNEAR_EXIT401,10078,500-80.4%$540.1K2025-Q2
TWO SIGMA INVESTMENTS, LPTRIM150,27458,965-60.8%$405.7K2025-Q2
FMR LLCADD4,3186,967+61.3%$47.9K2025-Q2
RENAISSANCE TECHNOLOGIES LLCNEW401,100$1.2M2025-Q1
CHARLES SCHWAB INVESTMENT MANAGEMENT INCTRIM526,045381,359-27.5%$1.1M2025-Q1
MORGAN STANLEYNEAR_EXIT1,531,732285,599-81.4%$822.5K2025-Q1
FMR LLCNEAR_EXIT90,4654,318-95.2%$12.4K2025-Q1
MORGAN STANLEYDOUBLED350,6851,531,732+336.8%$7.2M2024-Q4
CITADEL ADVISORS LLCTRIM1,745,993474,723-72.8%$2.2M2024-Q4
WELLS FARGO & COMPANY/MNADD25,50334,264+34.4%$161.0K2024-Q4
CHARLES SCHWAB INVESTMENT MANAGEMENT INCNEW569,185$2.0M2024-Q3
MORGAN STANLEYTRIM1,234,813350,685-71.6%$1.3M2024-Q3
6 unique insiders with 2 transactions. Net insider value: -$323.9K ($0.00 bought, $323.9K sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
Apr 23, 2026Lehrer-Graiwer JoshuaDirectorA64,000$0.00$0.00
Feb 2, 2026Musso Alan AChief Financial OfficerA170,000$0.00$0.00
Feb 2, 2026Oltmans Curtis GaleChief Legal OfficerA170,000$0.00$0.00
Feb 2, 2026Tourangeau GregPrincipal Accounting OfficerA57,000$0.00$0.00
Feb 2, 2026Sapir AlexSee RemarksA650,000$0.00$0.00
Feb 2, 2026Gould Robert JDirectorSELL15,000$10.72$160.9K
Jan 2, 2026Gould Robert JDirectorSELL15,000$10.87$163.1K
Historical analyst distribution (last covering-analyst action Jan 2026): 81% buy across 16 analysts — 5 strong buy, 8 buy, 2 hold, 1 sell, 0 strong sell. No current recommendation available.

Analyst Price Targets

Historical data — last covering-analyst action Jan 2026. No current recommendation available.
$18.90 mean target (Jan 2026)
$8.00 Low $25.00 High
MetricValue
Current Price$6.47
Target Low$8.00
Target Mean$18.90
Target Median$20.50
Target High$25.00
# Analysts10
Recommendation— (no recent coverage)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-0.28 $-0.35 $-0.24 -0.5% +10.4% 8↑ 2↓ $0.0B 0.0% 11
Next Q
2026-09-30
$-0.31 $-0.46 $-0.26 -0.4% +7.2% 7↑ 3↓ $0.0B 0.0% 11
Current FY
2026-12-31
$-1.17 $-1.55 $-1.03 0.8% +10.0% 8↑ 2↓ $0.0B 0.0% 11
Next FY
2027-12-31
$-1.33 $-1.91 $-0.91 -13.5% +17.2% 8↑ 1↓ $0.0B 0.0% 11

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-0.281
7d ago$-0.286+0.005
30d ago$-0.314+0.033
60d ago$-0.314+0.033
90d ago$-0.296+0.015
7 analyst firms have rated this stock: 0 upgrades, 0 downgrades, 2 initiations.

Historical Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
Jan 12, 2026 JP Morgan INITIATE Overweight
Dec 11, 2025 Truist Securities MAINTAIN Buy Buy
Dec 9, 2025 B of A Securities MAINTAIN Underperform Underperform
Dec 8, 2025 RBC Capital MAINTAIN Sector Perform Sector Perform
Dec 8, 2025 Cantor Fitzgerald MAINTAIN Overweight Overweight
Dec 8, 2025 Piper Sandler REITERATE Overweight Overweight
Dec 8, 2025 HC Wainwright & Co. MAINTAIN Buy Buy
Nov 24, 2025 Truist Securities INITIATE Buy
Nov 24, 2025 HC Wainwright & Co. MAINTAIN Buy Buy

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
May 1, 20265821081%
Apr 1, 20265821081%
Mar 1, 20265821081%
Feb 1, 20265821081%
Jan 1, 20265721080%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

No Reddit sentiment data available yet. Sentiment is analyzed from Reddit investment communities on a rolling basis.

May 8, 2026
other
Fulcrum Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
<p>CAMBRIDGE, Mass., May 08, 2026 (GLOBE NEWSWIRE) -- Fulcrum Therapeutics, Inc.<sup>®</sup> (Nasdaq: FULC), a clinical-stage biopharmaceutical comp
Apr 27, 2026
earnings
Fulcrum Therapeutics Announces Recent Business Highlights and Financial Results for First Quarter 2026
<p align="center"><em>― Presented positive clinical data for pociredir, demonstrating robust and rapid fetal hemoglobin (HbF) induction, improvements
Apr 27, 2026
other
Fulcrum Therapeutics Appoints Josh Lehrer to its Board of Directors
<p>CAMBRIDGE, Mass., April 27, 2026 (GLOBE NEWSWIRE) -- Fulcrum Therapeutics, Inc.<sup>® </sup>(Fulcrum) (NASDAQ: FULC), a clinical-stage biopharmac
Apr 27, 2026
earnings_calendar
FULC Q1 2026 Earnings Scheduled — 2026-04-27
Mar 19, 2026
contract
MedicAlert Foundation, Sickle Cell Disease Association of America, Inc. (SCDAA), and Fulcrum Therapeutics Partner to Accelerate Emergency Department Access to Critical Care Information for People Living with Sickle Cell Disease
Three-year collaboration is aimed at enhancing a key aspect of sickle cell management: expediting care during a pain crisis <pre>Three-year collaborat
Mar 6, 2026
other
Fulcrum Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
<p>CAMBRIDGE, Mass., March 06, 2026 (GLOBE NEWSWIRE) -- Fulcrum Therapeutics, Inc.® (Nasdaq: FULC), a clinical-stage biopharmaceutical company focus
Mar 3, 2026
other
Fulcrum Therapeutics to Participate in the Leerink Partners Global Healthcare Conference
<p>CAMBRIDGE, Mass., March 03, 2026 (GLOBE NEWSWIRE) -- Fulcrum Therapeutics, Inc.<sup>®</sup> (the “Company”) (Nasdaq: FULC), a clinical-stage biop
Feb 24, 2026
earnings_calendar
FULC Q4 2025 Earnings After Market Close — 2026-02-24