ARWR

ARROWHEAD PHARMACEUTICALS, INC.

Nasdaq · Pharmaceutical Preparations · Inc. DE · CIK 0000879407
$74.52 +0.15% $10.5B
Insider Selling Cluster (3 insiders)33 New Institutional Positions17 Institutional Exits
Vol
Market Cap$10.5B
Cap SizeLarge Cap
Analyst ConsensusStrong Buy (85%)
Inst. Holders50 funds
Inst. Value$5.6B
Inst. Activity33 buys / 17 sells
Insider Activity0B / 4S
Insider Net $-$1.8M
Exchange Nasdaq·Sector Pharmaceutical Preparations·Inc. DE·CIK 0000879407·Prev Close $74.41

Recent Activity

Jun 10, 2026 short_volume
Short Volume: ARWR — 63.7% short (0.3M / 0.5M)
Short: 320,921 | Exempt: 89 | TRF Vol: 503,800 | Short Ratio: 63.7% | Off-exchange volume (dark pool
May 12, 2026 Insider
Lu Hongbo sold 2,970 shares
Director @ $76.88 ($228.3K)
Apr 23, 2026 Insider
Hamilton James C sold 10,000 shares
Chief Medical Officer @ $75.00 ($750.0K)
Apr 22, 2026 Insider
Apel Daniel Joseph sold 3,208 shares
Chief Financial Officer @ $70.11 ($224.9K)
Inst.
FRED ALGER MANAGEMENT, LLC — ADD
3,342,493 shares ($209.6M)
Inst.
Invesco Ltd. — DOUBLED
3,280,647 shares ($205.7M)

Price Targets

$88.17 +18.3% upside Buy
Current $74.52 Low $46.00 Median $91.50 High $110.00 12 analysts
$46.00 $110.00

Analyst Ratings

Strong Buy85% buy · 20 analysts
4Strong Buy
13Buy
3Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
May 13, 2026 Bernstein MAINTAIN Market Perform → Market Perform
May 8, 2026 RBC Capital MAINTAIN Outperform → Outperform
May 1, 2026 JP Morgan INITIATE Overweight
Apr 21, 2026 Morgan Stanley UPGRADE Equal-Weight → Overweight
Mar 25, 2026 HC Wainwright & Co. REITERATE Buy → Buy

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-1.20 ▲ +5.7% $-1.53 — $-0.26 5% YoY 11
Next Q $-1.13 ▲ +3.1% $-1.58 — $-0.35 -525% YoY 11
Current FY $-3.00 ▲ +7.4% $-3.82 — $-1.73 -29927% YoY 11
Next FY $-4.34 ▼ -1.5% $-6.70 — $-1.81 -45% YoY 11

Top Institutional Holders

FundValueMove
NOMURA ASSET MANAGEMENT CO
BlackRock, Inc.$1.1B
Avoro Capital Advisors LLC$670.9M
FMR LLC$455.6M
VANGUARD PORTFOLIO MANAGEMENT LLC$448.1M

Recent Insider Trades

DateInsiderTypeValue
May 12, 2026Lu HongboSELL$228.3K
Apr 23, 2026Hamilton JamesSELL$750.0K
Apr 22, 2026Apel DanielSELL$224.9K
Mar 5, 2026Hamilton JamesSELL$641.9K
50 institutional holders with $5.6B total value (88,696,745 shares) as of 2026-Q1. Top holders: NOMURA, BlackRock,, Avoro. Net buying activity: 33 institutions added/increased vs 17 reduced.

Top Institutional Holders — 2026-Q1

#FundSharesValue% of TrackedLast Move
1NOMURA ASSET MANAGEMENT CO LTD$0.000.0%
2BlackRock, Inc.18,161,519$1.1B20.5%
3Avoro Capital Advisors LLC10,699,999$670.9M12.1%
4FMR LLC7,266,652$455.6M8.2%
5VANGUARD PORTFOLIO MANAGEMENT LLC7,146,136$448.1M8.1%
6STATE STREET CORP6,496,130$407.3M7.3%
7VANGUARD CAPITAL MANAGEMENT LLC6,032,416$378.2M6.8%
8FRED ALGER MANAGEMENT, LLC3,342,493$209.6M3.8%ADD +82.4%
9Invesco Ltd.3,280,647$205.7M3.7%DOUBLED +498.9%
10BAKER BROS. ADVISORS LP1,992,783$124.9M2.2%
11GOLDMAN SACHS GROUP INC1,739,923$109.1M2.0%
12JANUS HENDERSON GROUP PLC1,436,990$90.1M1.6%
13Pictet Asset Management Holding SA1,273,266$79.6M1.4%
14CHARLES SCHWAB INVESTMENT MANAGEMENT INC1,192,085$74.7M1.3%
15DRIEHAUS CAPITAL MANAGEMENT LLC1,190,335$74.6M1.3%TRIM -32.7%
16D. E. Shaw & Co., Inc.1,183,838$74.2M1.3%
17BANK OF AMERICA CORP /DE/1,064,455$66.7M1.2%ADD +71.1%
18Hood River Capital Management LLC1,056,534$66.2M1.2%NEW
19RENAISSANCE TECHNOLOGIES LLC1,036,495$65.0M1.2%NEW
20VANGUARD FIDUCIARY TRUST CO965,775$60.6M1.1%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
FRED ALGER MANAGEMENT, LLCADD1,832,9973,342,493+82.4%$209.6M2026-Q1
Invesco Ltd.DOUBLED547,7583,280,647+498.9%$205.7M2026-Q1
DRIEHAUS CAPITAL MANAGEMENT LLCTRIM1,769,3401,190,335-32.7%$74.6M2026-Q1
BANK OF AMERICA CORP /DE/ADD622,0291,064,455+71.1%$66.7M2026-Q1
Hood River Capital Management LLCNEW1,056,534$66.2M2026-Q1
RENAISSANCE TECHNOLOGIES LLCNEW1,036,495$65.0M2026-Q1
MORGAN STANLEYTRIM1,476,005960,507-34.9%$60.2M2026-Q1
Connor, Clark & Lunn Investment Management Ltd.ADD663,262836,981+26.2%$52.5M2026-Q1
VOYA INVESTMENT MANAGEMENT LLCADD422,731656,129+55.2%$41.1M2026-Q1
DIMENSIONAL FUND ADVISORS LPDOUBLED147,412608,531+312.8%$38.1M2026-Q1
ARROWSTREET CAPITAL, LIMITED PARTNERSHIPTRIM2,087,953587,125-71.9%$36.8M2026-Q1
Nuveen, LLCADD288,578499,837+73.2%$31.3M2026-Q1
Alyeska Investment Group, L.P.ADD375,371472,870+26.0%$29.6M2026-Q1
FRANKLIN RESOURCES INCDOUBLED107,366462,707+331.0%$29.0M2026-Q1
PANAGORA ASSET MANAGEMENT INCDOUBLED35,955461,193+1182.7%$28.9M2026-Q1
CANADA PENSION PLAN INVESTMENT BOARDDOUBLED28,600325,700+1038.8%$20.4M2026-Q1
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEMNEW257,133$16.1M2026-Q1
Legal & General Group PlcTRIM395,311229,097-42.0%$14.4M2026-Q1
BALYASNY ASSET MANAGEMENT L.P.TRIM376,216206,412-45.1%$12.9M2026-Q1
Neuberger Berman Group LLCDOUBLED100,385203,914+103.1%$12.8M2026-Q1
SEI INVESTMENTS COADD112,279203,220+81.0%$12.7M2026-Q1
Woodline Partners LPTRIM400,184200,184-50.0%$12.6M2026-Q1
AMERIPRISE FINANCIAL INCTRIM257,477191,054-25.8%$12.0M2026-Q1
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLCDOUBLED15,802184,304+1066.3%$11.6M2026-Q1
MARSHALL WACE, LLPADD123,855179,573+45.0%$11.3M2026-Q1
3 unique insiders with 4 transactions. Net insider value: -$1.8M ($0.00 bought, $1.8M sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
May 12, 2026Lu HongboDirectorSELL2,970$76.88$228.3K
Apr 23, 2026Hamilton James CChief Medical OfficerSELL10,000$75.00$750.0K
Apr 22, 2026Apel Daniel JosephChief Financial OfficerSELL3,208$70.11$224.9K
Mar 5, 2026Hamilton James CChief Medical OfficerSELL10,000$64.19$641.9K

No SEC filing reports analyzed yet. Reports are generated when new filings are detected and processed by the LLM pipeline.

No press releases analyzed yet. Press releases are collected from GlobeNewsWire and analyzed by the LLM pipeline.

Current analyst consensus: Strong Buy (85% buy). Based on 20 analysts: 4 strong buy, 13 buy, 3 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$88.17 mean target +18.3% upside Buy (1.62)
$46.00 Low $110.00 High
MetricValue
Current Price$74.52
Target Low$46.00
Target Mean$88.17
Target Median$91.50
Target High$110.00
# Analysts12
RecommendationBuy (1.62)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-1.20 $-1.53 $-0.26 4.6% +5.7% 7↑ 2↓ $0.0B 68.1% 11
Next Q
2026-09-30
$-1.13 $-1.58 $-0.35 -525.3% +3.1% 4↑ 3↓ $0.1B -69.3% 11
Current FY
2026-09-30
$-3.00 $-3.82 $-1.73 -29927.3% +7.4% 7↑ 3↓ $0.4B -46.5% 11
Next FY
2027-09-30
$-4.34 $-6.70 $-1.81 -44.5% -1.5% 4↑ 5↓ $0.3B -24.2% 11

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-1.202
7d ago$-1.202-0.000
30d ago$-1.274+0.072
60d ago$-1.369+0.167
90d ago$-1.369+0.167
9 analyst firms have rated this stock: 1 upgrades, 0 downgrades, 1 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
May 13, 2026 Bernstein MAINTAIN Market Perform Market Perform
May 8, 2026 RBC Capital MAINTAIN Outperform Outperform
May 1, 2026 JP Morgan INITIATE Overweight
Apr 21, 2026 Morgan Stanley UPGRADE Equal-Weight Overweight
Mar 25, 2026 HC Wainwright & Co. REITERATE Buy Buy
Feb 10, 2026 HC Wainwright & Co. REITERATE Buy Buy
Jan 22, 2026 B. Riley Securities MAINTAIN Buy Buy
Jan 21, 2026 HC Wainwright & Co. MAINTAIN Buy Buy
Jan 13, 2026 Piper Sandler REITERATE Overweight Overweight
Jan 7, 2026 Goldman Sachs MAINTAIN Neutral Neutral
Jan 7, 2026 Morgan Stanley MAINTAIN Equal-Weight Equal-Weight
Jan 7, 2026 Chardan Capital MAINTAIN Buy Buy
Dec 17, 2025 Piper Sandler MAINTAIN Overweight Overweight

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 202641330085%
May 1, 202641230084%
Apr 1, 202641140079%
Mar 1, 202641140079%
Feb 1, 202641150075%
Jan 1, 202641150075%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

No Reddit sentiment data available yet. Sentiment is analyzed from Reddit investment communities on a rolling basis.

Jun 10, 2026
short_volume
Short Volume: ARWR — 63.7% short (0.3M / 0.5M)
Short: 320,921 | Exempt: 89 | TRF Vol: 503,800 | Short Ratio: 63.7% | Off-exchange volume (dark pool + OTC)
Jun 9, 2026
short_volume
Short Volume: ARWR — 59.7% short (0.3M / 0.6M)
Short: 334,615 | Exempt: 2,753 | TRF Vol: 560,293 | Short Ratio: 59.7% | Off-exchange volume (dark pool + OTC)
Jun 5, 2026
Clinical Trial
Study of ARO-APOC3 (Plozasiran) in Adults With Familial Chylomicronemia Syndrome (FCS)
Phase Phase 3 — COMPLETED
Jun 3, 2026
short_volume
Short Volume: ARWR — 55.4% short (0.3M / 0.5M)
Short: 299,984 | Exempt: 35 | TRF Vol: 541,184 | Short Ratio: 55.4% | Off-exchange volume (dark pool + OTC)
Jun 2, 2026
short_volume
Short Volume: ARWR — 65.4% short (0.5M / 0.7M)
Short: 462,252 | Exempt: 0 | TRF Vol: 707,120 | Short Ratio: 65.4% | Off-exchange volume (dark pool + OTC)
May 30, 2026
Clinical Trial
Study of ARO-C3 in Adult Healthy Volunteers and Patients With Complement Mediated Renal Disease
Phase Phase 2 — COMPLETED
May 27, 2026
short_volume
Short Volume: ARWR — 76.3% short (0.4M / 0.6M)
Short: 432,855 | Exempt: 0 | TRF Vol: 567,677 | Short Ratio: 76.3% | Off-exchange volume (dark pool + OTC)
May 26, 2026
short_volume
Short Volume: ARWR — 75.3% short (0.5M / 0.6M)
Short: 458,781 | Exempt: 0 | TRF Vol: 609,261 | Short Ratio: 75.3% | Off-exchange volume (dark pool + OTC)
May 23, 2026
Clinical Trial
Study of ARO-ANG3 in Participants With Homozygous Familial Hypercholesterolemia (HOFH)
Phase Phase 2 — TERMINATED
May 21, 2026
short_volume
Short Volume: ARWR — 57.8% short (0.4M / 0.7M)
Short: 419,619 | Exempt: 605 | TRF Vol: 726,365 | Short Ratio: 57.8% | Off-exchange volume (dark pool + OTC)
May 20, 2026
short_volume
Short Volume: ARWR — 84.5% short (0.5M / 0.6M)
Short: 467,291 | Exempt: 0 | TRF Vol: 552,865 | Short Ratio: 84.5% | Off-exchange volume (dark pool + OTC)
May 19, 2026
short_volume
Short Volume: ARWR — 80.0% short (0.7M / 0.9M)
Short: 735,786 | Exempt: 209 | TRF Vol: 919,844 | Short Ratio: 80.0% | Off-exchange volume (dark pool + OTC)
May 18, 2026
short_volume
Short Volume: ARWR — 79.5% short (0.5M / 0.6M)
Short: 492,783 | Exempt: 733 | TRF Vol: 619,670 | Short Ratio: 79.5% | Off-exchange volume (dark pool + OTC)
May 15, 2026
short_volume
Short Volume: ARWR — 73.7% short (0.4M / 0.6M)
Short: 446,659 | Exempt: 228 | TRF Vol: 605,688 | Short Ratio: 73.7% | Off-exchange volume (dark pool + OTC)
May 14, 2026
short_volume
Short Volume: ARWR — 69.8% short (0.4M / 0.6M)
Short: 439,055 | Exempt: 330 | TRF Vol: 629,055 | Short Ratio: 69.8% | Off-exchange volume (dark pool + OTC)
May 13, 2026
Clinical Trial
Study of ARO-APOC3 in Adults With Dyslipidemia
Phase Phase 2 — COMPLETED
May 13, 2026
short_volume
Short Volume: ARWR — 77.4% short (0.5M / 0.6M)
Short: 485,040 | Exempt: 598 | TRF Vol: 626,337 | Short Ratio: 77.4% | Off-exchange volume (dark pool + OTC)
May 12, 2026
short_volume
Short Volume: ARWR — 74.3% short (0.5M / 0.6M)
Short: 482,346 | Exempt: 908 | TRF Vol: 648,844 | Short Ratio: 74.3% | Off-exchange volume (dark pool + OTC)
May 11, 2026
short_volume
Short Volume: ARWR — 62.3% short (0.6M / 0.9M)
Short: 561,250 | Exempt: 128 | TRF Vol: 901,559 | Short Ratio: 62.3% | Off-exchange volume (dark pool + OTC)
Apr 14, 2026
Clinical Trial
Study of Plozasiran (ARO-APOC3) in Adults With Mixed Dyslipidemia
Phase Phase 2 — COMPLETED