MDGL

MADRIGAL PHARMACEUTICALS, INC.

Nasdaq · Pharmaceutical Preparations · Inc. DE · CIK 0001157601
$501.19 +0.29% $11.6B
Insider Selling Cluster (2 insiders)High Impact Filing (7/10)24 New Institutional Positions23 Institutional Exits
Vol
Market Cap$11.6B
Cap SizeLarge Cap
Analyst ConsensusStrong Buy (87%)
Inst. Holders50 funds
Inst. Value$10.4B
Inst. Activity24 buys / 23 sells
Insider Activity0B / 9S
Insider Net $-$3.0M
SEC Reports6
Press Releases1
Exchange Nasdaq·Sector Pharmaceutical Preparations·Inc. DE·CIK 0001157601·Prev Close $499.76

Recent Activity

Jun 4, 2026 other
Madrigal Pharmaceuticals Announces Grants of Inducement Awards under Nasdaq Listing Rule 5635(c)(4)
<p>CONSHOHOCKEN, Pa., June 04, 2026 (GLOBE NEWSWIRE) -- Madrigal Pharmaceuticals, Inc. (NASDAQ: MD
Jun 1, 2026 Insider
Soergel David sold 1,042 shares
Chief Medical Officer @ $495.74 ($516.6K)
May 22, 2026 SEC
Two Madrigal insiders (Director Levy and CMO Soergel) sold a combined $456K in open-market transactions, representing ap
CLUSTER — Impact 3/10
May 22, 2026 Insider
Levy Richard S sold 40 shares
Director @ $506.68 ($20.3K)
May 18, 2026 Insider
Soergel David sold 844 shares
Chief Medical Officer @ $515.90 ($435.4K)
May 6, 2026 SEC
Madrigal Pharmaceuticals reported Q1 2026 Rezdiffra net sales of $311.3M (+127% YoY), beating consensus revenue estimate
8-K — Impact 7/10
Apr 28, 2026 SEC
Madrigal Pharmaceuticals reclassified two directors (Julian Baker and Daniel Brennan) to Class I to balance board classe
8-K — Impact 2/10
Inst.
JANUS HENDERSON GROUP PLC — ADD
2,018,647 shares ($1.1B)

Price Targets

$678.71 +35.4% upside Strong Buy
Current $501.19 Low $542.00 Median $649.50 High $964.00 14 analysts
$542.00 $964.00

Analyst Ratings

Strong Buy87% buy · 23 analysts
5Strong Buy
15Buy
3Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
Jun 11, 2026 B of A Securities MAINTAIN Neutral → Neutral
May 13, 2026 Truist Securities MAINTAIN Buy → Buy
May 7, 2026 Canaccord Genuity MAINTAIN Buy → Buy
May 7, 2026 Evercore ISI Group MAINTAIN Outperform → Outperform
May 6, 2026 HC Wainwright & Co. REITERATE Buy → Buy

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-2.23 ▼ -58.4% $-2.38 — $-2.03 -17% YoY 3
Next Q $-1.03 ▼ -69.4% $-1.42 — $-0.82 79% YoY 3
Current FY $-6.52 ▼ -12.8% $-7.11 — $-6.15 49% YoY 3
Next FY $12.38 ▼ -3.2% $10.01 — $16.78 290% YoY 3

Top Institutional Holders

FundValueMove
NOMURA ASSET MANAGEMENT CO
BAKER BROS. ADVISORS LP$1.1B
JANUS HENDERSON GROUP PLC$1.1BADD
RTW INVESTMENTS, LP$1.0B
Avoro Capital Advisors LLC$951.8M

Recent Insider Trades

DateInsiderTypeValue
Jun 1, 2026Soergel DavidSELL$516.6K
May 22, 2026Levy RichardSELL$20.3K
May 18, 2026Soergel DavidSELL$435.4K
Mar 6, 2026Sibold WilliamSELL$718.3K
Mar 6, 2026Kelley ShannonSELL$155.5K
50 institutional holders with $10.4B total value (19,788,900 shares) as of 2026-Q1. Top holders: NOMURA, BAKER, JANUS. Net buying activity: 24 institutions added/increased vs 23 reduced.

Top Institutional Holders — 2026-Q1

#FundSharesValue% of TrackedLast Move
1NOMURA ASSET MANAGEMENT CO LTD$0.000.0%
2BAKER BROS. ADVISORS LP2,141,701$1.1B10.8%
3JANUS HENDERSON GROUP PLC2,018,647$1.1B10.2%ADD +27.4%
4RTW INVESTMENTS, LP1,993,687$1.0B10.1%
5Avoro Capital Advisors LLC1,818,181$951.8M9.2%
6BlackRock, Inc.1,559,965$816.6M7.9%
7PAULSON & CO. INC.1,392,188$728.8M7.0%
8VANGUARD PORTFOLIO MANAGEMENT LLC841,145$440.3M4.3%
9VANGUARD CAPITAL MANAGEMENT LLC827,144$433.0M4.2%
10WELLINGTON MANAGEMENT GROUP LLP694,958$363.8M3.5%ADD +50.6%
11STATE STREET CORP609,525$319.1M3.1%
12FMR LLC511,728$267.9M2.6%
13CITADEL ADVISORS LLC453,843$237.6M2.3%
14WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC340,519$178.3M1.7%
15Invesco Ltd.329,519$172.5M1.7%
16Polar Capital Holdings Plc289,310$151.4M1.5%
17GOLDMAN SACHS GROUP INC277,371$145.2M1.4%
18Hood River Capital Management LLC249,511$130.6M1.3%
19Point72 Asset Management, L.P.225,510$118.0M1.1%ADD +78.4%
20CHARLES SCHWAB INVESTMENT MANAGEMENT INC216,720$113.4M1.1%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
JANUS HENDERSON GROUP PLCADD1,584,8432,018,647+27.4%$1.1B2026-Q1
WELLINGTON MANAGEMENT GROUP LLPADD461,402694,958+50.6%$363.8M2026-Q1
Point72 Asset Management, L.P.ADD126,435225,510+78.4%$118.0M2026-Q1
MORGAN STANLEYADD150,462191,294+27.1%$100.1M2026-Q1
BANK OF AMERICA CORP /DE/TRIM416,025189,527-54.4%$99.2M2026-Q1
ADAGE CAPITAL PARTNERS GP, L.L.C.DOUBLED23,226185,331+697.9%$97.0M2026-Q1
TORONTO DOMINION BANKNEW130,460$68.3M2026-Q1
AMERIPRISE FINANCIAL INCDOUBLED29,28798,181+235.2%$51.4M2026-Q1
DEUTSCHE BANK AG\TRIM192,10998,067-49.0%$51.3M2026-Q1
ALKEON CAPITAL MANAGEMENT LLCTRIM240,00080,000-66.7%$41.9M2026-Q1
Nuveen, LLCTRIM118,36362,060-47.6%$32.5M2026-Q1
SCHRODER INVESTMENT MANAGEMENT GROUPADD29,05139,852+37.2%$20.1M2026-Q1
Rockefeller Capital Management L.P.ADD19,66133,849+72.2%$17.7M2026-Q1
BNP Paribas Asset Management Holding S.A.DOUBLED15,34732,879+114.2%$17.2M2026-Q1
Connor, Clark & Lunn Investment Management Ltd.TRIM58,29527,937-52.1%$14.6M2026-Q1
Clearbridge Investments, LLCNEW24,447$12.8M2026-Q1
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEMTRIM31,28623,198-25.9%$12.1M2026-Q1
WCM INVESTMENT MANAGEMENT, LLCADD17,25423,560+36.5%$11.9M2026-Q1
MARSHALL WACE, LLPTRIM39,57821,902-44.7%$11.5M2026-Q1
Assenagon Asset Management S.A.DOUBLED5,39016,033+197.5%$8.4M2026-Q1
HighTower Advisors, LLCDOUBLED1,17313,914+1086.2%$7.3M2026-Q1
STATE OF WISCONSIN INVESTMENT BOARDADD9,27613,432+44.8%$7.0M2026-Q1
Neuberger Berman Group LLCTRIM18,66012,849-31.1%$6.7M2026-Q1
CANADA PENSION PLAN INVESTMENT BOARDTRIM46,12012,260-73.4%$6.4M2026-Q1
TUDOR INVESTMENT CORP ET ALDOUBLED5,28511,630+120.1%$6.1M2026-Q1
7 unique insiders with 20 transactions. Net insider value: -$3.0M ($0.00 bought, $3.0M sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
Jun 1, 2026Soergel DavidChief Medical OfficerSELL1,042$495.74$516.6K
May 22, 2026Levy Richard SDirectorSELL40$506.68$20.3K
May 18, 2026Soergel DavidChief Medical OfficerSELL844$515.90$435.4K
Mar 6, 2026Sibold William JohnPresident and CEOSELL1,663$431.94$718.3K
Mar 6, 2026Kelley Shannon TGeneral CounselSELL360$431.94$155.5K
Mar 6, 2026Dier MardiEVP and CFOSELL646$431.94$279.0K
Mar 6, 2026Huntsman CaroleChief Commercial OfficerSELL419$431.94$181.0K
Mar 6, 2026Taub RebeccaDirectorSELL491$431.94$212.1K
Mar 4, 2026Dier MardiEVP and CFOAWARD6,519
Mar 4, 2026Sibold William JohnPresident and CEOAWARD18,743
Mar 4, 2026Huntsman CaroleChief Commercial OfficerAWARD3,989
Mar 4, 2026Huntsman CaroleChief Commercial OfficerAWARD4,986
Mar 4, 2026Dier MardiEVP and CFOAWARD5,215
Mar 4, 2026Sibold William JohnPresident and CEOAWARD14,995
Mar 4, 2026Kelley Shannon TGeneral CounselAWARD4,017
Mar 4, 2026Kelley Shannon TGeneral CounselAWARD5,022
Mar 4, 2026Soergel DavidChief Medical OfficerAWARD4,374
Mar 4, 2026Soergel DavidChief Medical OfficerAWARD5,467
Mar 2, 2026Dier MardiEVP and CFOSELL1,183$427.21$505.4K
Feb 23, 2026Levy Richard SDirectorEXERCISE2,500$7.36$18.4K
Current analyst consensus: Strong Buy (87% buy). Based on 23 analysts: 5 strong buy, 15 buy, 3 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$678.71 mean target +35.4% upside Strong Buy (1.38)
$542.00 Low $964.00 High
MetricValue
Current Price$501.19
Target Low$542.00
Target Mean$678.71
Target Median$649.50
Target High$964.00
# Analysts14
RecommendationStrong Buy (1.38)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-2.23 $-2.38 $-2.03 -17.4% -58.4% 0↑ 1↓ $0.3B 64.3% 3
Next Q
2026-09-30
$-1.03 $-1.42 $-0.82 79.2% -69.4% $0.4B 36.3% 3
Current FY
2026-12-31
$-6.52 $-7.11 $-6.15 48.7% -12.8% 1↑ 2↓ $1.5B 56.0% 3
Next FY
2027-12-31
$12.38 $10.01 $16.78 289.8% -3.2% 2↑ 1↓ $2.2B 47.5% 3

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-2.230
7d ago$-2.230
30d ago$-1.408-0.822
60d ago$-1.408-0.822
90d ago$-1.438-0.792
8 analyst firms have rated this stock: 0 upgrades, 0 downgrades, 1 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
Jun 11, 2026 B of A Securities MAINTAIN Neutral Neutral
May 13, 2026 Truist Securities MAINTAIN Buy Buy
May 7, 2026 Canaccord Genuity MAINTAIN Buy Buy
May 7, 2026 Evercore ISI Group MAINTAIN Outperform Outperform
May 6, 2026 HC Wainwright & Co. REITERATE Buy Buy
Feb 20, 2026 B of A Securities MAINTAIN Neutral Neutral
Jan 28, 2026 Barclays INITIATE Overweight
Jan 20, 2026 Citizens MAINTAIN Market Outperform Market Outperform
Dec 19, 2025 Piper Sandler MAINTAIN Overweight Overweight

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 202651530087%
May 1, 202651530087%
Apr 1, 202651530087%
Mar 1, 202651530087%
Feb 1, 202651630088%
Jan 1, 202661520091%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

No Reddit sentiment data available yet. Sentiment is analyzed from Reddit investment communities on a rolling basis.

Jun 4, 2026
other
Madrigal Pharmaceuticals Announces Grants of Inducement Awards under Nasdaq Listing Rule 5635(c)(4)
<p>CONSHOHOCKEN, Pa., June 04, 2026 (GLOBE NEWSWIRE) -- Madrigal Pharmaceuticals, Inc. (NASDAQ: MDGL), a biopharmaceutical company focused on delive
Jun 4, 2026
Clinical Trial
Study of MGL-3196 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)
Phase Phase 2 — COMPLETED
May 6, 2026
earnings
Madrigal Pharmaceuticals Reports First-Quarter 2026 Financial Results and Provides Corporate Updates
<p>CONSHOHOCKEN, Pa., May 06, 2026 (GLOBE NEWSWIRE) -- Madrigal Pharmaceuticals, Inc. (Nasdaq: MDGL), a biopharmaceutical company focused on deliver
May 6, 2026
earnings_calendar
MDGL Q1 2026 Earnings Before Market Open — 2026-05-06
Apr 22, 2026
earnings
Madrigal Pharmaceuticals to Release First-Quarter 2026 Financial Results and Host Webcast on May 6, 2026
<p>CONSHOHOCKEN, Pa., April 22, 2026 (GLOBE NEWSWIRE) -- Madrigal Pharmaceuticals, Inc. (Nasdaq: MDGL) announced today that it will release its firs
Apr 21, 2026
other
Madrigal Pharmaceuticals Announces Grants of Inducement Awards under Nasdaq Listing Rule 5635(c)(4)
<p>CONSHOHOCKEN, Pa., April 21, 2026 (GLOBE NEWSWIRE) -- Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL), a biopharmaceutical company focused on delive
Apr 7, 2026
other
Madrigal Pharmaceuticals Announces Grants of Inducement Awards under Nasdaq Listing Rule 5635(c)(4)
<p>CONSHOHOCKEN, Pa., April 07, 2026 (GLOBE NEWSWIRE) -- Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL), a biopharmaceutical company focused on delive
Apr 7, 2026
short_interest
FTD: MDGL — 4,628 shares ($2.5M) failed to deliver
Settlement: 20260407, Price: $533.88, FTD Value: $2,470,796.64, MADRIGAL PHARMACEUTICALS INC C
Mar 26, 2026
short_volume
Short Volume: MDGL — 60.5% short (0.3M / 0.5M)
Short: 319,168 | Exempt: 1,293 | TRF Vol: 527,766 | Short Ratio: 60.5% | Off-exchange volume (dark pool + OTC)
Mar 19, 2026
activist
Madrigal Pharmaceuticals Announces Grants of Inducement Awards under Nasdaq Listing Rule 5635(c)(4)
<p align="left">CONSHOHOCKEN, Pa., March 19, 2026 (GLOBE NEWSWIRE) -- Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL), a biopharmaceutical company focu
Mar 5, 2026
other
Madrigal Pharmaceuticals Announces Grants of Inducement Awards under Nasdaq Listing Rule 5635(c)(4)
<p>CONSHOHOCKEN, Pa., March 05, 2026 (GLOBE NEWSWIRE) -- Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL), a biopharmaceutical company focused on delive
Feb 20, 2026
short_interest
FTD: MDGL — 2,898 shares ($1.3M) failed to deliver
Settlement: 20260220, Price: $436.87, FTD Value: $1,266,049.26, MADRIGAL PHARMACEUTICALS INC C
Feb 2, 2026
short_interest
FTD: MDGL — 1,133 shares ($0.6M) failed to deliver
Settlement: 20260202, Price: $489.31, FTD Value: $554,388.23, MADRIGAL PHARMACEUTICALS INC C