APLS

Apellis Pharmaceuticals, Inc.

Nasdaq · Pharmaceutical Preparations · Inc. DE · CIK 0001492422
High Impact Filing (8/10)32 New Institutional Positions18 Institutional Exits
Vol
Inst. Holders50 funds
Inst. Value$3.7B
Inst. Activity32 buys / 18 sells
SEC Reports5
Exchange Nasdaq·Sector Pharmaceutical Preparations·Inc. DE·CIK 0001492422

Recent Activity

May 26, 2026 SEC
Apellis Pharmaceuticals filed Form 15-12G to terminate its SEC registration and suspend reporting obligations, effective
15-12G — Impact 6/10
May 14, 2026 SEC
Nasdaq filed a Form 25-NSE to remove Apellis Pharmaceuticals' common stock from listing and registration, effective May
25-NSE — Impact 2/10
May 14, 2026 SEC
Biogen completed its acquisition of Apellis Pharmaceuticals on May 14, 2026, through a tender offer and subsequent merge
8-K — Impact 8/10
May 14, 2026 Insider
WHEELER CRAIG A disposed of 24,444 shares
Director
May 14, 2026 Insider
WHEELER CRAIG A disposed of 15,110 shares
Director
May 14, 2026 Insider
Baumal Caroline disposed of 82,500 shares
Chief Medical Officer
Inst.
BlackRock, Inc. — DOUBLED
13,536,964 shares ($544.6M)
Inst.
STATE STREET CORP — ADD
6,844,990 shares ($275.4M)

Price Targets

Historical data — last covering-analyst action Oct 2024. No current recommendation available.
$40.92 (Oct 2024)
Current $41.03 Low $40.00 Median $41.00 High $41.00 13 analysts
$40.00 $41.00

Analyst Ratings

Historical distribution30% buy · 27 analysts · last covering-analyst action Oct 2024
3Strong Buy
5Buy
19Hold
0Sell
0Strong Sell
Historical Analyst Actions
DateFirmActionRating
Oct 16, 2024 Scotiabank INITIATE Sector Perform
Oct 16, 2024 William Blair INITIATE Outperform
Sep 24, 2024 Wells Fargo MAINTAIN Equal-Weight → Equal-Weight
Sep 23, 2024 Baird MAINTAIN Outperform → Outperform
Sep 20, 2024 Mizuho MAINTAIN Neutral → Neutral

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-0.32 ▲ +3.5% $-0.49 — $-0.16 4% YoY 8
Next Q $-0.28 ▼ -6.2% $-0.60 — $-0.10 -117% YoY 8
Current FY $-1.17 ▼ -4.1% $-2.19 — $-0.38 -687% YoY 8
Next FY $-0.31 ▼ -28.7% $-2.02 — $0.68 73% YoY 7

Top Institutional Holders

FundValueMove
Clear Street Group Inc.
BlackRock, Inc.$544.6MDOUBLED
Avoro Capital Advisors LLC$491.7M
MORGAN STANLEY$404.0M
STATE STREET CORP$275.4MADD

Recent Insider Trades

DateInsiderTypeValue
May 14, 2026WHEELER CRAIGU$0.00
May 14, 2026WHEELER CRAIGD$0.00
May 14, 2026Baumal CarolineD$0.00
May 14, 2026Walbert KeliD$0.00
May 14, 2026Chan GeraldU$0.00
50 institutional holders with $3.7B total value (93,390,987 shares) as of 2026-Q1. Top holders: Clear, BlackRock,, Avoro. Net buying activity: 32 institutions added/increased vs 18 reduced.

Top Institutional Holders — 2026-Q1

#FundSharesValue% of TrackedLast Move
1Clear Street Group Inc.350,000$0.000.0%
2BlackRock, Inc.13,536,964$544.6M14.6%DOUBLED +116.2%
3Avoro Capital Advisors LLC12,222,222$491.7M13.2%
4MORGAN STANLEY10,042,399$404.0M10.8%
5STATE STREET CORP6,844,990$275.4M7.4%ADD +48.4%
6VANGUARD PORTFOLIO MANAGEMENT LLC5,404,559$217.4M5.8%
7Pentwater Capital Management LP5,250,000$211.2M5.7%NEW
8VANGUARD CAPITAL MANAGEMENT LLC4,768,944$191.9M5.2%
9Point72 Asset Management, L.P.4,183,918$168.3M4.5%DOUBLED +600.0%
10RTW INVESTMENTS, LP3,685,045$148.2M4.0%TRIM -51.9%
11GOLDMAN SACHS GROUP INC1,980,144$79.7M2.1%
12BALYASNY ASSET MANAGEMENT L.P.1,917,501$77.1M2.1%DOUBLED +2844.0%
13DIMENSIONAL FUND ADVISORS LP1,338,995$53.7M1.4%DOUBLED +640.1%
14TORONTO DOMINION BANK1,236,436$49.7M1.3%NEW
15HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND1,202,100$48.4M1.3%NEW
16BANK OF AMERICA CORP /DE/1,190,864$47.9M1.3%
17Hudson Bay Capital Management LP1,190,416$47.9M1.3%
18FIL Ltd1,140,000$45.9M1.2%NEW
19SOROS FUND MANAGEMENT LLC1,056,000$42.5M1.1%NEW
20CAPITOLIS LIQUID GLOBAL MARKETS LLC1,013,500$40.8M1.1%NEW

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
BlackRock, Inc.DOUBLED6,260,11313,536,964+116.2%$544.6M2026-Q1
STATE STREET CORPADD4,613,4466,844,990+48.4%$275.4M2026-Q1
Pentwater Capital Management LPNEW5,250,000$211.2M2026-Q1
Point72 Asset Management, L.P.DOUBLED597,6724,183,918+600.0%$168.3M2026-Q1
RTW INVESTMENTS, LPTRIM7,666,7643,685,045-51.9%$148.2M2026-Q1
BALYASNY ASSET MANAGEMENT L.P.DOUBLED65,1331,917,501+2844.0%$77.1M2026-Q1
DIMENSIONAL FUND ADVISORS LPDOUBLED180,9251,338,995+640.1%$53.7M2026-Q1
TORONTO DOMINION BANKNEW1,236,436$49.7M2026-Q1
HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUNDNEW1,202,100$48.4M2026-Q1
FIL LtdNEW1,140,000$45.9M2026-Q1
SOROS FUND MANAGEMENT LLCNEW1,056,000$42.5M2026-Q1
CAPITOLIS LIQUID GLOBAL MARKETS LLCNEW1,013,500$40.8M2026-Q1
Woodline Partners LPADD542,981976,175+79.8%$39.3M2026-Q1
RENAISSANCE TECHNOLOGIES LLCADD633,058935,958+47.8%$37.7M2026-Q1
FIRST TRUST ADVISORS LPADD495,947903,637+82.2%$36.4M2026-Q1
Magnetar Financial LLCNEW869,229$35.0M2026-Q1
TUDOR INVESTMENT CORP ET ALDOUBLED215,000650,000+202.3%$26.1M2026-Q1
Invesco Ltd.ADD225,976437,868+93.8%$17.6M2026-Q1
LMR Partners LLPNEW403,622$16.2M2026-Q1
Verition Fund Management LLCNEW400,000$16.1M2026-Q1
PUBLIC SECTOR PENSION INVESTMENT BOARDNEW366,674$14.8M2026-Q1
GABELLI FUNDS LLCNEW321,200$12.9M2026-Q1
RHUMBLINE ADVISERSDOUBLED116,917275,540+135.7%$11.1M2026-Q1
CAPSTONE INVESTMENT ADVISORS, LLCNEW250,000$10.1M2026-Q1
WELLINGTON MANAGEMENT GROUP LLPNEAR_EXIT12,721,352249,635-98.0%$10.0M2026-Q1
15 unique insiders with 50 transactions. Net insider value: $0.00 ($0.00 bought, $0.00 sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
May 14, 2026WHEELER CRAIG ADirectorU24,444
May 14, 2026WHEELER CRAIG ADirectorD15,110
May 14, 2026Baumal CarolineChief Medical OfficerD82,500
May 14, 2026Walbert KeliDirectorD8,332
May 14, 2026Chan GeraldDirectorU25,666
May 14, 2026Baumal CarolineChief Medical OfficerU86,525
May 14, 2026Baumal CarolineChief Medical OfficerAWARD41,250
May 14, 2026Baumal CarolineChief Medical OfficerD41,250
May 14, 2026Francois CedricChief Executive OfficerU425,968
May 14, 2026Chan GeraldDirectorD3,062
May 14, 2026Machiels AlecDirectorU384,989
May 14, 2026Francois CedricChief Executive OfficerAWARD143,750
May 14, 2026Francois CedricChief Executive OfficerD143,750
May 14, 2026Watson David O.General CounselU144,517
May 14, 2026Francois CedricChief Executive OfficerD100,538
May 14, 2026Watson David O.General CounselAWARD41,250
May 14, 2026Watson David O.General CounselD41,250
May 14, 2026Watson David O.General CounselD82,500
May 14, 2026WHEELER CRAIG ADirectorD28,195
May 14, 2026Boucher KelleyChief People OfficerU127,804
May 14, 2026Boucher KelleyChief People OfficerAWARD15,073
May 14, 2026Boucher KelleyChief People OfficerD15,073
May 14, 2026Boucher KelleyChief People OfficerD32,976
May 14, 2026O'Brien Stephanie MonaghanDirectorU25,666
May 14, 2026O'Brien Stephanie MonaghanDirectorD3,062
May 14, 2026O'Brien Stephanie MonaghanDirectorD17,580
May 14, 2026DeLong Mark JeffreyChief Business & Strat OfficerU114,591
May 14, 2026DeLong Mark JeffreyChief Business & Strat OfficerAWARD41,250
May 14, 2026DeLong Mark JeffreyChief Business & Strat OfficerD41,250
May 14, 2026DeLong Mark JeffreyChief Business & Strat OfficerD82,500
May 14, 2026Walbert KeliDirectorU17,051
May 14, 2026Walbert KeliDirectorD14,684
May 14, 2026Nicholson NurChief Technical OfficerU116,338
May 14, 2026Nicholson NurChief Technical OfficerAWARD22,610
May 14, 2026Nicholson NurChief Technical OfficerD22,610
May 14, 2026Nicholson NurChief Technical OfficerD82,500
May 14, 2026Chan GeraldDirectorD17,580
May 14, 2026Chopas James GeorgeVP/Chief Accounting OfficerAWARD5,625
May 14, 2026Deschatelets PascalChief Scientific OfficerU1,177,222
May 14, 2026Deschatelets PascalChief Scientific OfficerAWARD41,250
May 14, 2026Deschatelets PascalChief Scientific OfficerD41,250
May 14, 2026Deschatelets PascalChief Scientific OfficerD108,622
May 14, 2026Machiels AlecDirectorD3,062
May 14, 2026Machiels AlecDirectorD17,580
May 14, 2026Sullivan Timothy EugeneChief Financial OfficerU140,945
May 14, 2026Sullivan Timothy EugeneChief Financial OfficerAWARD41,250
May 14, 2026Sullivan Timothy EugeneChief Financial OfficerD41,250
May 14, 2026Sullivan Timothy EugeneChief Financial OfficerD232,903
May 14, 2026FONTEYNE PAUL R.DirectorU30,666
May 14, 2026FONTEYNE PAUL R.DirectorD3,062

No press releases analyzed yet. Press releases are collected from GlobeNewsWire and analyzed by the LLM pipeline.

Historical analyst distribution (last covering-analyst action Oct 2024): 30% buy across 27 analysts — 3 strong buy, 5 buy, 19 hold, 0 sell, 0 strong sell. No current recommendation available.

Analyst Price Targets

Historical data — last covering-analyst action Oct 2024. No current recommendation available.
$40.92 mean target (Oct 2024)
$40.00 Low $41.00 High
MetricValue
Current Price$41.03
Target Low$40.00
Target Mean$40.92
Target Median$41.00
Target High$41.00
# Analysts13
Recommendation— (no recent coverage)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-0.32 $-0.49 $-0.16 3.8% +3.5% 0↑ 2↓ $0.2B 17.6% 8
Next Q
2026-09-30
$-0.28 $-0.60 $-0.10 -116.8% -6.2% 1↑ 1↓ $0.2B -52.2% 8
Current FY
2026-12-31
$-1.17 $-2.19 $-0.38 -686.9% -4.1% 2↑ 1↓ $0.9B -7.9% 8
Next FY
2027-12-31
$-0.31 $-2.02 $0.68 73.2% -28.7% 3↑ 2↓ $1.0B 11.2% 7

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-0.318
7d ago$-0.329+0.012
30d ago$-0.329+0.012
60d ago$-0.309-0.008
90d ago$-0.353+0.035
16 analyst firms have rated this stock: 1 upgrades, 0 downgrades, 3 initiations.

Historical Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
Oct 16, 2024 Scotiabank INITIATE Sector Perform
Oct 16, 2024 William Blair INITIATE Outperform
Sep 24, 2024 Wells Fargo MAINTAIN Equal-Weight Equal-Weight
Sep 23, 2024 Baird MAINTAIN Outperform Outperform
Sep 20, 2024 Mizuho MAINTAIN Neutral Neutral
Sep 20, 2024 Needham REITERATE Buy Buy
Sep 13, 2024 JP Morgan MAINTAIN Overweight Overweight
Aug 13, 2024 JP Morgan MAINTAIN Overweight Overweight
Aug 9, 2024 UBS MAINTAIN Buy Buy
Aug 9, 2024 Wedbush MAINTAIN Neutral Neutral
Aug 9, 2024 Goldman Sachs MAINTAIN Buy Buy
Aug 9, 2024 Baird MAINTAIN Outperform Outperform
Aug 9, 2024 Needham REITERATE Buy Buy
Aug 2, 2024 HC Wainwright & Co. MAINTAIN Buy Buy
Aug 2, 2024 Goldman Sachs MAINTAIN Buy Buy
Aug 2, 2024 Needham REITERATE Buy Buy
Jul 31, 2024 Jefferies MAINTAIN Buy Buy
Jul 26, 2024 Baird MAINTAIN Outperform Outperform
Jul 23, 2024 Baird MAINTAIN Outperform Outperform
Jul 17, 2024 Goldman Sachs MAINTAIN Buy Buy
Jun 28, 2024 Baird MAINTAIN Outperform Outperform
May 31, 2024 Piper Sandler INITIATE Neutral
May 28, 2024 HC Wainwright & Co. REITERATE Buy Buy
May 23, 2024 Wells Fargo MAINTAIN Equal-Weight Equal-Weight
May 8, 2024 Citigroup MAINTAIN Buy Buy
May 8, 2024 HC Wainwright & Co. REITERATE Buy Buy
May 8, 2024 UBS MAINTAIN Buy Buy
May 8, 2024 Needham REITERATE Buy Buy
Apr 29, 2024 Mizuho MAINTAIN Neutral Neutral
Apr 26, 2024 HC Wainwright & Co. REITERATE Buy Buy
Apr 25, 2024 Needham REITERATE Buy Buy
Apr 17, 2024 Wedbush MAINTAIN Neutral Neutral
Apr 15, 2024 HC Wainwright & Co. REITERATE Buy Buy
Apr 9, 2024 Needham REITERATE Buy Buy
Mar 27, 2024 Mizuho MAINTAIN Neutral Neutral
Mar 6, 2024 JP Morgan MAINTAIN Overweight Overweight
Mar 4, 2024 UBS MAINTAIN Buy Buy
Feb 28, 2024 HC Wainwright & Co. REITERATE Buy Buy
Feb 28, 2024 Wedbush MAINTAIN Neutral Neutral
Feb 16, 2024 Mizuho MAINTAIN Neutral Neutral
Feb 6, 2024 Baird REITERATE Outperform Outperform
Feb 5, 2024 Jefferies UPGRADE Hold Buy
Jan 30, 2024 Oppenheimer MAINTAIN Outperform Outperform
Jan 24, 2024 Needham MAINTAIN Buy Buy
Jan 17, 2024 Baird MAINTAIN Outperform Outperform
Jan 17, 2024 HC Wainwright & Co. MAINTAIN Buy Buy
Jan 12, 2024 Wedbush MAINTAIN Neutral Neutral
Jan 11, 2024 Raymond James MAINTAIN Strong Buy Strong Buy
Jan 9, 2024 Goldman Sachs MAINTAIN Buy Buy
Dec 15, 2023 Citigroup MAINTAIN Buy Buy

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 202635190030%
May 1, 202635190030%
Apr 1, 202639150044%
Mar 1, 202681281069%
Feb 1, 202681271071%
Jan 1, 202671281068%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

Recent Reddit Threads

r/investing Bullish 2mo ago
Market Close Report - Tuesday, March 31, 2026
▲ 1 💬 0 ⚡ 0.5
Jun 5, 2026
Clinical Trial
Pegcetacoplan Long Term Safety and Efficacy Extension Study
Phase Phase 3 — COMPLETED
May 11, 2026
dark_pool
Dark Pool: APLS — 13.4M shares, 34,348 trades
Week starting 2026-05-11. Total ATS volume: 13,393,774 shares across 34,348 trades.
May 5, 2026
earnings_calendar
APLS Q1 2026 Earnings Scheduled — 2026-05-05
May 4, 2026
short_interest
FTD: APLS — 33,636 shares ($1.4M) failed to deliver
Settlement: 20260504, Price: $40.96, FTD Value: $1,377,730.56, APELLIS PHARMACEUTICALS INC CO
May 4, 2026
dark_pool
Dark Pool: APLS — 4.4M shares, 25,576 trades
Week starting 2026-05-04. Total ATS volume: 4,377,894 shares across 25,576 trades.
Apr 30, 2026
earnings_calendar
APLS Q1 2026 Earnings Scheduled — 2026-04-30
Apr 30, 2026
short_interest
FTD: APLS — 28,566 shares ($1.2M) failed to deliver
Settlement: 20260430, Price: $40.95, FTD Value: $1,169,777.7, APELLIS PHARMACEUTICALS INC CO
Apr 29, 2026
short_interest
FTD: APLS — 555,013 shares ($22.7M) failed to deliver
Settlement: 20260429, Price: $40.99, FTD Value: $22,749,982.87, APELLIS PHARMACEUTICALS INC CO
Apr 27, 2026
dark_pool
Dark Pool: APLS — 1.9M shares, 22,743 trades
Week starting 2026-04-27. Total ATS volume: 1,928,228 shares across 22,743 trades.
Apr 24, 2026
short_volume
Short Volume: APLS — 55.0% short (0.3M / 0.6M)
Short: 317,489 | Exempt: 0 | TRF Vol: 577,020 | Short Ratio: 55.0% | Off-exchange volume (dark pool + OTC)
Apr 22, 2026
short_interest
FTD: APLS — 39,752 shares ($1.6M) failed to deliver
Settlement: 20260422, Price: $40.94, FTD Value: $1,627,446.88, APELLIS PHARMACEUTICALS INC CO
Apr 21, 2026
Clinical Trial
Study Assessing the Safety and Efficacy of Pegcetacoplan in Post-Transplant Recurrence of C3G or IC-MPGN
Phase Phase 2 — COMPLETED
Apr 20, 2026
short_interest
FTD: APLS — 14,078 shares ($0.6M) failed to deliver
Settlement: 20260420, Price: $40.90, FTD Value: $575,790.2, APELLIS PHARMACEUTICALS INC CO
Apr 20, 2026
dark_pool
Dark Pool: APLS — 2.4M shares, 21,808 trades
Week starting 2026-04-20. Total ATS volume: 2,399,324 shares across 21,808 trades.
Apr 13, 2026
dark_pool
Dark Pool: APLS — 3.9M shares, 30,619 trades
Week starting 2026-04-13. Total ATS volume: 3,920,540 shares across 30,619 trades.
Apr 13, 2026
short_volume
Short Volume: APLS — 61.5% short (2.1M / 3.3M)
Short: 2,059,937 | Exempt: 134 | TRF Vol: 3,347,152 | Short Ratio: 61.5% | Off-exchange volume (dark pool + OTC)
Apr 7, 2026
short_interest
FTD: APLS — 22,198 shares ($0.9M) failed to deliver
Settlement: 20260407, Price: $40.63, FTD Value: $901,904.74, APELLIS PHARMACEUTICALS INC CO