DFTX

Definium Therapeutics, Inc.

Nasdaq · Medicinal Chemicals & Botanical Products · Inc. A1 · CIK 0001813814
$20.87 +4.25% $2.2B
Insider Selling Cluster (3 insiders)
Vol
Market Cap$2.2B
Cap SizeMid Cap
Analyst ConsensusStrong Buy (95%)
Insider Activity0B / 3S
Insider Net $-$797.0K
Reddit Sentiment50° Neutral
SEC Reports1
Exchange Nasdaq·Sector Medicinal Chemicals & Botanical Products·Inc. A1·CIK 0001813814·Prev Close $20.02

Recent Activity

May 13, 2026 short_volume
Short Volume: DFTX — 56.5% short (0.3M / 0.5M)
Short: 294,561 | Exempt: 899 | TRF Vol: 521,136 | Short Ratio: 56.5% | Off-exchange volume (dark poo
Apr 27, 2026 SEC
Definium Therapeutics filed definitive additional proxy materials for its 2026 Annual General and Special Meeting to be
DEFA14A — Impact 2/10
Mar 25, 2026 Insider
Barrow Robert sold 24,431 shares
Chief Executive Officer @ $18.47 ($451.2K)
Mar 25, 2026 Insider
Karlin Daniel sold 8,018 shares
Chief Medical Officer @ $18.47 ($148.1K)
Mar 25, 2026 Insider
Sullivan Mark sold 10,702 shares
Chief Legal Officer @ $18.47 ($197.7K)

Price Targets

$39.47 +89.1% upside Strong Buy
Current $20.87 Low $25.00 Median $38.00 High $70.00 15 analysts
$25.00 $70.00

Analyst Ratings

Strong Buy95% buy · 22 analysts
8Strong Buy
13Buy
1Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
May 8, 2026 Piper Sandler MAINTAIN Overweight → Overweight
Apr 22, 2026 Leerink Partners MAINTAIN Outperform → Outperform
Apr 17, 2026 Stifel INITIATE Buy
Apr 16, 2026 Canaccord Genuity MAINTAIN Buy → Buy
Apr 10, 2026 Piper Sandler INITIATE Overweight

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-0.57 ▼ -15.4% $-0.72 — $-0.44 -13% YoY 11
Next Q $-0.56 ▼ -12.9% $-0.66 — $-0.43 28% YoY 11
Current FY $-2.27 ▼ -17.5% $-2.66 — $-1.85 -10% YoY 12
Next FY $-1.58 ▲ +7.5% $-2.62 — $0.30 30% YoY 11

Recent Insider Trades

DateInsiderTypeValue
Mar 25, 2026Barrow RobertSELL$451.2K
Mar 25, 2026Karlin DanielSELL$148.1K
Mar 25, 2026Sullivan MarkSELL$197.7K
Feb 3, 2026Wiley MatthewA$0.00
Feb 3, 2026Roberts BrandiA$0.00

Reddit Sentiment

50°
Neutral
Bearish Neutral Bullish
6 mentions 2 bullish 2 bearish

No institutional holding data available yet. Data is sourced from 13F filings which are filed quarterly.

5 unique insiders with 3 transactions. Net insider value: -$797.0K ($0.00 bought, $797.0K sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
Mar 25, 2026Barrow RobertChief Executive OfficerSELL24,431$18.47$451.2K
Mar 25, 2026Karlin DanielChief Medical OfficerSELL8,018$18.47$148.1K
Mar 25, 2026Sullivan MarkChief Legal OfficerSELL10,702$18.47$197.7K
Feb 3, 2026Wiley Matthew T.Chief Commercial OfficerA115,000$0.00$0.00
Feb 3, 2026Roberts BrandiChief Financial OfficerA150,000$0.00$0.00
Feb 3, 2026Sullivan MarkChief Legal OfficerA125,000$0.00$0.00
Feb 3, 2026Karlin DanielChief Medical OfficerA150,000$0.00$0.00
Feb 3, 2026Barrow RobertChief Executive OfficerA320,000$0.00$0.00
1 SEC filing reports analyzed. Sentiment: 0 bullish, 0 bearish, 0 mixed, 1 neutral. Avg impact: 2.0/10.

No press releases analyzed yet. Press releases are collected from GlobeNewsWire and analyzed by the LLM pipeline.

Current analyst consensus: Strong Buy (95% buy). Based on 22 analysts: 8 strong buy, 13 buy, 1 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$39.47 mean target +89.1% upside Strong Buy (1.25)
$25.00 Low $70.00 High
MetricValue
Current Price$20.87
Target Low$25.00
Target Mean$39.47
Target Median$38.00
Target High$70.00
# Analysts15
RecommendationStrong Buy (1.25)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-0.57 $-0.72 $-0.44 -13.1% -15.4% 0↑ 1↓ $0.0B 0.0% 11
Next Q
2026-09-30
$-0.56 $-0.66 $-0.43 28.4% -12.9% 0↑ 1↓ $0.0B 0.0% 11
Current FY
2026-12-31
$-2.27 $-2.66 $-1.85 -10.4% -17.5% 1↑ 10↓ $0.0B 0.0% 12
Next FY
2027-12-31
$-1.58 $-2.62 $0.30 30.5% +7.5% 5↑ 5↓ $0.0B 0.0% 11

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-0.565
7d ago$-0.525-0.040
30d ago$-0.490-0.075
60d ago$-0.490-0.075
90d ago$-0.453-0.113
8 analyst firms have rated this stock: 0 upgrades, 0 downgrades, 4 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
May 8, 2026 Piper Sandler MAINTAIN Overweight Overweight
Apr 22, 2026 Leerink Partners MAINTAIN Outperform Outperform
Apr 17, 2026 Stifel INITIATE Buy
Apr 16, 2026 Canaccord Genuity MAINTAIN Buy Buy
Apr 10, 2026 Piper Sandler INITIATE Overweight
Mar 2, 2026 HC Wainwright & Co. MAINTAIN Buy Buy
Feb 24, 2026 Wolfe Research INITIATE Outperform
Jan 30, 2026 Jefferies INITIATE Buy
Jan 23, 2026 RBC Capital MAINTAIN Outperform Outperform

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
May 1, 202681310095%
Apr 1, 202671210095%
Mar 1, 202671310095%
Feb 1, 202661310095%
Jan 1, 202651310095%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

50°
Neutral
Bearish Neutral Bullish
6 mentions 2 bullish 2 bearish 6 time periods

Reddit Sentiment History

DateMentionsSentimentBullishBearishThreads
May 20, 2026156° Neutral001
May 20, 2026156° Neutral001
Apr 20, 2026160° Warm101
Apr 20, 2026160° Warm101
Apr 8, 2026140° Cool011
Apr 8, 2026140° Cool011

Recent Reddit Threads

r/wallstreetbets Bearish 1mo ago
Profitable after almost 6 years. -56k comeback.
▲ 1 💬 1 ⚡ 0.5
r/wallstreetbets Neutral 3h 19m ago
Today was a good day
▲ 1 💬 1 ⚡ 0.5
May 13, 2026
short_volume
Short Volume: DFTX — 56.5% short (0.3M / 0.5M)
Short: 294,561 | Exempt: 899 | TRF Vol: 521,136 | Short Ratio: 56.5% | Off-exchange volume (dark pool + OTC)
May 7, 2026
earnings_calendar
DFTX Q1 2026 Earnings Scheduled — 2026-05-07
Apr 30, 2026
short_volume
Short Volume: DFTX — 56.2% short (0.4M / 0.7M)
Short: 412,127 | Exempt: 0 | TRF Vol: 733,328 | Short Ratio: 56.2% | Off-exchange volume (dark pool + OTC)
Apr 22, 2026
short_volume
Short Volume: DFTX — 59.0% short (0.5M / 0.8M)
Short: 454,032 | Exempt: 0 | TRF Vol: 769,862 | Short Ratio: 59.0% | Off-exchange volume (dark pool + OTC)
Apr 21, 2026
short_volume
Short Volume: DFTX — 58.2% short (0.7M / 1.1M)
Short: 657,367 | Exempt: 60 | TRF Vol: 1,130,438 | Short Ratio: 58.2% | Off-exchange volume (dark pool + OTC)
Apr 6, 2026
short_interest
FTD: DFTX — 32,345 shares ($0.7M) failed to deliver
Settlement: 20260406, Price: $20.68, FTD Value: $668,894.6, DEFINIUM THERAPEUTICS INC COM
Apr 2, 2026
short_interest
FTD: DFTX — 33,671 shares ($0.7M) failed to deliver
Settlement: 20260402, Price: $20.60, FTD Value: $693,622.6, DEFINIUM THERAPEUTICS INC COM
Mar 24, 2026
short_volume
Short Volume: DFTX — 63.8% short (0.4M / 0.6M)
Short: 375,031 | Exempt: 457 | TRF Vol: 587,396 | Short Ratio: 63.8% | Off-exchange volume (dark pool + OTC)
Mar 23, 2026
short_interest
FTD: DFTX — 160,815 shares ($3.0M) failed to deliver
Settlement: 20260323, Price: $18.40, FTD Value: $2,958,996, DEFINIUM THERAPEUTICS INC COM
Feb 26, 2026
earnings_calendar
DFTX Q4 2025 Earnings After Market Close — 2026-02-26