ANAB

ANAPTYSBIO, INC

Nasdaq · Pharmaceutical Preparations · Inc. DE · CIK 0001370053
$51.36 +1.97% $1.5B
Insider Selling Cluster (2 insiders)High Impact Filing (7/10)3 Institutional Exits
Vol
Market Cap$1.5B
Cap SizeSmall Cap
Analyst ConsensusStrong Buy (94%)
Inst. Holders8 funds
Inst. Value$159.5M
Inst. Activity1 buys / 3 sells
Insider Activity0B / 3S
Insider Net $-$1.3M
Reddit Sentiment50° Neutral
SEC Reports12
Press Releases3
Exchange Nasdaq·Sector Pharmaceutical Preparations·Inc. DE·CIK 0001370053·Prev Close $50.37

Recent Activity

Dec 12, 2026 fda_pdufa
PDUFA: ANAB — imsidolimab in generalized pustular psoriasis (GPP) — 2026-12-12
FDA target action date 2026-12-12 for ANAB (ANAPTYSBIO, INC). Drug: imsidolimab. Indication: general
Jun 8, 2026 SEC
Dennis Mulroy, an officer of AnaptysBio, filed a Form 144 notice of intent to sell 21,987 shares of common stock, with a
144 — Impact 5/10
Jun 5, 2026 SEC
Dennis Mulroy, an officer of AnaptysBio, filed a Form 144 on June 5, 2026, indicating intent to sell 22,491 shares of co
144 — Impact 5/10
Jun 5, 2026 SEC
Dennis Mulroy, an officer of AnaptysBio, filed a Form 144 on June 5, 2026, indicating intent to sell 20,000 common share
144 — Impact 5/10
May 11, 2026 Insider
Hughes Owen sold 11,250 shares
Director @ $0.00 ($0.00)
May 11, 2026 Insider
Murphy Christopher M. sold 25,765 shares
Chief Financial Officer @ $0.00 ($0.00)
Apr 20, 2026 Insider
Faga Daniel sold 11,000 shares
President, CEO @ $0.00 ($0.00)
Inst.
MORGAN STANLEY — TRIM
1,034,562 shares ($50.2M)

Price Targets

$84.45 +63.6% upside Strong Buy
Current $51.63 Low $66.00 Median $78.00 High $140.00 11 analysts
$66.00 $140.00

Analyst Ratings

Strong Buy94% buy · 17 analysts
6Strong Buy
10Buy
1Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
May 13, 2026 UBS MAINTAIN Buy → Buy
May 13, 2026 Barclays MAINTAIN Overweight → Overweight
May 4, 2026 Piper Sandler MAINTAIN Overweight → Overweight
Apr 28, 2026 Leerink Partners MAINTAIN Outperform → Outperform
Apr 22, 2026 Barclays MAINTAIN Overweight → Overweight

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $0.39 ▲ +285.4% $-0.08 — $1.03 129% YoY 4
Next Q $0.47 ▲ +342.9% $-0.08 — $1.29 -10% YoY 5
Current FY $0.37 ▲ +335.5% $-1.93 — $2.49 180% YoY 4
Next FY $5.83 ▲ +389.8% $4.50 — $8.77 1479% YoY 4

Top Institutional Holders

FundValueMove
VANGUARD GROUP INC$74.9M
MORGAN STANLEY$50.2MTRIM
TWO SIGMA INVESTMENTS, LP$12.4M
CHARLES SCHWAB INVESTMENT MANAGEMENT$9.6MADD
BANK OF AMERICA CORP$6.3MNEAR_EXIT

Recent Insider Trades

DateInsiderTypeValue
May 11, 2026Hughes OwenA$0.00
May 11, 2026Murphy ChristopherA$0.00
Apr 20, 2026Faga DanielD$0.00
Apr 20, 2026Faga DanielD$0.00
Apr 20, 2026Faga DanielA$0.00

Reddit Sentiment

50°
Neutral
Bearish Neutral Bullish
1 mentions 0 bullish 0 bearish
8 institutional holders with $159.5M total value (3,290,276 shares) as of 2025-Q4. Top holders: VANGUARD, MORGAN, TWO. Net selling activity: 3 institutions trimmed/exited vs 1 added.

Top Institutional Holders — 2025-Q4

#FundSharesValue% of TrackedLast Move
1VANGUARD GROUP INC1,544,037$74.9M46.9%
2MORGAN STANLEY1,034,562$50.2M31.4%TRIM -33.5%
3TWO SIGMA INVESTMENTS, LP256,635$12.4M7.8%
4CHARLES SCHWAB INVESTMENT MANAGEMENT INC198,660$9.6M6.0%ADD +31.4%
5BANK OF AMERICA CORP /DE/130,767$6.3M4.0%NEAR_EXIT -88.2%
6RENAISSANCE TECHNOLOGIES LLC76,300$3.7M2.3%TRIM -38.1%
7FMR LLC27,108$1.3M0.8%TRIM -49.0%
8WELLS FARGO & COMPANY/MN22,207$1.1M0.7%ADD +61.6%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
MORGAN STANLEYTRIM1,556,2581,034,562-33.5%$50.2M2025-Q4
RENAISSANCE TECHNOLOGIES LLCTRIM123,30076,300-38.1%$3.7M2025-Q4
FMR LLCTRIM53,16227,108-49.0%$1.3M2025-Q4
WELLS FARGO & COMPANY/MNADD13,74322,207+61.6%$1.1M2025-Q4
CHARLES SCHWAB INVESTMENT MANAGEMENT INCADD157,135206,441+31.4%$6.3M2025-Q3
BANK OF AMERICA CORP /DE/NEAR_EXIT1,076,799127,241-88.2%$3.9M2025-Q3
RENAISSANCE TECHNOLOGIES LLCTRIM263,086123,300-53.1%$3.8M2025-Q3
UBS Group AGNEAR_EXIT1,272,49975,262-94.1%$2.3M2025-Q3
FMR LLCTRIM72,11953,162-26.3%$1.6M2025-Q3
WELLS FARGO & COMPANY/MNTRIM33,32813,743-58.8%$420.8K2025-Q3
MORGAN STANLEYDOUBLED504,6361,869,840+270.5%$41.5M2025-Q2
UBS Group AGDOUBLED490,2731,272,499+159.5%$28.2M2025-Q2
FMR LLCNEAR_EXIT1,905,15472,119-96.2%$1.6M2025-Q2
WELLS FARGO & COMPANY/MNDOUBLED11,37733,328+192.9%$739.9K2025-Q2
FMR LLCTRIM3,030,2361,905,154-37.1%$35.4M2025-Q1
MORGAN STANLEYDOUBLED215,917504,636+133.7%$9.4M2025-Q1
UBS Group AGDOUBLED36,606490,273+1239.3%$9.1M2025-Q1
RENAISSANCE TECHNOLOGIES LLCADD193,200338,700+75.3%$6.3M2025-Q1
CITADEL ADVISORS LLCADD273,245398,327+45.8%$5.3M2024-Q4
WELLS FARGO & COMPANY/MNTRIM27,09711,120-59.0%$147.2K2024-Q4
MORGAN STANLEYADD91,768177,382+93.3%$5.9M2024-Q3
CHARLES SCHWAB INVESTMENT MANAGEMENT INCNEW160,321$5.4M2024-Q3
7 unique insiders with 3 transactions. Net insider value: -$1.3M ($0.00 bought, $1.3M sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
May 11, 2026Hughes OwenDirectorA11,250$0.00$0.00
May 11, 2026Murphy Christopher M.Chief Financial OfficerA25,765$0.00$0.00
Apr 20, 2026Faga DanielPresident, CEOD11,000$0.00$0.00
Apr 20, 2026Faga DanielPresident, CEOD11,000$0.00$0.00
Apr 20, 2026Faga DanielPresident, CEOA11,000$0.00$0.00
Apr 20, 2026RENTON HOLLINGSDirectorD15,000$0.00$0.00
Apr 20, 2026RENTON HOLLINGSDirectorA15,000$0.00$0.00
Apr 20, 2026Schmid John P.DirectorD15,000$0.00$0.00
Apr 20, 2026Schmid John P.DirectorA15,000$0.00$0.00
Apr 20, 2026Orwin John ADirectorD3,311$0.00$0.00
Apr 20, 2026Orwin John ADirectorA3,311$0.00$0.00
Mar 30, 2026Schmid John P.DirectorSELL12,596$55.71$701.7K
Mar 27, 2026Faga DanielPresident, CEOSELL510$56.61$28.9K
Mar 25, 2026Faga DanielPresident, CEOA34,300$0.00$0.00
Feb 11, 2026LOUMEAU ERIC JCHIEF LEGAL OFFICERM10,000$0.00$0.00
Feb 11, 2026LOUMEAU ERIC JCHIEF LEGAL OFFICERSELL10,000$54.00$540.0K
Feb 11, 2026LOUMEAU ERIC JCHIEF LEGAL OFFICERM10,000$29.70$297.0K
12 SEC filing reports analyzed. Sentiment: 1 bullish, 8 bearish, 0 mixed, 3 neutral. Avg impact: 4.8/10.
BEARISH 144 5/10
Dennis Mulroy, an officer of AnaptysBio, filed a Form 144 notice of intent to sell 21,987 shares of
Jun 8, 2026
BEARISH 144 5/10
Dennis Mulroy, an officer of AnaptysBio, filed a Form 144 on June 5, 2026, indicating intent to sell
Jun 5, 2026
BEARISH 144 5/10
Dennis Mulroy, an officer of AnaptysBio, filed a Form 144 on June 5, 2026, indicating intent to sell
Jun 5, 2026
BEARISH 144 5/10
Dennis Mulroy, an officer of AnaptysBio, filed a Form 144 notice of intent to sell 10,000 shares of
Jun 5, 2026
BEARISH 144 5/10
CEO Dennis Mulroy filed a Form 144 to sell 20,000 shares (~$1.0M at filing) via a stock option exerc
Jun 3, 2026
BEARISH 144 5/10
Dennis Mulroy, an officer of AnaptysBio, filed a Form 144 on June 1, 2026, indicating intent to sell
Jun 1, 2026
NEUTRAL 8-K 2/10
AnaptysBio filed an 8-K under Item 7.01 to disclose that it has filed Form 8937 with the IRS regardi
May 29, 2026
NEUTRAL 144 3/10
Dennis Mulroy, an officer of AnaptysBio, filed a Form 144 on May 28, 2026, indicating intent to sell
May 28, 2026
BEARISH 144 6/10
CEO Dennis Mulroy filed a Form 144 notice to sell 10,000 shares of AnaptysBio common stock, valued a
May 27, 2026
NEUTRAL 144 3/10
Dennis Mulroy, an officer of AnaptysBio, filed a Form 144 on May 15, 2026, indicating intent to sell
May 15, 2026
BULLISH PRESS-RELEASE 7/10
AnaptysBio reported Q4 2025 EPS of $1.58, a 268% beat vs consensus of -$0.94, indicating strong oper
May 4, 2026
BEARISH CLUSTER 7/10
Two corporate insiders at AnaptysBio sold shares worth $731K within a 7-day window, including CEO Da
Apr 2, 2026
Current analyst consensus: Strong Buy (94% buy). Based on 17 analysts: 6 strong buy, 10 buy, 1 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$84.45 mean target +63.6% upside Strong Buy (1.27)
$66.00 Low $140.00 High
MetricValue
Current Price$51.63
Target Low$66.00
Target Mean$84.45
Target Median$78.00
Target High$140.00
# Analysts11
RecommendationStrong Buy (1.27)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$0.39 $-0.08 $1.03 129.1% +285.4% 0↑ 3↓ $0.0B -15.5% 4
Next Q
2026-09-30
$0.47 $-0.08 $1.29 -10.1% +342.9% 0↑ 3↓ $0.0B -65.9% 5
Current FY
2026-12-31
$0.37 $-1.93 $2.49 180.2% +335.5% 0↑ 3↓ $0.1B -53.2% 4
Next FY
2027-12-31
$5.83 $4.50 $8.77 1479.3% +389.8% 1↑ 2↓ $0.2B 38.4% 4

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$0.389
7d ago$0.427-0.038
30d ago$-0.210+0.599
60d ago$-0.880+1.270
90d ago$-1.036+1.426
8 analyst firms have rated this stock: 0 upgrades, 0 downgrades, 0 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
May 13, 2026 UBS MAINTAIN Buy Buy
May 13, 2026 Barclays MAINTAIN Overweight Overweight
May 4, 2026 Piper Sandler MAINTAIN Overweight Overweight
Apr 28, 2026 Leerink Partners MAINTAIN Outperform Outperform
Apr 22, 2026 Barclays MAINTAIN Overweight Overweight
Apr 21, 2026 UBS MAINTAIN Buy Buy
Mar 31, 2026 Piper Sandler MAINTAIN Overweight Overweight
Mar 30, 2026 HC Wainwright & Co. REITERATE Buy Buy
Mar 17, 2026 UBS MAINTAIN Buy Buy
Mar 12, 2026 Wedbush MAINTAIN Outperform Outperform
Mar 9, 2026 Truist Securities MAINTAIN Hold Hold
Mar 5, 2026 Stifel MAINTAIN Buy Buy
Mar 4, 2026 Barclays MAINTAIN Overweight Overweight
Mar 4, 2026 HC Wainwright & Co. MAINTAIN Buy Buy
Jan 20, 2026 Barclays MAINTAIN Overweight Overweight
Dec 17, 2025 Barclays MAINTAIN Overweight Overweight

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 202661010094%
May 1, 202661020089%
Apr 1, 202671020089%
Mar 1, 202671020089%
Feb 1, 202671020089%
Jan 1, 20267930084%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

50°
Neutral
Bearish Neutral Bullish
1 mentions 0 bullish 0 bearish 1 time period

Reddit Sentiment History

DateMentionsSentimentBullishBearishThreads
Feb 25, 2026156° Neutral001
Dec 12, 2026
fda_pdufa
PDUFA: ANAB — imsidolimab in generalized pustular psoriasis (GPP) — 2026-12-12
FDA target action date 2026-12-12 for ANAB (ANAPTYSBIO, INC). Drug: imsidolimab. Indication: generalized pustular psoriasis (GPP). FDA accepted the BL
May 12, 2026
earnings
Anaptys Announces First Quarter 2026 Financial Results and Provides Business Update
<p>SAN DIEGO, May 12, 2026 (GLOBE NEWSWIRE) -- AnaptysBio, Inc. (Nasdaq: ANAB), a company focused on managing the financial collaborations for <em>J
May 11, 2026
other
Anaptys Appoints Chris Murphy as Chief Financial Officer and Owen Hughes to Board of Directors
<p align="left">SAN DIEGO, May 11, 2026 (GLOBE NEWSWIRE) -- AnaptysBio, Inc. (Nasdaq: ANAB), a company focused on managing the financial collaborati
May 7, 2026
earnings_calendar
ANAB Q1 2026 Earnings After Market Close — 2026-05-07
May 7, 2026
short_volume
Short Volume: ANAB — 55.5% short (0.3M / 0.5M)
Short: 286,023 | Exempt: 0 | TRF Vol: 515,581 | Short Ratio: 55.5% | Off-exchange volume (dark pool + OTC)
May 4, 2026
earnings
Anaptys to Participate at the H.C. Wainwright 2nd Annual Royalty Company Virtual Conference
<p align="left">SAN DIEGO, May 04, 2026 (GLOBE NEWSWIRE) -- AnaptysBio, Inc. (Nasdaq: ANAB), a company focused on managing the financial collaborati
May 4, 2026
earnings_calendar
ANAB Q1 2026 Earnings After Market Close — 2026-05-04
Apr 24, 2026
contract
Delaware Chancery Court Rules in Favor of Anaptys by Dismissing Tesaro’s Anticipatory Breach Claim
<p align="left">SAN DIEGO, April 24, 2026 (GLOBE NEWSWIRE) -- AnaptysBio, Inc. (Nasdaq: ANAB), a company focused on managing the financial collabora
Apr 20, 2026
other
Anaptys Completes Separation of First Tracks Biotherapeutics and Now Exclusively Manages GSK and Vanda Financial Collaborations
<p>SAN DIEGO, April 20, 2026 (GLOBE NEWSWIRE) -- AnaptysBio, Inc. (Nasdaq: ANAB), a royalty management company, today announced the completion of it
Apr 1, 2026
short_interest
FTD: ANAB — 21,487 shares ($1.2M) failed to deliver
Settlement: 20260401, Price: $55.46, FTD Value: $1,191,669.02, ANAPTYSBIO INC COM STK (DE)
Mar 27, 2026
other
Anaptys Board of Directors Approves Spin-Off of First Tracks Biotherapeutics
<p>SAN DIEGO, March 27, 2026 (GLOBE NEWSWIRE) -- AnaptysBio, Inc. (Nasdaq: ANAB) today announced that its Board of Directors has approved the previo
Mar 27, 2026
offering
First Tracks Biotherapeutics, the Planned Spin-Off of Anaptys, Secures Commitments of $145 Million in Private Placement
<p>SAN DIEGO, March 27, 2026 (GLOBE NEWSWIRE) -- AnaptysBio, Inc. (Nasdaq: ANAB) today announced that its planned spin-off, First Tracks Biotherapeu
Mar 27, 2026
buyback
Anaptys Announces $100 Million Stock Repurchase Plan and Provides a Business Update
<p align="left">SAN DIEGO, March 27, 2026 (GLOBE NEWSWIRE) -- AnaptysBio, Inc. (Nasdaq: ANAB) today announced that its Board of Directors has author
Mar 9, 2026
earnings_calendar
ANAB Q4 2025 Earnings After Market Close — 2026-03-09
Mar 3, 2026
earnings
Anaptys Provides Update on Business Separation and Announces Fourth Quarter and Full Year 2025 Financial Results
<p>SAN DIEGO, March 03, 2026 (GLOBE NEWSWIRE) -- AnaptysBio, Inc. (Nasdaq: ANAB), a clinical-stage biotechnology company focused on delivering innov