SLN

Silence Therapeutics plc

OTC · Pharmaceutical Preparations · Inc. X0 · CIK 0001479615
$6.69 +0.15% $313.1M
3 New Institutional Positions
Vol
Market Cap$313.1M
Cap SizeSmall Cap
Inst. Holders23 funds
Inst. Value$12.8M
Inst. Activity3 buys / 2 sells
Insider Activity2B / 2S
SEC Reports1
Exchange OTC·Sector Pharmaceutical Preparations·Inc. X0·CIK 0001479615·Prev Close $6.68

Recent Activity

Jun 3, 2026 clinical_trial_readout
T-90d Trial Readout: SLN124 (Phase 2)
Trial: Study to Assess SLN124 in Patients With Polycythemia Vera Sponsor: Silence Therapeutics plc P
Mar 5, 2026 SEC
Silence Therapeutics reported a significant year-over-year decline in revenue and increased net loss, driven by the conc
8-K — Impact 6/10
Oct 27, 2025 Insider
Griffiths Richard Ian sold 2,000 shares
10%+ Owner
Oct 27, 2025 Insider
Griffiths Richard Ian bought 2,000 shares
10%+ Owner
Aug 3, 2025 Insider
Griffiths Richard Ian bought 20,000 shares
10%+ Owner
Inst.
BlackRock, Inc. — DOUBLED
204,777 shares ($1.1M)
Inst.
BANK OF MONTREAL /CAN/ — ADD
202,901 shares ($1.1M)

Price Targets

Historical data — last covering-analyst action Mar 2026. No current recommendation available.
$31.20 (Mar 2026)
Current $6.69 Low $4.00 Median $25.00 High $75.00 5 analysts
$4.00 $75.00

Analyst Ratings

Historical Analyst Actions
DateFirmActionRating
Mar 13, 2026 HC Wainwright & Co. REITERATE Buy → Buy

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-0.11 ▼ -10.0% $-0.11 — $-0.11 80% YoY 1
Next Q $-0.10 $-0.10 — $-0.10 33% YoY 1
Current FY $-0.40 ▼ -2.6% $-0.40 — $-0.40 78% YoY 1
Next FY $-0.39 $-0.39 — $-0.39 3% YoY 1

Top Institutional Holders

FundValueMove
ROYAL BANK OF CANADATRIM
CITADEL ADVISORS LLC$6.5MDOUBLED
BlackRock, Inc.$1.1MDOUBLED
BANK OF MONTREAL /CAN/$1.1MADD
MARSHALL WACE, LLP$893.9KADD

Recent Insider Trades

DateInsiderTypeValue
Oct 27, 2025Griffiths RichardSELL$0.00
Oct 27, 2025Griffiths RichardBUY$0.00
Aug 3, 2025Griffiths RichardBUY$0.00
Aug 3, 2025Griffiths RichardSELL$0.00
23 institutional holders with $12.8M total value (2,445,012 shares) as of 2026-Q1. Top holders: ROYAL, CITADEL, BlackRock,. Net buying activity: 3 institutions added/increased vs 2 reduced.

Top Institutional Holders — 2026-Q1

#FundSharesValue% of TrackedLast Move
1ROYAL BANK OF CANADA16$0.000.0%TRIM -42.2%
2CITADEL ADVISORS LLC1,234,807$6.5M50.8%DOUBLED +274.0%
3BlackRock, Inc.204,777$1.1M8.4%DOUBLED +179.9%
4BANK OF MONTREAL /CAN/202,901$1.1M8.3%ADD +26.4%
5MARSHALL WACE, LLP169,616$893.9K7.0%ADD +87.1%
6HSBC HOLDINGS PLC122,834$640.0K5.0%TRIM -28.9%
7Point72 Asset Management, L.P.119,711$630.9K4.9%NEAR_EXIT -97.5%
8SUSQUEHANNA INTERNATIONAL GROUP, LLP115,281$607.5K4.7%
9MORGAN STANLEY65,486$345.1K2.7%NEAR_EXIT -79.8%
10GOLDMAN SACHS GROUP INC52,511$276.7K2.2%
11BANK OF AMERICA CORP /DE/29,773$156.9K1.2%DOUBLED +903.8%
12RAYMOND JAMES FINANCIAL INC25,000$131.8K1.0%
13SUSQUEHANNA INTERNATIONAL GROUP, LLP20,200$106.5K0.8%
14SUSQUEHANNA INTERNATIONAL GROUP, LLP18,900$99.6K0.8%
15TWO SIGMA INVESTMENTS, LP16,203$85.4K0.7%TRIM -37.8%
16RHUMBLINE ADVISERS13,935$73.4K0.6%DOUBLED +121.6%
17CITADEL ADVISORS LLC11,300$59.6K0.5%DOUBLED +274.0%
18BARCLAYS PLC2,937$15.5K0.1%ADD +83.8%
19Mirae Asset Global Investments Co., Ltd.2,450$12.9K0.1%ADD +25.7%
20JONES FINANCIAL COMPANIES LLLP2,500$12.3K0.1%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
BlackRock, Inc.DOUBLED73,153204,777+179.9%$1.1M2026-Q1
BANK OF MONTREAL /CAN/ADD160,474202,901+26.4%$1.1M2026-Q1
HSBC HOLDINGS PLCTRIM172,834122,834-28.9%$640.0K2026-Q1
MORGAN STANLEYNEAR_EXIT324,63065,486-79.8%$345.1K2026-Q1
BANK OF AMERICA CORP /DE/DOUBLED2,96629,773+903.8%$156.9K2026-Q1
MORGAN STANLEYTRIM1,207,724324,630-73.1%$2.0M2025-Q4
MARSHALL WACE, LLPADD83,219155,680+87.1%$946.5K2025-Q4
TWO SIGMA INVESTMENTS, LPTRIM63,24739,344-37.8%$239.2K2025-Q4
RHUMBLINE ADVISERSDOUBLED5,86512,999+121.6%$79.0K2025-Q4
Mirae Asset Global Investments Co., Ltd.ADD1,8162,282+25.7%$13.9K2025-Q4
UBS Group AGADD228,509307,363+34.5%$1.6M2025-Q3
MARSHALL WACE, LLPTRIM175,86283,219-52.7%$431.9K2025-Q3
BlackRock, Inc.TRIM168,23561,832-63.2%$320.9K2025-Q3
BANK OF AMERICA CORP /DE/TRIM5,0953,531-30.7%$18.3K2025-Q3
UBS Group AGTRIM319,514228,509-28.5%$1.3M2025-Q2
Woodline Partners LPTRIM134,49262,459-53.6%$362.3K2025-Q2
RHUMBLINE ADVISERSDOUBLED1,8756,196+230.5%$35.9K2025-Q2
ROYAL BANK OF CANADATRIM4,2632,462-42.2%$14.0K2025-Q2
MARSHALL WACE, LLPTRIM488,889228,418-53.3%$644.1K2025-Q1
BANK OF MONTREAL /CAN/DOUBLED65,007158,593+144.0%$447.2K2025-Q1
Walleye Capital LLCDOUBLED36,397136,150+274.1%$383.9K2025-Q1
Woodline Partners LPTRIM498,732134,492-73.0%$379.3K2025-Q1
TWO SIGMA INVESTMENTS, LPTRIM142,05276,008-46.5%$214.3K2025-Q1
BANK OF AMERICA CORP /DE/NEAR_EXIT499,06664,886-87.0%$183.0K2025-Q1
Point72 Asset Management, L.P.NEAR_EXIT633,10016,032-97.5%$45.2K2025-Q1
1 unique insiders with 4 transactions. Net insider value: $0.00 ($0.00 bought, $0.00 sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
Oct 27, 2025Griffiths Richard Ian10%+ OwnerSELL2,000
Oct 27, 2025Griffiths Richard Ian10%+ OwnerBUY2,000
Aug 3, 2025Griffiths Richard Ian10%+ OwnerBUY20,000
Aug 3, 2025Griffiths Richard Ian10%+ OwnerSELL20,000
1 SEC filing reports analyzed. Sentiment: 0 bullish, 0 bearish, 1 mixed, 0 neutral. Avg impact: 6.0/10.

No press releases analyzed yet. Press releases are collected from GlobeNewsWire and analyzed by the LLM pipeline.

Analyst Price Targets

Historical data — last covering-analyst action Mar 2026. No current recommendation available.
$31.20 mean target (Mar 2026)
$4.00 Low $75.00 High
MetricValue
Current Price$6.69
Target Low$4.00
Target Mean$31.20
Target Median$25.00
Target High$75.00
# Analysts5
Recommendation— (no recent coverage)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-0.11 $-0.11 $-0.11 80.0% -10.0% 0↑ 1↓ $0.0B 523.2% 1
Next Q
2026-09-30
$-0.10 $-0.10 $-0.10 33.3% +0.0% 1↑ 0↓ $0.0B 737.8% 1
Current FY
2026-12-31
$-0.40 $-0.40 $-0.40 78.4% -2.6% 0↑ 1↓ $0.0B 582.9% 1
Next FY
2027-12-31
$-0.39 $-0.39 $-0.39 2.5% +0.0% 1↑ 0↓ $0.0B 44.3% 1

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-0.110
7d ago$-0.100-0.010
30d ago$-0.100-0.010
60d ago$-0.100-0.010
90d ago$-0.460+0.350
1 analyst firms have rated this stock: 0 upgrades, 0 downgrades, 0 initiations.

Historical Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
Mar 13, 2026 HC Wainwright & Co. REITERATE Buy Buy

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

No Reddit sentiment data available yet. Sentiment is analyzed from Reddit investment communities on a rolling basis.

Jun 3, 2026
Clinical Trial
Study to Assess SLN124 in Patients With Polycythemia Vera
Phase Phase 2 — ACTIVE_NOT_RECRUITING
Jun 3, 2026
clinical_trial_readout
T-90d Trial Readout: SLN124 (Phase 2)
Trial: Study to Assess SLN124 in Patients With Polycythemia Vera Sponsor: Silence Therapeutics plc Phase: Phase 2 | Status: ACTIVE_NOT_RECRUITING Cond
Apr 24, 2026
short_interest
FTD: SLN — 78,743 shares ($0.6M) failed to deliver
Settlement: 20260424, Price: $7.84, FTD Value: $617,345.12, SILENCE THERAPEUTICS PLC SPONS