QTTB

Q32 Bio Inc.

Nasdaq · Pharmaceutical Preparations · Inc. DE · CIK 0001661998
$12.64 -0.47% $214.3M
Insider Buying Cluster (2 insiders)High Impact Filing (8/10)3 New Institutional Positions
Vol
Market Cap$214.3M
Cap SizeMicro Cap
Analyst ConsensusStrong Buy (82%)
Inst. Holders25 funds
Inst. Value$13.9M
Inst. Activity3 buys / 1 sells
Insider Activity2B / 3S
Insider Net $$19.9M
SEC Reports6
Exchange Nasdaq·Sector Pharmaceutical Preparations·Inc. DE·CIK 0001661998·Prev Close $12.70

Recent Activity

Jun 4, 2026 short_volume
Short Volume: QTTB — 69.8% short (0.5M / 0.7M)
Short: 486,236 | Exempt: 0 | TRF Vol: 696,739 | Short Ratio: 69.8% | Off-exchange volume (dark pool
Jun 2, 2026 SEC
Directors OrbiMed Advisors and Xu Diyong each purchased $10M of QTTB common stock at $8/share on May 28, 2026, for a tot
CLUSTER — Impact 8/10
May 28, 2026 Insider
ORBIMED ADVISORS LLC bought 1,250,000 shares
Director @ $8.00 ($10.0M)
May 28, 2026 Insider
Xu Diyong bought 1,250,000 shares
Director @ $8.00 ($10.0M)
May 5, 2026 SEC
Q32 Bio reported Q1 2026 net loss of $7.6M ($0.54/share), narrower than the $11.0M loss in Q1 2025, driven by lower R&D
8-K — Impact 4/10
Apr 24, 2026 SEC
Q32 Bio Inc. has filed an additional prospectus supplement to raise up to $75 million through its at-the-market (ATM) of
8-K — Impact 6/10
Feb 25, 2026 Insider
Morrison Jodie Pope sold 9,896 shares
CEO @ $4.51 ($44.7K)
Inst.
BlackRock, Inc. — ADD
86,147 shares ($553.1K)

Price Targets

$14.25 +12.7% upside Buy
Current $12.64 Low $10.00 Median $13.50 High $20.00 4 analysts
$10.00 $20.00

Analyst Ratings

Strong Buy82% buy · 11 analysts
3Strong Buy
6Buy
2Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
May 22, 2026 Mizuho INITIATE Outperform
May 18, 2026 Cantor Fitzgerald INITIATE Overweight
May 5, 2026 HC Wainwright & Co. REITERATE Buy → Buy
Feb 25, 2026 HC Wainwright & Co. INITIATE Buy

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-0.56 ▼ -46.8% $-0.66 — $-0.48 28% YoY 5
Next Q $-0.41 ▼ -4.1% $-0.50 — $-0.20 32% YoY 5
Current FY $-1.82 ▲ +13.1% $-2.20 — $-1.24 -175% YoY 5
Next FY $-2.23 ▲ +34.2% $-2.80 — $-1.69 -23% YoY 5

Top Institutional Holders

FundValueMove
Carlyle Group Inc.$7.1M
VANGUARD CAPITAL MANAGEMENT LLC$2.0M
MACKENZIE FINANCIAL CORP$1.6M
RENAISSANCE TECHNOLOGIES LLC$1.3MDOUBLED
BlackRock, Inc.$553.1KADD

Recent Insider Trades

DateInsiderTypeValue
May 28, 2026ORBIMED ADVISORSBUY$10.0M
May 28, 2026Xu DiyongBUY$10.0M
Feb 25, 2026Morrison JodieSELL$44.7K
Feb 25, 2026Violette SheliaSELL$12.7K
Feb 25, 2026Kalowski LeeSELL$18.0K
25 institutional holders with $13.9M total value (2,172,240 shares) as of 2026-Q1. Top holders: Carlyle, VANGUARD, MACKENZIE. Net buying activity: 3 institutions added/increased vs 1 reduced.

Top Institutional Holders — 2026-Q1

#FundSharesValue% of TrackedLast Move
1Carlyle Group Inc.1,102,741$7.1M50.8%
2VANGUARD CAPITAL MANAGEMENT LLC306,401$2.0M14.1%
3MACKENZIE FINANCIAL CORP246,304$1.6M11.3%
4RENAISSANCE TECHNOLOGIES LLC206,915$1.3M9.5%DOUBLED +110.6%
5BlackRock, Inc.86,147$553.1K4.0%ADD +43.7%
6MARSHALL WACE, LLP52,440$336.7K2.4%
7VANGUARD FIDUCIARY TRUST CO49,995$321.0K2.3%
8TWO SIGMA INVESTMENTS, LP42,346$271.9K1.9%ADD +48.6%
9STATE STREET CORP41,514$266.5K1.9%ADD +95.5%
10CITADEL ADVISORS LLC15,481$99.4K0.7%
11MORGAN STANLEY9,560$61.4K0.4%ADD +74.5%
12FMR LLC3,400$21.8K0.2%NEAR_EXIT -78.8%
13ROYAL BANK OF CANADA2,744$18.0K0.1%DOUBLED +274.3%
14FEDERATED HERMES, INC.2,273$14.6K0.1%DOUBLED +443.1%
15Vanguard Global Advisers, LLC1,915$12.3K0.1%
16Rockefeller Capital Management L.P.577$3.7K0.0%
17JONES FINANCIAL COMPANIES LLLP500$3.6K0.0%
18Russell Investments Group, Ltd.454$2.9K0.0%TRIM -30.3%
19NISA INVESTMENT ADVISORS, LLC166$1.1K0.0%TRIM -71.8%
20NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO111$713.000.0%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
BlackRock, Inc.ADD59,93286,147+43.7%$553.1K2026-Q1
STATE STREET CORPADD21,23741,514+95.5%$266.5K2026-Q1
MORGAN STANLEYADD5,4789,560+74.5%$61.4K2026-Q1
CWM, LLCTRIM5439-27.8%$250.002026-Q1
CWM, LLCNEAR_EXIT21954-75.3%2025-Q4
RENAISSANCE TECHNOLOGIES LLCDOUBLED47,30099,600+110.6%$330.7K2025-Q4
BlackRock, Inc.TRIM93,00559,932-35.6%$199.0K2025-Q4
TWO SIGMA INVESTMENTS, LPADD31,50646,825+48.6%$155.5K2025-Q4
MORGAN STANLEYTRIM11,3435,478-51.7%$18.2K2025-Q4
FMR LLCNEAR_EXIT15,8673,364-78.8%$11.2K2025-Q4
BANK OF AMERICA CORP /DE/TRIM1,5251,035-32.1%$3.4K2025-Q4
Allworth Financial LPNEAR_EXIT61098-83.9%$326.002025-Q4
HRT FINANCIAL LPADD14,83624,698+66.5%$81.002025-Q4
CWM, LLCNEAR_EXIT4,769219-95.4%2025-Q3
BlackRock, Inc.TRIM178,67793,005-47.9%$184.2K2025-Q3
RENAISSANCE TECHNOLOGIES LLCTRIM77,00047,300-38.6%$93.7K2025-Q3
FMR LLCTRIM42,43915,867-62.6%$31.4K2025-Q3
MORGAN STANLEYTRIM18,64811,343-39.2%$22.5K2025-Q3
UBS Group AGTRIM12,5765,246-58.3%$10.4K2025-Q3
BANK OF AMERICA CORP /DE/TRIM2,1981,525-30.6%$3.0K2025-Q3
Allworth Financial LPDOUBLED16610+3712.5%$1.2K2025-Q3
NISA INVESTMENT ADVISORS, LLCTRIM589166-71.8%$329.002025-Q3
STATE STREET CORPNEAR_EXIT137,49826,937-80.4%$40.1K2025-Q2
UBS Group AGTRIM33,43112,576-62.4%$18.7K2025-Q2
Mariner, LLCNEAR_EXIT84,78011,780-86.1%$17.6K2025-Q2
8 unique insiders with 11 transactions. Net insider value: $19.9M ($20.0M bought, $75.4K sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
May 28, 2026ORBIMED ADVISORS LLCDirectorBUY1,250,000$8.00$10.0M
May 28, 2026Xu DiyongDirectorBUY1,250,000$8.00$10.0M
Feb 25, 2026Morrison Jodie PopeCEOSELL9,896$4.51$44.7K
Feb 25, 2026Violette Shelia M.Chief Scientific OfficerSELL2,815$4.51$12.7K
Feb 25, 2026Kalowski LeeCFO and PresidentSELL3,995$4.51$18.0K
Feb 24, 2026Violette Shelia M.Chief Scientific OfficerAWARD37,500
Feb 24, 2026Kalowski LeeCFO and PresidentAWARD53,250
Feb 24, 2026Morrison Jodie PopeCEOAWARD132,000
Jan 15, 2026Lundberg Sven AnteDirectorAWARD20,363$2.75$56.0K
Jan 15, 2026LAPORTE KATHLEENDirectorAWARD23,272$2.75$64.0K
Jan 15, 2026GRAYZEL DAVID S.DirectorAWARD16,363$2.75$45.0K

No press releases analyzed yet. Press releases are collected from GlobeNewsWire and analyzed by the LLM pipeline.

Current analyst consensus: Strong Buy (82% buy). Based on 11 analysts: 3 strong buy, 6 buy, 2 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$14.25 mean target +12.7% upside Buy (3.00)
$10.00 Low $20.00 High
MetricValue
Current Price$12.64
Target Low$10.00
Target Mean$14.25
Target Median$13.50
Target High$20.00
# Analysts4
RecommendationBuy (3.00)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-0.56 $-0.66 $-0.48 28.5% -46.8% $0.0B 0.0% 5
Next Q
2026-09-30
$-0.41 $-0.50 $-0.20 32.3% -4.1% $0.0B 0.0% 5
Current FY
2026-12-31
$-1.82 $-2.20 $-1.24 -175.0% +13.1% 1↑ 0↓ $0.0B -98.1% 5
Next FY
2027-12-31
$-2.23 $-2.80 $-1.69 -22.8% +34.2% 2↑ 0↓ $0.0B 0.0% 5

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-0.558
7d ago$-0.583+0.025
30d ago$-0.380-0.178
60d ago$-0.380-0.178
90d ago$0.000-0.558
3 analyst firms have rated this stock: 0 upgrades, 0 downgrades, 3 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
May 22, 2026 Mizuho INITIATE Outperform
May 18, 2026 Cantor Fitzgerald INITIATE Overweight
May 5, 2026 HC Wainwright & Co. REITERATE Buy Buy
Feb 25, 2026 HC Wainwright & Co. INITIATE Buy

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 20263620082%
May 1, 20263420078%
Apr 1, 20263420078%
Mar 1, 20263420078%
Feb 1, 20263320075%
Jan 1, 20263320075%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

No Reddit sentiment data available yet. Sentiment is analyzed from Reddit investment communities on a rolling basis.

Jun 4, 2026
short_volume
Short Volume: QTTB — 69.8% short (0.5M / 0.7M)
Short: 486,236 | Exempt: 0 | TRF Vol: 696,739 | Short Ratio: 69.8% | Off-exchange volume (dark pool + OTC)
Jun 1, 2026
short_volume
Short Volume: QTTB — 61.0% short (0.3M / 0.5M)
Short: 332,756 | Exempt: 0 | TRF Vol: 545,804 | Short Ratio: 61.0% | Off-exchange volume (dark pool + OTC)
May 29, 2026
short_volume
Short Volume: QTTB — 57.2% short (0.3M / 0.5M)
Short: 308,123 | Exempt: 7,261 | TRF Vol: 538,539 | Short Ratio: 57.2% | Off-exchange volume (dark pool + OTC)
May 7, 2026
earnings_calendar
QTTB Q1 2026 Earnings Scheduled — 2026-05-07
Apr 2, 2026
Clinical Trial
A Phase 2a Proof-of-Concept Trial of Bempikibart (ADX-914) for the Treatment of Severe Alopecia Areata (SIGNAL-AA)
Phase Phase 2 — ACTIVE_NOT_RECRUITING
Apr 2, 2026
clinical_trial_readout
T-60d Trial Readout: bempikibart (ADX-914) (Phase 2)
Trial: A Phase 2a Proof-of-Concept Trial of Bempikibart (ADX-914) for the Treatment of Severe Alopecia Areata (SIGNAL-AA) Sponsor: Q32 Bio Inc. Phase:
Apr 1, 2026
clinical_trial_readout
T-90d Trial Readout: bempikibart (ADX-914) (Phase 2)
Trial: A Phase 2a Proof-of-Concept Trial of Bempikibart (ADX-914) for the Treatment of Severe Alopecia Areata (SIGNAL-AA) Sponsor: Q32 Bio Inc. Phase:
Mar 17, 2026
earnings_calendar
QTTB Q4 2025 Earnings After Market Close — 2026-03-17