KRYS

Krystal Biotech, Inc.

Nasdaq · Biological Products, (No Diagnostic Substances) · CIK 0001711279
$301.00 -2.21% $8.9B
Insider Selling Cluster (3 insiders)4 New Institutional Positions
Vol
Market Cap$8.9B
Cap SizeMid Cap
Analyst ConsensusStrong Buy (89%)
Inst. Holders8 funds
Inst. Value$2.0B
Inst. Activity4 buys / 0 sells
Insider Activity0B / 11S
Insider Net $-$7.7M
SEC Reports8
Exchange Nasdaq·Sector Biological Products, (No Diagnostic Substances)·CIK 0001711279·Prev Close $307.79

Recent Activity

Jun 5, 2026 SEC
President and CEO Krishnan Krish S and President of R&D Krishnan Suma each sold 320 shares of Krystal Biotech on June 4,
CLUSTER — Impact 2/10
Jun 4, 2026 Insider
Krishnan Suma sold 320 shares
President, R&D @ $300.75 ($96.2K)
Jun 4, 2026 Insider
Krishnan Krish S sold 320 shares
President and CEO @ $300.75 ($96.2K)
May 26, 2026 Insider
Thomas John Charles sold 642 shares
EVP, General Counsel @ $302.03 ($193.9K)
May 16, 2026 SEC
Citigroup upgrades KRYS to Buy — PT $309 (+56% from prior); stock at $312.58, near consensus mean
ANALYST-UPGRADE — Impact 5/10
Apr 16, 2026 SEC
Citigroup upgrades KRYS to Buy — PT $309 (+18%)
ANALYST-UPGRADE — Impact 4/10
Inst.
NORGES BANK — NEW
284,573 shares ($70.2M)
Inst.
BANK OF AMERICA CORP — ADD
190,807 shares ($47.0M)

Price Targets

$322.78 +7.2% upside Buy
Current $301.00 Low $241.00 Median $310.00 High $399.00 9 analysts
$241.00 $399.00

Analyst Ratings

Strong Buy89% buy · 18 analysts
7Strong Buy
9Buy
2Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
Jun 1, 2026 HC Wainwright & Co. REITERATE Buy → Buy
May 22, 2026 HC Wainwright & Co. REITERATE Buy → Buy
May 18, 2026 HC Wainwright & Co. REITERATE Buy → Buy
May 5, 2026 Citigroup MAINTAIN Buy → Buy
May 5, 2026 Evercore ISI Group MAINTAIN Outperform → Outperform

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $1.94 ▲ +15.2% $1.28 — $3.64 51% YoY 9
Next Q $2.19 ▲ +10.3% $1.42 — $4.12 -18% YoY 9
Current FY $8.38 ▲ +10.6% $6.21 — $14.52 22% YoY 10
Next FY $10.08 ▼ -1.1% $6.66 — $13.42 20% YoY 10

Top Institutional Holders

FundValueMove
FMR LLC$1.1B
VANGUARD GROUP INC$685.1M
NORGES BANK$70.2MNEW
CHARLES SCHWAB INVESTMENT MANAGEMENT$59.9MNEW
MORGAN STANLEY$54.6M

Recent Insider Trades

DateInsiderTypeValue
Jun 4, 2026Krishnan SumaSELL$96.2K
Jun 4, 2026Krishnan KrishSELL$96.2K
May 26, 2026Thomas JohnSELL$193.9K
Mar 4, 2026Krishnan KrishSELL$124.3K
Mar 4, 2026Krishnan SumaSELL$104.7K
8 institutional holders with $2.0B total value (8,102,980 shares) as of 2025-Q4. Top holders: FMR, VANGUARD, NORGES. Net buying activity: 4 institutions added/increased vs 0 reduced.

Top Institutional Holders — 2025-Q4

#FundSharesValue% of TrackedLast Move
1FMR LLC4,349,628$1.1B53.7%
2VANGUARD GROUP INC2,778,845$685.1M34.3%
3NORGES BANK284,573$70.2M3.5%NEW
4CHARLES SCHWAB INVESTMENT MANAGEMENT INC242,774$59.9M3.0%NEW
5MORGAN STANLEY221,481$54.6M2.7%
6BANK OF AMERICA CORP /DE/190,807$47.0M2.4%ADD +38.3%
7WELLS FARGO & COMPANY/MN31,572$7.8M0.4%ADD +60.6%
8RENAISSANCE TECHNOLOGIES LLC3,300$813.6K0.0%NEW

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
NORGES BANKNEW284,573$70.2M2025-Q4
BANK OF AMERICA CORP /DE/ADD137,995190,807+38.3%$47.0M2025-Q4
WELLS FARGO & COMPANY/MNADD19,65331,572+60.6%$7.8M2025-Q4
RENAISSANCE TECHNOLOGIES LLCNEW3,300$813.6K2025-Q4
UBS Group AGADD149,440278,673+86.5%$49.2M2025-Q3
NORGES BANKEXIT282,7060-100.0%$0.002025-Q3
RENAISSANCE TECHNOLOGIES LLCEXIT89,8000-100.0%$0.002025-Q3
NORGES BANKNEW282,706$38.9M2025-Q2
UBS Group AGADD81,119149,440+84.2%$20.5M2025-Q2
BANK OF AMERICA CORP /DE/ADD92,561121,812+31.6%$16.7M2025-Q2
RENAISSANCE TECHNOLOGIES LLCDOUBLED11,20089,800+701.8%$12.3M2025-Q2
CITADEL ADVISORS LLCTRIM48,01512,596-73.8%$2.3M2025-Q1
NORGES BANKEXIT219,5280-100.0%$0.002025-Q1
UBS Group AGDOUBLED36,329100,131+175.6%$15.7M2024-Q4
CHARLES SCHWAB INVESTMENT MANAGEMENT INCNEW240,216$43.7M2024-Q3
6 unique insiders with 11 transactions. Net insider value: -$7.7M ($0.00 bought, $7.7M sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
Jun 4, 2026Krishnan SumaPresident, R&DSELL320$300.75$96.2K
Jun 4, 2026Krishnan Krish SPresident and CEOSELL320$300.75$96.2K
May 26, 2026Thomas John CharlesEVP, General CounselSELL642$302.03$193.9K
Mar 4, 2026Krishnan Krish SPresident and CEOSELL483$257.31$124.3K
Mar 4, 2026Krishnan SumaPresident, R&DSELL407$257.32$104.7K
Mar 2, 2026ROMANO KATHRYNChief Accounting OfficerSELL750$267.60$200.7K
Feb 27, 2026JANNEY DANIELDirectorSELL9,430$275.45$2.6M
Feb 27, 2026Krishnan SumaPresident, R&DM22,500$0.00$0.00
Feb 27, 2026Krishnan SumaPresident, R&DM22,500$0.00$0.00
Feb 27, 2026Krishnan SumaPresident, R&DM4,000$0.00$0.00
Feb 27, 2026Krishnan SumaPresident, R&DA18,100$0.00$0.00
Feb 27, 2026Krishnan SumaPresident, R&DA7,256$0.00$0.00
Feb 27, 2026Krishnan SumaPresident, R&DA43,536$0.00$0.00
Feb 27, 2026Krishnan Krish SPresident and CEOM8,750$0.00$0.00
Feb 27, 2026Krishnan Krish SPresident and CEOM8,750$0.00$0.00
Feb 27, 2026Krishnan Krish SPresident and CEOM26,250$0.00$0.00
Feb 27, 2026Krishnan Krish SPresident and CEOA45,249$0.00$0.00
Feb 27, 2026Krishnan Krish SPresident and CEOA18,140$0.00$0.00
Feb 27, 2026ROMANO KATHRYNChief Accounting OfficerM7,500$0.00$0.00
Feb 27, 2026ROMANO KATHRYNChief Accounting OfficerM7,500$0.00$0.00
Feb 27, 2026ROMANO KATHRYNChief Accounting OfficerM550$0.00$0.00
Feb 27, 2026ROMANO KATHRYNChief Accounting OfficerA13,575$0.00$0.00
Feb 27, 2026ROMANO KATHRYNChief Accounting OfficerA5,442$0.00$0.00
Feb 26, 2026JANNEY DANIELDirectorSELL5,103$275.28$1.4M
Feb 25, 2026JANNEY DANIELDirectorSELL700$275.00$192.5K
Feb 24, 2026JANNEY DANIELDirectorM37,895$2.46$93.2K
Feb 24, 2026JANNEY DANIELDirectorM37,895$0.00$0.00
Feb 19, 2026ROSSI DINO ADirectorM18,950$8.79$166.6K
Feb 19, 2026ROSSI DINO ADirectorSELL8,116$260.49$2.1M
Feb 19, 2026ROSSI DINO ADirectorM18,950$0.00$0.00
Feb 9, 2026ROMANO KATHRYNChief Accounting OfficerM12,500$0.00$0.00
Feb 9, 2026ROMANO KATHRYNChief Accounting OfficerG750$0.00$0.00
Feb 9, 2026ROMANO KATHRYNChief Accounting OfficerSELL2,000$270.56$541.1K
Feb 9, 2026ROMANO KATHRYNChief Accounting OfficerM12,500$63.55$794.4K

No press releases analyzed yet. Press releases are collected from GlobeNewsWire and analyzed by the LLM pipeline.

Current analyst consensus: Strong Buy (89% buy). Based on 18 analysts: 7 strong buy, 9 buy, 2 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$322.78 mean target +7.2% upside Buy (1.18)
$241.00 Low $399.00 High
MetricValue
Current Price$301.00
Target Low$241.00
Target Mean$322.78
Target Median$310.00
Target High$399.00
# Analysts9
RecommendationBuy (1.18)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$1.94 $1.28 $3.64 50.5% +15.2% 1↑ 2↓ $0.1B 30.4% 9
Next Q
2026-09-30
$2.19 $1.42 $4.12 -17.8% +10.3% 1↑ 3↓ $0.1B 40.4% 9
Current FY
2026-12-31
$8.38 $6.21 $14.52 22.5% +10.6% 3↑ 2↓ $0.5B 35.9% 10
Next FY
2027-12-31
$10.08 $6.66 $13.42 20.3% -1.1% 4↑ 2↓ $0.7B 28.1% 10

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$1.942
7d ago$1.942
30d ago$1.685+0.257
60d ago$1.747+0.195
90d ago$1.705+0.237
10 analyst firms have rated this stock: 1 upgrades, 0 downgrades, 1 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
Jun 1, 2026 HC Wainwright & Co. REITERATE Buy Buy
May 22, 2026 HC Wainwright & Co. REITERATE Buy Buy
May 18, 2026 HC Wainwright & Co. REITERATE Buy Buy
May 5, 2026 Citigroup MAINTAIN Buy Buy
May 5, 2026 Evercore ISI Group MAINTAIN Outperform Outperform
May 4, 2026 HC Wainwright & Co. REITERATE Buy Buy
Mar 27, 2026 Wolfe Research INITIATE Peer Perform
Feb 25, 2026 Guggenheim MAINTAIN Buy Buy
Feb 18, 2026 Citigroup MAINTAIN Buy Buy
Feb 18, 2026 Chardan Capital MAINTAIN Buy Buy
Feb 17, 2026 Jefferies MAINTAIN Buy Buy
Feb 2, 2026 Goldman Sachs MAINTAIN Buy Buy
Jan 22, 2026 B of A Securities MAINTAIN Buy Buy
Jan 12, 2026 Citigroup MAINTAIN Buy Buy
Jan 9, 2026 TD Cowen MAINTAIN Buy Buy
Jan 9, 2026 Citigroup MAINTAIN Buy Buy
Jan 9, 2026 HC Wainwright & Co. REITERATE Buy Buy
Jan 6, 2026 Citigroup UPGRADE Neutral Buy

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 20267920089%
May 1, 20267920089%
Apr 1, 20267920089%
Mar 1, 20267910094%
Feb 1, 202671010094%
Jan 1, 202661020089%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

No Reddit sentiment data available yet. Sentiment is analyzed from Reddit investment communities on a rolling basis.

May 4, 2026
earnings
Krystal Biotech Announces First Quarter 2026 Financial and Operating Results
<p align="center">$116.4 million in 1Q VYJUVEK global revenue and $846.7 million since launch</p>
May 4, 2026
earnings_calendar
KRYS Q1 2026 Earnings Before Market Open — 2026-05-04
Apr 30, 2026
other
Krystal Biotech to Present at Upcoming Scientific Conferences
<p>PITTSBURGH, April 30, 2026 (GLOBE NEWSWIRE) -- <a href="https://www.krystalbio.com/" rel="nofollow" target="_blank" title=""><u>Krystal Biotech,
Apr 21, 2026
earnings
Krystal Biotech to Report First Quarter 2026 Financial Results on May 4, 2026
<p>PITTSBURGH, April 21, 2026 (GLOBE NEWSWIRE) -- <a href="https://www.krystalbio.com/" rel="nofollow" target="_blank" title=""><u>Krystal Biotech,
Apr 21, 2026
short_interest
FTD: KRYS — 6,493 shares ($1.8M) failed to deliver
Settlement: 20260421, Price: $276.50, FTD Value: $1,795,314.5, KRYSTAL BIOTECH INC COM (USA)
Mar 9, 2026
short_interest
FTD: KRYS — 2,097 shares ($0.5M) failed to deliver
Settlement: 20260309, Price: $253.69, FTD Value: $531,987.93, KRYSTAL BIOTECH INC COM (USA)
Feb 19, 2026
short_interest
FTD: KRYS — 24,545 shares ($7.0M) failed to deliver
Settlement: 20260219, Price: $283.29, FTD Value: $6,953,353.05, KRYSTAL BIOTECH INC COM (USA)
Feb 9, 2026
short_interest
FTD: KRYS — 2,032 shares ($0.6M) failed to deliver
Settlement: 20260209, Price: $272.74, FTD Value: $554,207.68, KRYSTAL BIOTECH INC COM (USA)