DYN

Dyne Therapeutics, Inc.

Nasdaq · Pharmaceutical Preparations · Inc. DE · CIK 0001818794
$16.81 -1.35% $2.8B
Insider Selling Cluster (6 insiders)3 New Institutional Positions
Vol
Market Cap$2.8B
Cap SizeMid Cap
Analyst ConsensusStrong Buy (85%)
Inst. Holders8 funds
Inst. Value$424.5M
Inst. Activity3 buys / 0 sells
Insider Activity7B / 27S
Insider Net $-$22.6M
SEC Reports20
Press Releases5
Exchange Nasdaq·Sector Pharmaceutical Preparations·Inc. DE·CIK 0001818794·Prev Close $17.04

Recent Activity

Jun 8, 2026 Insider
Posner Brian S bought 2,000 shares
Director @ $16.94 ($33.9K)
Jun 8, 2026 short_volume
Short Volume: DYN — 64.0% short (0.4M / 0.6M)
Short: 395,717 | Exempt: 0 | TRF Vol: 618,335 | Short Ratio: 64.0% | Off-exchange volume (dark pool
Jun 5, 2026 Insider
Posner Brian S sold 35,152 shares
Director @ $0.00 ($0.00)
Jun 5, 2026 Insider
Stehman-Breen Catherine sold 35,152 shares
Director @ $0.00 ($0.00)
Jun 3, 2026 SEC
Dyne Therapeutics announced full enrollment (71 participants) of the registrational expansion cohort in its Phase 1/2 AC
8-K — Impact 6/10
Jun 3, 2026 Press
Dyne Therapeutics announced completion of enrollment in the registrational expansion cohort of the Phase 1/2 ACHIEVE tri
Impact 5/10
May 13, 2026 SEC
Director John Cox filed a Form 144 notice of intent to sell 3,311 shares of Dyne Therapeutics common stock, valued at ap
144 — Impact 2/10
May 13, 2026 SEC
Erick Lucera, an officer of Dyne Therapeutics, filed a Form 144 notice of intent to sell 1,448 shares of common stock, w
144 — Impact 2/10

Price Targets

$38.25 +113.4% upside Strong Buy
Current $17.92 Low $17.00 Median $39.50 High $50.00 16 analysts
$17.00 $50.00

Analyst Ratings

Strong Buy85% buy · 20 analysts
7Strong Buy
10Buy
3Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
May 15, 2026 Evercore ISI Group MAINTAIN Outperform → Outperform
May 13, 2026 Bernstein MAINTAIN Market Perform → Market Perform
Mar 9, 2026 Chardan Capital MAINTAIN Buy → Buy
Mar 3, 2026 Morgan Stanley MAINTAIN Overweight → Overweight
Mar 3, 2026 Chardan Capital MAINTAIN Buy → Buy

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-0.75 ▲ +6.0% $-0.84 — $-0.62 23% YoY 11
Next Q $-0.76 ▲ +4.4% $-0.90 — $-0.60 0% YoY 11
Current FY $-3.08 ▲ +3.4% $-3.46 — $-2.78 11% YoY 13
Next FY $-2.98 ▲ +1.8% $-3.89 — $-2.27 3% YoY 12

Top Institutional Holders

FundValueMove
VANGUARD GROUP INC$219.4MADD
FMR LLC$128.5MTRIM
MORGAN STANLEY$23.7MADD
CHARLES SCHWAB INVESTMENT MANAGEMENT$22.5MADD
BANK OF AMERICA CORP$17.3MADD

Recent Insider Trades

DateInsiderTypeValue
Jun 8, 2026Posner BrianBUY$33.9K
Jun 5, 2026Posner BrianA$0.00
Jun 5, 2026Stehman-Breen CatherineA$0.00
Jun 5, 2026Incerti CarloA$0.00
Jun 5, 2026Kersten DirkA$0.00
8 institutional holders with $424.5M total value (21,701,087 shares) as of 2025-Q4. Top holders: VANGUARD, FMR, MORGAN. Net buying activity: 3 institutions added/increased vs 0 reduced.

Top Institutional Holders — 2025-Q4

#FundSharesValue% of TrackedLast Move
1VANGUARD GROUP INC11,215,565$219.4M51.7%ADD +27.6%
2FMR LLC6,569,921$128.5M30.3%TRIM -35.0%
3MORGAN STANLEY1,213,559$23.7M5.6%ADD +84.7%
4CHARLES SCHWAB INVESTMENT MANAGEMENT INC1,151,325$22.5M5.3%ADD +35.2%
5BANK OF AMERICA CORP /DE/882,922$17.3M4.1%ADD +48.1%
6RENAISSANCE TECHNOLOGIES LLC470,645$9.2M2.2%ADD +36.2%
7WELLS FARGO & COMPANY/MN147,831$2.9M0.7%ADD +69.7%
8NORGES BANK49,319$964.7K0.2%NEW

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
RENAISSANCE TECHNOLOGIES LLCADD345,500470,645+36.2%$9.2M2025-Q4
WELLS FARGO & COMPANY/MNADD87,121147,831+69.7%$2.9M2025-Q4
NORGES BANKNEW49,319$964.7K2025-Q4
VANGUARD GROUP INCADD7,651,1579,760,414+27.6%$123.5M2025-Q3
CHARLES SCHWAB INVESTMENT MANAGEMENT INCADD745,0711,007,194+35.2%$12.7M2025-Q3
BANK OF AMERICA CORP /DE/ADD513,801761,112+48.1%$9.6M2025-Q3
UBS Group AGDOUBLED121,792349,388+186.9%$4.4M2025-Q3
RENAISSANCE TECHNOLOGIES LLCNEW345,500$4.4M2025-Q3
WELLS FARGO & COMPANY/MNADD56,70587,121+53.6%$1.1M2025-Q3
NORGES BANKEXIT49,3190-100.0%$0.002025-Q3
BANK OF AMERICA CORP /DE/ADD269,976513,801+90.3%$4.9M2025-Q2
UBS Group AGTRIM357,754121,792-66.0%$1.2M2025-Q2
WELLS FARGO & COMPANY/MNADD40,15856,705+41.2%$539.8K2025-Q2
NORGES BANKNEW49,319$469.5K2025-Q2
FMR LLCTRIM7,996,9315,195,294-35.0%$54.3M2025-Q1
MORGAN STANLEYADD753,5931,391,587+84.7%$14.6M2025-Q1
UBS Group AGTRIM540,112357,754-33.8%$3.7M2025-Q1
NORGES BANKEXIT950,1040-100.0%$0.002025-Q1
NORGES BANKDOUBLED432,327950,104+119.8%$22.4M2024-Q4
MORGAN STANLEYTRIM1,053,262753,593-28.5%$17.8M2024-Q4
WELLS FARGO & COMPANY/MNADD25,07738,754+54.5%$913.0K2024-Q4
MORGAN STANLEYADD559,0521,053,262+88.4%$37.8M2024-Q3
CHARLES SCHWAB INVESTMENT MANAGEMENT INCNEW648,652$23.3M2024-Q3
11 unique insiders with 34 transactions. Net insider value: -$22.6M ($274.8K bought, $22.9M sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
Jun 8, 2026Posner Brian SDirectorBUY2,000$16.94$33.9K
Jun 5, 2026Posner Brian SDirectorA35,152$0.00$0.00
Jun 5, 2026Stehman-Breen CatherineDirectorA35,152$0.00$0.00
Jun 5, 2026Incerti CarloDirectorA35,152$0.00$0.00
Jun 5, 2026Kersten DirkDirectorA35,152$0.00$0.00
Jun 5, 2026Rhodes Jason PDirectorA35,152$0.00$0.00
Jun 5, 2026HURWITZ EDWARDDirectorA35,152$0.00$0.00
Jun 3, 2026Posner Brian SDirectorBUY2,500$17.48$43.7K
May 26, 2026Posner Brian SDirectorBUY2,000$18.21$36.4K
May 20, 2026Posner Brian SDirectorBUY2,500$17.12$42.8K
May 13, 2026Lucera ErickChief Financial OfficerSELL1,448$18.36$26.6K
May 13, 2026Cox JohnCEO & PresidentSELL3,311$18.36$60.8K
May 13, 2026Kerr DouglasChief Medical OfficerSELL1,564$18.36$28.7K
May 13, 2026Friedl-Naderer JohannaChief Commercial OfficerSELL228$18.36$4.2K
May 6, 2026Rhodes Jason PDirectorSELL21,926$18.18$398.6K
May 5, 2026Rhodes Jason PDirectorSELL3,056$18.03$55.1K
May 4, 2026Rhodes Jason PDirectorSELL3,136$18.00$56.4K
Apr 28, 2026Rhodes Jason PDirectorSELL59,870$18.38$1.1M
Apr 27, 2026Rhodes Jason PDirectorSELL45,709$18.15$829.6K
Apr 24, 2026Rhodes Jason PDirectorSELL36,345$18.48$671.7K
Apr 24, 2026Lubner David CharlesDirectorG53,625$0.00$0.00
Apr 23, 2026Rhodes Jason PDirectorSELL19,261$19.19$369.6K
Apr 22, 2026Kersten DirkDirectorSELL2,652$20.00$53.0K
Apr 22, 2026Rhodes Jason PDirectorSELL75,866$19.68$1.5M
Apr 21, 2026Kersten DirkDirectorSELL8,300$20.01$166.1K
Apr 21, 2026Rhodes Jason PDirectorSELL71,499$19.51$1.4M
Apr 20, 2026Kersten DirkDirectorSELL125,274$20.07$2.5M
Apr 20, 2026Rhodes Jason PDirectorSELL71,676$20.06$1.4M
Apr 17, 2026Kersten DirkDirectorSELL211,974$20.29$4.3M
Apr 16, 2026Kersten DirkDirectorSELL11,116$21.10$234.6K
Apr 15, 2026Kersten DirkDirectorSELL81,840$20.27$1.7M
Apr 1, 2026Lucera ErickChief Financial OfficerSELL5,727$18.64$106.8K
Mar 30, 2026Posner Brian SDirectorBUY2,000$17.08$34.2K
Mar 11, 2026Posner Brian SDirectorBUY2,000$19.35$38.7K
Mar 11, 2026Kersten DirkDirectorSELL129,672$19.52$2.5M
Mar 10, 2026Kersten DirkDirectorSELL9,482$18.21$172.7K
Mar 9, 2026Kersten DirkDirectorSELL177,690$17.72$3.1M
Mar 6, 2026Posner Brian SDirectorBUY3,000$15.06$45.2K
Mar 5, 2026Cox JohnCEO & PresidentSELL2,732$14.90$40.7K
Mar 5, 2026Friedl-Naderer JohannaChief Commercial OfficerSELL148$14.90$2.2K
Mar 5, 2026Kerr DouglasChief Medical OfficerSELL904$14.90$13.5K
Feb 12, 2026Kerr DouglasChief Medical OfficerA85,000$0.00$0.00
Feb 12, 2026Kerr DouglasChief Medical OfficerA130,000$0.00$0.00
Feb 12, 2026Cox JohnCEO & PresidentA180,000$0.00$0.00
Feb 12, 2026Cox JohnCEO & PresidentA285,000$0.00$0.00
Feb 12, 2026Friedl-Naderer JohannaChief Commercial OfficerA60,000$0.00$0.00
Feb 12, 2026Friedl-Naderer JohannaChief Commercial OfficerA90,000$0.00$0.00
Feb 12, 2026Lucera ErickChief Financial OfficerA65,000$0.00$0.00
Feb 12, 2026Lucera ErickChief Financial OfficerA105,000$0.00$0.00
20 SEC filing reports analyzed. Sentiment: 1 bullish, 5 bearish, 0 mixed, 14 neutral. Avg impact: 3.5/10.
BULLISH 8-K 6/10
Dyne Therapeutics announced full enrollment (71 participants) of the registrational expansion cohort
Jun 3, 2026
NEUTRAL 144 2/10
Director John Cox filed a Form 144 notice of intent to sell 3,311 shares of Dyne Therapeutics common
May 13, 2026
NEUTRAL 144 2/10
Erick Lucera, an officer of Dyne Therapeutics, filed a Form 144 notice of intent to sell 1,448 share
May 13, 2026
NEUTRAL 8-K 5/10
Dyne Therapeutics reported Q1 2026 net loss of $120.9M ($0.73/share), wider than the $115.4M loss in
May 11, 2026
NEUTRAL 144 2/10
Atlas Venture Fund XI, L.P. filed a Form 144 indicating intent to sell 43,621 shares of Dyne Therape
May 6, 2026
NEUTRAL 144 2/10
Atlas Venture Associates XI, L.P., a major venture capital shareholder, filed a Form 144 indicating
May 6, 2026
NEUTRAL 144 2/10
Atlas Venture Opportunity Fund I, L.P., a major venture investor, filed a Form 144 indicating intent
May 4, 2026
NEUTRAL 144 2/10
Atlas Venture Fund XI, L.P., a major shareholder, filed a Form 144 to sell 6,241 shares of Dyne Ther
May 4, 2026
NEUTRAL 144 2/10
Atlas Venture Associates XI, L.P. filed a Form 144 to sell 61 shares of Dyne Therapeutics, with an e
May 4, 2026
NEUTRAL CLUSTER 3/10
Two Dyne Therapeutics directors sold a total of ~$1.15M in stock over a 7-day window, with Director
Apr 30, 2026
NEUTRAL CLUSTER 4/10
Director Jason P. Rhodes sold $3.4M worth of DYN shares over a five-day window, with total insider s
Apr 28, 2026
BEARISH 144 5/10
Atlas Venture Opportunity Fund I, L.P., a major venture capital backer of Dyne Therapeutics, filed a
Apr 28, 2026
NEUTRAL CLUSTER 2/10
Two Dyne Therapeutics directors, Jason Rhodes and Dirk Kersten, sold a combined $423K in open-market
Apr 27, 2026
BEARISH 144 6/10
Three institutional investors affiliated with Atlas Venture—Atlas Venture Associates XI, L.P., Atlas
Apr 24, 2026
NEUTRAL DEFA14A 3/10
Dyne Therapeutics has filed its definitive proxy statement for the upcoming annual shareholder meeti
Apr 23, 2026
BEARISH CLUSTER 6/10
Two directors at Dyne Therapeutics (DYN) sold over $11.4 million in shares over the past 7 days, inc
Apr 23, 2026
NEUTRAL 144 2/10
Atlas Venture Associates XI, L.P., a shareholder of Dyne Therapeutics, filed a Form 144 notifying in
Apr 20, 2026
BEARISH 144 6/10
Two affiliated venture funds, Atlas Venture Fund XI and Atlas Venture Opportunity Fund I, filed Form
Apr 20, 2026
NEUTRAL CLUSTER 3/10
A mixed insider trading cluster at Dyne Therapeutics shows CFO Erick Lucera selling $107K in shares
Apr 3, 2026
BEARISH 144 5/10
Lucera Erick, an officer of Dyne Therapeutics, filed a Form 144 to notify intent to sell up to 57,27
Apr 1, 2026
Current analyst consensus: Strong Buy (85% buy). Based on 20 analysts: 7 strong buy, 10 buy, 3 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$38.25 mean target +113.4% upside Strong Buy (1.44)
$17.00 Low $50.00 High
MetricValue
Current Price$17.92
Target Low$17.00
Target Mean$38.25
Target Median$39.50
Target High$50.00
# Analysts16
RecommendationStrong Buy (1.44)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-0.75 $-0.84 $-0.62 22.8% +6.0% 5↑ 5↓ $0.0B 0.0% 11
Next Q
2026-09-30
$-0.76 $-0.90 $-0.60 0.0% +4.4% 5↑ 5↓ $0.0B 0.0% 11
Current FY
2026-12-31
$-3.08 $-3.46 $-2.78 11.1% +3.4% 7↑ 6↓ $0.0B 0.0% 13
Next FY
2027-12-31
$-2.98 $-3.89 $-2.27 3.3% +1.8% 4↑ 7↓ $0.1B 0.0% 12

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-0.749
7d ago$-0.749
30d ago$-0.797+0.048
60d ago$-0.797+0.048
90d ago$-0.794+0.045
6 analyst firms have rated this stock: 0 upgrades, 0 downgrades, 0 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
May 15, 2026 Evercore ISI Group MAINTAIN Outperform Outperform
May 13, 2026 Bernstein MAINTAIN Market Perform Market Perform
Mar 9, 2026 Chardan Capital MAINTAIN Buy Buy
Mar 3, 2026 Morgan Stanley MAINTAIN Overweight Overweight
Mar 3, 2026 Chardan Capital MAINTAIN Buy Buy
Mar 3, 2026 HC Wainwright & Co. MAINTAIN Buy Buy
Jan 20, 2026 JP Morgan MAINTAIN Neutral Neutral
Dec 15, 2025 Evercore ISI Group MAINTAIN Outperform Outperform

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 202671030085%
May 1, 202671030085%
Apr 1, 202671030085%
Mar 1, 202671030085%
Feb 1, 202671030085%
Jan 1, 202671030085%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

No Reddit sentiment data available yet. Sentiment is analyzed from Reddit investment communities on a rolling basis.

Jun 8, 2026
short_volume
Short Volume: DYN — 64.0% short (0.4M / 0.6M)
Short: 395,717 | Exempt: 0 | TRF Vol: 618,335 | Short Ratio: 64.0% | Off-exchange volume (dark pool + OTC)
Jun 5, 2026
short_volume
Short Volume: DYN — 56.2% short (0.4M / 0.7M)
Short: 371,592 | Exempt: 986 | TRF Vol: 661,139 | Short Ratio: 56.2% | Off-exchange volume (dark pool + OTC)
Jun 3, 2026
fda
Dyne Therapeutics Announces Completion of Enrollment in Registrational Expansion Cohort of ACHIEVE Trial of Z-Basivarsen for Myotonic Dystrophy Type 1 (DM1)
<p align="center"><em>- Registrational expansion cohort enrolled 71 participants; topline data planned for Q1 2027 - </em></p>
Jun 2, 2026
short_volume
Short Volume: DYN — 69.1% short (0.4M / 0.6M)
Short: 446,219 | Exempt: 0 | TRF Vol: 645,445 | Short Ratio: 69.1% | Off-exchange volume (dark pool + OTC)
Jun 1, 2026
short_volume
Short Volume: DYN — 76.4% short (0.4M / 0.6M)
Short: 434,685 | Exempt: 0 | TRF Vol: 569,161 | Short Ratio: 76.4% | Off-exchange volume (dark pool + OTC)
May 26, 2026
other
Dyne Therapeutics Announces Submission of Biologics License Application (BLA) to U.S. FDA for Z-Rostudirsen in Exon 51 Duchenne Muscular Dystrophy (DMD)
<p align="center"><em>- Submission for Accelerated Approval based on dystrophin as a surrogate endpoint -</em></p>
May 26, 2026
short_volume
Short Volume: DYN — 84.5% short (0.5M / 0.6M)
Short: 546,682 | Exempt: 0 | TRF Vol: 647,191 | Short Ratio: 84.5% | Off-exchange volume (dark pool + OTC)
May 22, 2026
short_volume
Short Volume: DYN — 87.3% short (0.5M / 0.6M)
Short: 490,888 | Exempt: 74 | TRF Vol: 562,518 | Short Ratio: 87.3% | Off-exchange volume (dark pool + OTC)
May 21, 2026
short_volume
Short Volume: DYN — 82.0% short (0.5M / 0.6M)
Short: 452,861 | Exempt: 7,867 | TRF Vol: 551,987 | Short Ratio: 82.0% | Off-exchange volume (dark pool + OTC)
May 20, 2026
activist
Dyne Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
<p>WALTHAM, Mass., May 20, 2026 (GLOBE NEWSWIRE) -- <a href="https://www.globenewswire.com/Tracker?data=yvxOg06WRLoiHP67ePX0j327M-HARlS_VL1qtfxsoAH-
May 20, 2026
fda
Dyne Therapeutics Announces Initiation of Phase 3 FORZETTO Trial of Z-Rostudirsen in Duchenne Muscular Dystrophy (DMD) Ahead of Planned BLA Submission for U.S. Accelerated Approval
<p align="center"><em>- 72-week trial will enroll approximately 90 participants; first site now open for enrollment -</em></p>
May 20, 2026
short_volume
Short Volume: DYN — 83.5% short (0.5M / 0.6M)
Short: 474,982 | Exempt: 7,053 | TRF Vol: 568,856 | Short Ratio: 83.5% | Off-exchange volume (dark pool + OTC)
May 19, 2026
short_volume
Short Volume: DYN — 64.8% short (0.3M / 0.5M)
Short: 326,011 | Exempt: 8,303 | TRF Vol: 502,950 | Short Ratio: 64.8% | Off-exchange volume (dark pool + OTC)
May 13, 2026
other
Dyne Therapeutics to Participate in Upcoming Investor Conferences
<p align="left">WALTHAM, Mass., May 13, 2026 (GLOBE NEWSWIRE) -- <a href="https://www.globenewswire.com/Tracker?data=C-5t0aGnjkHMrOVYKUMNDCAssDb9bzr
May 11, 2026
earnings
Dyne Therapeutics Reports First Quarter 2026 Financial Results and Recent Business Highlights
<p align="center"><em>- Positive pre-BLA meeting completed with FDA for z-rostudirsen in exon 51 DMD; on track for BLA submission in Q2 2026 and poten