PLRX

PLIANT THERAPEUTICS, INC.

Nasdaq · Pharmaceutical Preparations · Inc. DE · CIK 0001746473
$1.15 0.00% $71.2M
High Impact Filing (7/10)
Vol
Market Cap$71.2M
Cap SizeMicro Cap
Analyst ConsensusSell (9%)
Inst. Holders7 funds
Inst. Value$7.4M
Inst. Activity0 buys / 2 sells
Reddit Sentiment60° Warm
SEC Reports6
Exchange Nasdaq·Sector Pharmaceutical Preparations·Inc. DE·CIK 0001746473·Prev Close $1.15

Recent Activity

May 11, 2026 SEC
Pliant Therapeutics reported Q1 2026 EPS of -$0.38, missing consensus of -$0.36 by 6.2%. Revenue was $0 (pre-revenue bio
PRESS-RELEASE — Impact 6/10
May 11, 2026 SEC
Pliant Therapeutics reported Q1 2026 results with a net loss of $20.0M ($0.32/share), narrower than the $56.2M loss in Q
8-K — Impact 4/10
Apr 17, 2026 SEC
Pliant Therapeutics announced the retirement of three board members effective at the 2026 Annual Meeting and a broad sto
8-K — Impact 6/10
Apr 17, 2026 Insider
Cummings Keith Lamont sold 76,047 shares
Chief Financial Officer @ $0.00 ($0.00)
Apr 17, 2026 Insider
Cheung Lily sold 123,000 shares
Chief Human Resource Officer @ $0.00 ($0.00)
Apr 17, 2026 Insider
Cummings Keith Lamont sold 76,047 shares
Chief Financial Officer @ $0.00 ($0.00)
Inst.
MORGAN STANLEY — NEAR_EXIT
548,962 shares ($669.7K)
Inst.
FMR LLC — TRIM
1,934 shares ($2.4K)

Price Targets

$2.67 +124.1% upside Strong Buy
Current $1.19 Low $2.00 Median $3.00 High $3.00 3 analysts
$2.00 $3.00

Analyst Ratings

Strong Sell9% buy · 11 analysts
0Strong Buy
1Buy
6Hold
2Sell
2Strong Sell
Recent Analyst Actions
DateFirmActionRating
Mar 13, 2026 Canaccord Genuity MAINTAIN Hold → Hold
Mar 12, 2026 Piper Sandler MAINTAIN Overweight → Overweight

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-0.35 ▲ +7.3% $-0.37 — $-0.32 51% YoY 5
Next Q $-0.37 ▲ +2.6% $-0.42 — $-0.32 14% YoY 5
Current FY $-1.42 ▲ +7.2% $-1.56 — $-1.29 41% YoY 5
Next FY $-0.95 ▲ +37.3% $-1.53 — $0.49 33% YoY 5

Top Institutional Holders

FundValueMove
VANGUARD GROUP INC$3.4M
RENAISSANCE TECHNOLOGIES LLC$1.3MDOUBLED
TWO SIGMA INVESTMENTS, LP$1.2MDOUBLED
BANK OF AMERICA CORP$868.4KADD
MORGAN STANLEY$669.7KNEAR_EXIT

Recent Insider Trades

DateInsiderTypeValue
Apr 17, 2026Cummings KeithD$0.00
Apr 17, 2026Cheung LilyD$0.00
Apr 17, 2026Cummings KeithA$0.00
Apr 17, 2026Cheung LilyA$0.00
Apr 17, 2026Kuo MinnieA$0.00

Reddit Sentiment

60°
Warm
Bearish Neutral Bullish
1 mentions 1 bullish 0 bearish
7 institutional holders with $7.4M total value (6,080,075 shares) as of 2025-Q4. Top holders: VANGUARD, RENAISSANCE, TWO. Net selling activity: 2 institutions trimmed/exited vs 0 added.

Top Institutional Holders — 2025-Q4

#FundSharesValue% of TrackedLast Move
1VANGUARD GROUP INC2,818,241$3.4M46.4%
2RENAISSANCE TECHNOLOGIES LLC1,045,818$1.3M17.2%DOUBLED +406.0%
3TWO SIGMA INVESTMENTS, LP953,293$1.2M15.7%DOUBLED +181.6%
4BANK OF AMERICA CORP /DE/711,777$868.4K11.7%ADD +47.3%
5MORGAN STANLEY548,962$669.7K9.0%NEAR_EXIT -84.3%
6FMR LLC1,934$2.4K0.0%TRIM -61.1%
7WELLS FARGO & COMPANY/MN50$61.000.0%NEAR_EXIT -97.9%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
MORGAN STANLEYNEAR_EXIT3,507,288548,962-84.3%$669.7K2025-Q4
FMR LLCTRIM4,9741,934-61.1%$2.4K2025-Q4
UBS Group AGTRIM2,646,5561,322,017-50.0%$2.0M2025-Q3
RENAISSANCE TECHNOLOGIES LLCDOUBLED199,9481,011,802+406.0%$1.5M2025-Q3
TWO SIGMA INVESTMENTS, LPDOUBLED278,158783,255+181.6%$1.2M2025-Q3
BANK OF AMERICA CORP /DE/ADD480,530708,056+47.3%$1.0M2025-Q3
WELLS FARGO & COMPANY/MNNEAR_EXIT2,32950-97.9%$74.002025-Q3
CHARLES SCHWAB INVESTMENT MANAGEMENT INCEXIT251,3650-100.0%$0.002025-Q3
BANK OF AMERICA CORP /DE/TRIM920,736480,530-47.8%$557.4K2025-Q2
CHARLES SCHWAB INVESTMENT MANAGEMENT INCTRIM389,349251,365-35.4%$291.6K2025-Q2
RENAISSANCE TECHNOLOGIES LLCADD152,500199,948+31.1%$231.9K2025-Q2
FMR LLCTRIM22,2106,507-70.7%$7.5K2025-Q2
WELLS FARGO & COMPANY/MNNEAR_EXIT35,4512,329-93.4%$2.7K2025-Q2
MORGAN STANLEYDOUBLED782,0043,051,514+290.2%$4.1M2025-Q1
UBS Group AGDOUBLED628,2812,645,546+321.1%$3.6M2025-Q1
TWO SIGMA INVESTMENTS, LPDOUBLED97,078275,287+183.6%$371.6K2025-Q1
RENAISSANCE TECHNOLOGIES LLCDOUBLED27,800152,500+448.6%$205.9K2025-Q1
CITADEL ADVISORS LLCNEAR_EXIT494,48945,165-90.9%$61.0K2025-Q1
WELLS FARGO & COMPANY/MNTRIM85,88035,451-58.7%$47.9K2025-Q1
FMR LLCNEAR_EXIT3,876,59822,210-99.4%$30.0K2025-Q1
UBS Group AGDOUBLED230,308628,281+172.8%$8.3M2024-Q4
CITADEL ADVISORS LLCDOUBLED112,954494,489+337.8%$6.5M2024-Q4
RENAISSANCE TECHNOLOGIES LLCTRIM101,20027,800-72.5%$366.1K2024-Q4
CHARLES SCHWAB INVESTMENT MANAGEMENT INCNEW456,663$5.1M2024-Q3
4 unique insiders with 0 transactions. Net insider value: $0.00 ($0.00 bought, $0.00 sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
Apr 17, 2026Cummings Keith LamontChief Financial OfficerD76,047$0.00$0.00
Apr 17, 2026Cheung LilyChief Human Resource OfficerD123,000$0.00$0.00
Apr 17, 2026Cummings Keith LamontChief Financial OfficerA76,047$0.00$0.00
Apr 17, 2026Cheung LilyChief Human Resource OfficerA123,000$0.00$0.00
Apr 17, 2026Kuo MinnieChief Operating OfficerA150,000$0.00$0.00
Apr 17, 2026Coulie BernardPresident and CEOD146,841$0.00$0.00
Apr 17, 2026Coulie BernardPresident and CEOA146,841$0.00$0.00
Apr 17, 2026Kuo MinnieChief Operating OfficerD150,000$0.00$0.00

No press releases analyzed yet. Press releases are collected from GlobeNewsWire and analyzed by the LLM pipeline.

Current analyst consensus: Strong Sell (9% buy). Based on 11 analysts: 0 strong buy, 1 buy, 6 hold, 2 sell, 2 strong sell.

Analyst Price Targets

$2.67 mean target +124.1% upside Strong Buy (3.00)
$2.00 Low $3.00 High
MetricValue
Current Price$1.19
Target Low$2.00
Target Mean$2.67
Target Median$3.00
Target High$3.00
# Analysts3
RecommendationStrong Buy (3.00)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-0.35 $-0.37 $-0.32 51.3% +7.3% 3↑ 0↓ $0.0B 0.0% 5
Next Q
2026-09-30
$-0.37 $-0.42 $-0.32 14.1% +2.6% 2↑ 0↓ $0.0B 0.0% 5
Current FY
2026-12-31
$-1.42 $-1.56 $-1.29 40.8% +7.2% 4↑ 0↓ $0.0B 0.0% 5
Next FY
2027-12-31
$-0.95 $-1.53 $0.49 33.1% +37.3% 5↑ 0↓ $0.0B 0.0% 5

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-0.346
7d ago$-0.350+0.004
30d ago$-0.373+0.027
60d ago$-0.373+0.027
90d ago$-0.453+0.108
2 analyst firms have rated this stock: 0 upgrades, 0 downgrades, 0 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
Mar 13, 2026 Canaccord Genuity MAINTAIN Hold Hold
Mar 12, 2026 Piper Sandler MAINTAIN Overweight Overweight

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 2026016229%
May 1, 2026016229%
Apr 1, 2026016229%
Mar 1, 2026017228%
Feb 1, 2026017228%
Jan 1, 2026017228%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

60°
Warm
Bearish Neutral Bullish
1 mentions 1 bullish 0 bearish 1 time period

Reddit Sentiment History

DateMentionsSentimentBullishBearishThreads
Feb 7, 2026160° Warm101

Recent Reddit Threads

r/pennystocks Bullish 4mo ago
Pliant Therapeutics - Institutional holdings
▲ 4 💬 2 ⚡ 0.0
May 21, 2026
routine
Pliant Therapeutics Announces Upcoming Presentation at the 2026 American Society of Clinical Oncology Annual Meeting
<p align="center"><em>Highlights FORTIFY, the Phase 1b indication expansion trial of PLN-101095 </em><br><em>enrolling patients with ICI-refractory so
May 11, 2026
earnings
Pliant Therapeutics Provides Corporate Update and Reports First Quarter 2026 Financial Results
<p align="center"><em>First participant dosed in FORTIFY, a Phase 1b indication expansion trial of PLN-101095</em><br><br><em>Oral presentation at AAC
May 11, 2026
earnings_calendar
PLRX Q1 2026 Earnings Scheduled — 2026-05-11
May 6, 2026
other
Pliant Therapeutics to Participate in the RBC Capital Markets Global Healthcare Conference
<p>SOUTH SAN FRANCISCO, Calif., May 06, 2026 (GLOBE NEWSWIRE) -- Pliant Therapeutics, Inc. (Nasdaq: PLRX), a clinical-stage biotechnology company fo
May 6, 2026
earnings_calendar
PLRX Q1 2026 Earnings Scheduled — 2026-05-06
Apr 30, 2026
other
Pliant Therapeutics Announces First Patient Dosed in FORTIFY, the Phase 1b Indication Expansion Trial Evaluating PLN-101095 in Patients with ICI-Refractory Solid Tumors
<p align="left">SOUTH SAN FRANCISCO, Calif., April 30, 2026 (GLOBE NEWSWIRE) -- Pliant Therapeutics (Nasdaq: PLRX) today announced the dosing of the
Apr 18, 2026
routine
Pliant Therapeutics Announces Presentation of Updated Data from the Phase 1 Trial of PLN-101095 in Patients with ICI-Refractory Solid Tumors at the 2026 AACR Annual Meeting
<p align="center"><em>Confirmed responses deepened with an average maximum tumor reduction from baseline of 89% and median time on treatment increased
Mar 11, 2026
earnings
Pliant Therapeutics Provides Corporate Update and Reports Fourth Quarter 2025 Financial Results
<p align="center"><em>PLN-101095 Phase 1 data showed deep and durable ongoing responses in checkpoint inhibitor refractory solid tumors</em></p>
Mar 3, 2026
earnings_calendar
PLRX Q4 2025 Earnings After Market Close — 2026-03-03
Mar 2, 2026
earnings_calendar
PLRX Q4 2025 Earnings After Market Close — 2026-03-02