ALMS

ALUMIS INC.

Nasdaq · Pharmaceutical Preparations · Inc. DE · CIK 0001847367
$20.01 +5.37% $2.4B
4 New Institutional Positions
Vol
Market Cap$2.4B
Cap SizeMid Cap
Analyst ConsensusStrong Buy (88%)
Inst. Holders8 funds
Inst. Value$56.7M
Inst. Activity4 buys / 2 sells
Reddit Sentiment50° Neutral
SEC Reports1
Press Releases2
Exchange Nasdaq·Sector Pharmaceutical Preparations·Inc. DE·CIK 0001847367·Prev Close $18.99

Recent Activity

May 22, 2026 Insider
Drappa Jorn sold 11,317 shares
Chief Medical Officer @ $8.84 ($100.0K)
May 22, 2026 Insider
Drappa Jorn sold 11,317 shares
Chief Medical Officer @ $0.00 ($0.00)
May 18, 2026 SEC
Alumis Inc. filed a DEFA14A soliciting material for its 2026 Annual Meeting, proposing the election of three Class II di
DEFA14A — Impact 3/10
Apr 1, 2026 Insider
Tananbaum James B. sold 1,176,470 shares
Director @ $0.00 ($0.00)
Inst.
MORGAN STANLEY — ADD
506,529 shares ($4.9M)
Inst.
TWO SIGMA INVESTMENTS, LP — DOUBLED
298,219 shares ($2.9M)
Jun 9, 2026 short_volume
Short Volume: ALMS — 84.7% short (0.7M / 0.9M)
Short: 728,623 | Exempt: 5,000 | TRF Vol: 860,164 | Short Ratio: 84.7% | Off-exchange volume (dark p
Mar 28, 2026 Press
Alumis Inc. announced positive Phase 3 results for envudeucitinib, a highly selective oral TYK2 inhibitor, in moderate-t
Impact 8/10

Price Targets

$40.10 +100.4% upside Strong Buy
Current $20.01 Low $25.00 Median $39.50 High $55.00 10 analysts
$25.00 $55.00

Analyst Ratings

Strong Buy88% buy · 17 analysts
8Strong Buy
7Buy
2Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
May 19, 2026 Chardan Capital MAINTAIN Buy → Buy
May 15, 2026 Wells Fargo MAINTAIN Overweight → Overweight
May 15, 2026 Guggenheim MAINTAIN Buy → Buy
May 15, 2026 HC Wainwright & Co. DOWNGRADE Buy → Neutral
Mar 30, 2026 Oppenheimer MAINTAIN Outperform → Outperform

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-0.71 ▲ +4.1% $-0.82 — $-0.55 52% YoY 5
Next Q $-0.72 ▲ +6.4% $-0.79 — $-0.64 32% YoY 5
Current FY $-2.90 ▲ +5.2% $-3.17 — $-2.60 37% YoY 5
Next FY $-2.95 ▲ +8.6% $-3.70 — $-2.22 -2% YoY 5

Top Institutional Holders

FundValueMove
VANGUARD GROUP INC$40.0MDOUBLED
MORGAN STANLEY$4.9MADD
CHARLES SCHWAB INVESTMENT MANAGEMENT$4.9MADD
TWO SIGMA INVESTMENTS, LP$2.9MDOUBLED
BANK OF AMERICA CORP$1.4MTRIM

Recent Insider Trades

DateInsiderTypeValue
May 22, 2026Drappa JornM$100.0K
May 22, 2026Drappa JornM$0.00
Apr 1, 2026Tananbaum JamesJ$0.00
Apr 1, 2026Foresite CapitalJ$0.00
Apr 1, 2026Foresite Labs,J$0.00

Reddit Sentiment

50°
Neutral
Bearish Neutral Bullish
2 mentions 0 bullish 0 bearish
8 institutional holders with $56.7M total value (5,812,089 shares) as of 2025-Q4. Top holders: VANGUARD, MORGAN, CHARLES. Net buying activity: 4 institutions added/increased vs 2 reduced.

Top Institutional Holders — 2025-Q4

#FundSharesValue% of TrackedLast Move
1VANGUARD GROUP INC4,103,290$40.0M70.6%DOUBLED +263.2%
2MORGAN STANLEY506,529$4.9M8.7%ADD +52.4%
3CHARLES SCHWAB INVESTMENT MANAGEMENT INC504,075$4.9M8.7%ADD +29.6%
4TWO SIGMA INVESTMENTS, LP298,219$2.9M5.1%DOUBLED +246.4%
5BANK OF AMERICA CORP /DE/138,341$1.4M2.4%TRIM -47.6%
6WELLS FARGO & COMPANY/MN129,448$1.3M2.2%ADD +45.0%
7RENAISSANCE TECHNOLOGIES LLC108,200$1.1M1.9%TRIM -28.6%
8FMR LLC23,987$234.1K0.4%DOUBLED +246.1%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
MORGAN STANLEYADD332,406506,529+52.4%$4.9M2025-Q4
TWO SIGMA INVESTMENTS, LPDOUBLED86,084298,219+246.4%$2.9M2025-Q4
BANK OF AMERICA CORP /DE/TRIM263,917138,341-47.6%$1.4M2025-Q4
WELLS FARGO & COMPANY/MNADD89,266129,448+45.0%$1.3M2025-Q4
RENAISSANCE TECHNOLOGIES LLCTRIM151,568108,200-28.6%$1.1M2025-Q4
FMR LLCDOUBLED6,93123,987+246.1%$234.1K2025-Q4
UBS Group AGTRIM1,207,555762,675-36.8%$3.0M2025-Q3
CHARLES SCHWAB INVESTMENT MANAGEMENT INCADD378,850491,002+29.6%$2.0M2025-Q3
BANK OF AMERICA CORP /DE/DOUBLED41,693263,917+533.0%$1.1M2025-Q3
RENAISSANCE TECHNOLOGIES LLCTRIM226,815151,568-33.2%$604.8K2025-Q3
WELLS FARGO & COMPANY/MNADD58,39189,266+52.9%$356.2K2025-Q3
TWO SIGMA INVESTMENTS, LPNEW86,084$343.5K2025-Q3
FMR LLCADD4,8406,931+43.2%$27.7K2025-Q3
VANGUARD GROUP INCDOUBLED937,1963,404,211+263.2%$10.2M2025-Q2
UBS Group AGDOUBLED96,1281,207,555+1156.2%$3.6M2025-Q2
CHARLES SCHWAB INVESTMENT MANAGEMENT INCDOUBLED127,854378,850+196.3%$1.1M2025-Q2
MORGAN STANLEYADD228,998339,099+48.1%$1.0M2025-Q2
RENAISSANCE TECHNOLOGIES LLCNEW226,815$680.4K2025-Q2
WELLS FARGO & COMPANY/MNDOUBLED18,05558,391+223.4%$175.2K2025-Q2
BANK OF AMERICA CORP /DE/ADD23,63841,693+76.4%$125.1K2025-Q2
FMR LLCDOUBLED1,6544,840+192.6%$14.5K2025-Q2
TWO SIGMA INVESTMENTS, LPEXIT10,7000-100.0%$0.002025-Q2
MORGAN STANLEYDOUBLED47,321228,998+383.9%$1.4M2025-Q1
UBS Group AGADD48,11896,128+99.8%$590.2K2025-Q1
WELLS FARGO & COMPANY/MNDOUBLED8,77918,055+105.7%$110.9K2025-Q1
4 unique insiders with 0 transactions. Net insider value: $0.00 ($0.00 bought, $0.00 sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
May 22, 2026Drappa JornChief Medical OfficerM11,317$8.84$100.0K
May 22, 2026Drappa JornChief Medical OfficerM11,317$0.00$0.00
Apr 1, 2026Tananbaum James B.DirectorJ1,176,470$0.00$0.00
Apr 1, 2026Foresite Capital Management VI LLC10%+ OwnerJ1,176,470$0.00$0.00
Apr 1, 2026Foresite Labs, LLC10%+ OwnerJ1,176,470$0.00$0.00
1 SEC filing reports analyzed. Sentiment: 0 bullish, 0 bearish, 0 mixed, 1 neutral. Avg impact: 3.0/10.
Current analyst consensus: Strong Buy (88% buy). Based on 17 analysts: 8 strong buy, 7 buy, 2 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$40.10 mean target +100.4% upside Strong Buy (3.00)
$25.00 Low $55.00 High
MetricValue
Current Price$20.01
Target Low$25.00
Target Mean$40.10
Target Median$39.50
Target High$55.00
# Analysts10
RecommendationStrong Buy (3.00)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-0.71 $-0.82 $-0.55 51.8% +4.1% 2↑ 0↓ $0.0B 35.8% 5
Next Q
2026-09-30
$-0.72 $-0.79 $-0.64 31.7% +6.4% 2↑ 0↓ $0.0B -22.6% 5
Current FY
2026-12-31
$-2.90 $-3.17 $-2.60 37.0% +5.2% 2↑ 0↓ $0.0B -67.5% 5
Next FY
2027-12-31
$-2.95 $-3.70 $-2.22 -1.8% +8.6% 2↑ 0↓ $0.0B 205.0% 5

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-0.710
7d ago$-0.740+0.030
30d ago$-0.740+0.030
60d ago$-0.767+0.057
90d ago$-0.720+0.010
9 analyst firms have rated this stock: 0 upgrades, 1 downgrades, 3 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
May 19, 2026 Chardan Capital MAINTAIN Buy Buy
May 15, 2026 Wells Fargo MAINTAIN Overweight Overweight
May 15, 2026 Guggenheim MAINTAIN Buy Buy
May 15, 2026 HC Wainwright & Co. DOWNGRADE Buy Neutral
Mar 30, 2026 Oppenheimer MAINTAIN Outperform Outperform
Mar 30, 2026 Chardan Capital MAINTAIN Buy Buy
Mar 30, 2026 HC Wainwright & Co. MAINTAIN Buy Buy
Mar 20, 2026 Morgan Stanley MAINTAIN Overweight Overweight
Mar 20, 2026 Chardan Capital MAINTAIN Buy Buy
Mar 11, 2026 Raymond James INITIATE Strong Buy
Feb 25, 2026 Stifel INITIATE Buy
Jan 21, 2026 Chardan Capital INITIATE Buy
Jan 9, 2026 HC Wainwright & Co. REITERATE Buy Buy
Jan 7, 2026 Leerink Partners MAINTAIN Outperform Outperform
Jan 7, 2026 Morgan Stanley MAINTAIN Overweight Overweight
Jan 7, 2026 Guggenheim MAINTAIN Buy Buy
Jan 6, 2026 Wells Fargo MAINTAIN Overweight Overweight
Dec 18, 2025 HC Wainwright & Co. MAINTAIN Buy Buy

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 20268720088%
May 1, 20268810094%
Apr 1, 20268810094%
Mar 1, 20267710093%
Feb 1, 20266710093%
Jan 1, 20266710093%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

50°
Neutral
Bearish Neutral Bullish
2 mentions 0 bullish 0 bearish 2 time periods

Reddit Sentiment History

DateMentionsSentimentBullishBearishThreads
Mar 30, 2026156° Neutral001
Mar 30, 2026156° Neutral001

Recent Reddit Threads

r/investing Neutral 2mo ago
Market Close Report - Monday, March 30, 2026
▲ 1 💬 0 ⚡ 0.5
Jun 9, 2026
short_volume
Short Volume: ALMS — 84.7% short (0.7M / 0.9M)
Short: 728,623 | Exempt: 5,000 | TRF Vol: 860,164 | Short Ratio: 84.7% | Off-exchange volume (dark pool + OTC)
Jun 8, 2026
short_volume
Short Volume: ALMS — 68.8% short (0.7M / 1.1M)
Short: 731,043 | Exempt: 216 | TRF Vol: 1,062,705 | Short Ratio: 68.8% | Off-exchange volume (dark pool + OTC)
May 20, 2026
earnings_calendar
ALMS Q1 2026 Earnings Scheduled — 2026-05-20
May 19, 2026
short_volume
Short Volume: ALMS — 65.3% short (0.4M / 0.6M)
Short: 388,675 | Exempt: 8,839 | TRF Vol: 595,098 | Short Ratio: 65.3% | Off-exchange volume (dark pool + OTC)
May 18, 2026
short_volume
Short Volume: ALMS — 61.0% short (0.3M / 0.6M)
Short: 349,178 | Exempt: 31,371 | TRF Vol: 572,824 | Short Ratio: 61.0% | Off-exchange volume (dark pool + OTC)
May 14, 2026
earnings
Alumis Reports First Quarter 2026 Financial Results and Highlights Recent Achievements
<p align="center"><em>– Late</em>-<em>breaking oral presentation of Phase 3 envudeucitinib data in moderate</em>-<em>to</em>-<em>severe plaque psorias
May 13, 2026
earnings_calendar
ALMS Q1 2026 Earnings Scheduled — 2026-05-13
May 12, 2026
earnings_calendar
ALMS Q1 2026 Earnings Scheduled — 2026-05-12
Apr 27, 2026
Clinical Trial
Phase 2 Placebo-Controlled Study to Assess the Safety and Efficacy of ESK-001 in Active Systemic Lupus Erythematosus
Phase Phase 2 — ACTIVE_NOT_RECRUITING
Apr 27, 2026
clinical_trial_readout
T-90d Trial Readout: Envudeucitinib (Phase 2)
Trial: Phase 2 Placebo-Controlled Study to Assess the Safety and Efficacy of ESK-001 in Active Systemic Lupus Erythematosus Sponsor: Alumis Inc Phase:
Apr 24, 2026
short_volume
Short Volume: ALMS — 55.6% short (0.3M / 0.6M)
Short: 334,594 | Exempt: 0 | TRF Vol: 601,991 | Short Ratio: 55.6% | Off-exchange volume (dark pool + OTC)
Apr 23, 2026
short_volume
Short Volume: ALMS — 67.1% short (0.6M / 0.9M)
Short: 585,279 | Exempt: 25,156 | TRF Vol: 872,155 | Short Ratio: 67.1% | Off-exchange volume (dark pool + OTC)
Apr 21, 2026
short_volume
Short Volume: ALMS — 59.8% short (0.4M / 0.7M)
Short: 431,289 | Exempt: 18,624 | TRF Vol: 721,134 | Short Ratio: 59.8% | Off-exchange volume (dark pool + OTC)
Apr 20, 2026
clinical_trial_readout
T-90d Trial Readout: Envudeucitinib (Phase 2)
Trial: Phase 2 Placebo-Controlled Study to Assess the Safety and Efficacy of ESK-001 in Active Systemic Lupus Erythematosus Sponsor: Alumis Inc Phase:
Apr 16, 2026
short_volume
Short Volume: ALMS — 63.6% short (0.4M / 0.7M)
Short: 424,540 | Exempt: 31,913 | TRF Vol: 667,512 | Short Ratio: 63.6% | Off-exchange volume (dark pool + OTC)
Apr 14, 2026
short_volume
Short Volume: ALMS — 55.3% short (0.3M / 0.6M)
Short: 321,441 | Exempt: 0 | TRF Vol: 581,364 | Short Ratio: 55.3% | Off-exchange volume (dark pool + OTC)
Apr 13, 2026
Clinical Trial
A Study in Patients With Moderate to Severe Plaque Psoriasis to Evaluate the Efficacy and Safety of ESK-001
Phase Phase 3 — COMPLETED
Apr 13, 2026
Clinical Trial
A Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Moderate to Severe Plaque Psoriasis
Phase Phase 3 — COMPLETED