IOVA

IOVANCE BIOTHERAPEUTICS, INC.

Nasdaq · Biological Products, (No Diagnostic Substances) · Inc. DE · CIK 0001425205
$4.00 -5.44% $1.7B
5 New Institutional Positions
Vol
Market Cap$1.7B
Cap SizeSmall Cap
Analyst ConsensusStrong Buy (81%)
Inst. Holders8 funds
Inst. Value$165.2M
Inst. Activity5 buys / 1 sells
Reddit Sentiment70° Bullish
SEC Reports2
Press Releases2
Exchange Nasdaq·Sector Biological Products, (No Diagnostic Substances)·Inc. DE·CIK 0001425205·Prev Close $4.23

Recent Activity

Jun 5, 2026 Insider
Vogt Frederick G sold 15,625 shares
Interim CEO & General Counsel @ $0.00 ($0.00)
Jun 5, 2026 Insider
GRAF FINCKENSTEIN FRIEDRICH sold 7,813 shares
Chief Medical Officer @ $0.00 ($0.00)
Jun 5, 2026 Insider
GRAF FINCKENSTEIN FRIEDRICH sold 3,976 shares
Chief Medical Officer @ $4.23 ($16.8K)
Jun 3, 2026 other
Iovance’s Amtagvi® (lifileucel) Granted Approval for the Treatment of Advanced Melanoma in Australia
<p align="center"><em>First T cell therapy for a solid tumor cancer and first treatment option appro
May 22, 2026 Press
Iovance Biotherapeutics granted inducement stock options covering 93,340 shares to 13 new non-executive employees under
Impact 2/10
Apr 28, 2026 SEC
Iovance Biotherapeutics filed additional definitive proxy materials for its 2026 Annual Meeting, with proposals includin
DEFA14A — Impact 3/10
Apr 27, 2026 SEC
Iovance Biotherapeutics issued a press release announcing an upcoming earnings call for Q1 2026 financial results, but d
PRESS-RELEASE — Impact 3/10
Inst.
BANK OF AMERICA CORP — DOUBLED
14,277,813 shares ($39.0M)

Price Targets

$8.80 +126.8% upside Strong Buy
Current $3.88 Low $4.00 Median $9.50 High $14.00 10 analysts
$4.00 $14.00

Analyst Ratings

Strong Buy81% buy · 16 analysts
3Strong Buy
10Buy
3Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
May 8, 2026 Chardan Capital MAINTAIN Buy → Buy
Apr 10, 2026 Chardan Capital MAINTAIN Buy → Buy
Mar 5, 2026 UBS MAINTAIN Neutral → Neutral
Mar 3, 2026 Citizens UPGRADE Market Perform → Market Outperform
Feb 25, 2026 Barclays MAINTAIN Overweight → Overweight

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-0.13 ▲ +4.4% $-0.16 — $-0.11 59% YoY 8
Next Q $-0.12 ▲ +1.1% $-0.17 — $-0.09 50% YoY 8
Current FY $-0.56 ▼ -4.3% $-0.72 — $-0.46 48% YoY 8
Next FY $-0.32 ▼ -14.7% $-0.46 — $-0.23 43% YoY 7

Top Institutional Holders

FundValueMove
VANGUARD GROUP INC$74.3M
BANK OF AMERICA CORP$39.0MDOUBLED
MORGAN STANLEY$25.1MADD
TWO SIGMA INVESTMENTS, LP$12.0MADD
CHARLES SCHWAB INVESTMENT MANAGEMENT$7.5MADD

Recent Insider Trades

DateInsiderTypeValue
Jun 5, 2026Vogt FrederickM$0.00
Jun 5, 2026GRAF FINCKENSTEINM$0.00
Jun 5, 2026GRAF FINCKENSTEINF$16.8K
Jun 5, 2026GRAF FINCKENSTEINM$0.00
Jun 5, 2026Puri RajF$16.3K

Reddit Sentiment

70°
Bullish
Bearish Neutral Bullish
18 mentions 11 bullish 2 bearish
8 institutional holders with $165.2M total value (60,503,474 shares) as of 2025-Q4. Top holders: VANGUARD, BANK, MORGAN. Net buying activity: 5 institutions added/increased vs 1 reduced.

Top Institutional Holders — 2025-Q4

#FundSharesValue% of TrackedLast Move
1VANGUARD GROUP INC27,207,079$74.3M45.0%
2BANK OF AMERICA CORP /DE/14,277,813$39.0M23.6%DOUBLED +127.4%
3MORGAN STANLEY9,191,840$25.1M15.2%ADD +64.7%
4TWO SIGMA INVESTMENTS, LP4,397,989$12.0M7.3%ADD +60.5%
5CHARLES SCHWAB INVESTMENT MANAGEMENT INC2,753,343$7.5M4.6%ADD +30.7%
6WELLS FARGO & COMPANY/MN1,993,337$5.4M3.3%ADD +31.4%
7RENAISSANCE TECHNOLOGIES LLC651,000$1.8M1.1%NEW
8FMR LLC31,073$84.8K0.1%TRIM -28.7%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
BANK OF AMERICA CORP /DE/DOUBLED6,279,23014,277,813+127.4%$39.0M2025-Q4
MORGAN STANLEYADD5,581,5639,191,840+64.7%$25.1M2025-Q4
TWO SIGMA INVESTMENTS, LPADD2,740,8544,397,989+60.5%$12.0M2025-Q4
WELLS FARGO & COMPANY/MNADD1,517,3641,993,337+31.4%$5.4M2025-Q4
RENAISSANCE TECHNOLOGIES LLCNEW651,000$1.8M2025-Q4
FMR LLCTRIM43,58131,073-28.7%$84.8K2025-Q4
BANK OF AMERICA CORP /DE/ADD4,029,5686,279,230+55.8%$13.6M2025-Q3
TWO SIGMA INVESTMENTS, LPTRIM4,633,4512,740,854-40.8%$5.9M2025-Q3
CHARLES SCHWAB INVESTMENT MANAGEMENT INCADD1,916,4862,504,542+30.7%$5.4M2025-Q3
WELLS FARGO & COMPANY/MNADD1,074,2501,517,364+41.2%$3.3M2025-Q3
UBS Group AGTRIM1,779,412936,504-47.4%$2.0M2025-Q3
FMR LLCADD33,77943,581+29.0%$94.6K2025-Q3
RENAISSANCE TECHNOLOGIES LLCEXIT4,887,2000-100.0%$0.002025-Q3
MORGAN STANLEYADD4,018,3746,450,933+60.5%$11.1M2025-Q2
RENAISSANCE TECHNOLOGIES LLCADD3,511,4004,887,200+39.2%$8.4M2025-Q2
TWO SIGMA INVESTMENTS, LPDOUBLED396,9944,633,451+1067.1%$8.0M2025-Q2
BANK OF AMERICA CORP /DE/ADD3,017,1854,029,568+33.6%$6.9M2025-Q2
UBS Group AGTRIM2,496,7491,779,412-28.7%$3.1M2025-Q2
WELLS FARGO & COMPANY/MNADD858,5701,074,250+25.1%$1.8M2025-Q2
FMR LLCTRIM82,82633,779-59.2%$58.1K2025-Q2
RENAISSANCE TECHNOLOGIES LLCNEW3,511,400$11.7M2025-Q1
WELLS FARGO & COMPANY/MNADD580,245858,570+48.0%$2.9M2025-Q1
TWO SIGMA INVESTMENTS, LPNEW396,994$1.3M2025-Q1
FMR LLCTRIM117,43982,826-29.5%$275.8K2025-Q1
NORGES BANKEXIT416,2370-100.0%$0.002025-Q1
6 unique insiders with 0 transactions. Net insider value: $0.00 ($0.00 bought, $0.00 sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
Jun 5, 2026Vogt Frederick GInterim CEO & General CounselM15,625$0.00$0.00
Jun 5, 2026GRAF FINCKENSTEIN FRIEDRICHChief Medical OfficerM7,813$0.00$0.00
Jun 5, 2026GRAF FINCKENSTEIN FRIEDRICHChief Medical OfficerF3,976$4.23$16.8K
Jun 5, 2026GRAF FINCKENSTEIN FRIEDRICHChief Medical OfficerM7,813$0.00$0.00
Jun 5, 2026Puri Raj K.Chief Regulatory OfficerF3,843$4.23$16.3K
Jun 5, 2026Puri Raj K.Chief Regulatory OfficerM9,766$0.00$0.00
Jun 5, 2026Vogt Frederick GInterim CEO & General CounselF6,638$4.23$28.1K
Jun 5, 2026Vogt Frederick GInterim CEO & General CounselM15,625$0.00$0.00
Jun 5, 2026BILINSKY IGORChief Operating OfficerM7,813$0.00$0.00
Jun 5, 2026BILINSKY IGORChief Operating OfficerF3,976$4.23$16.8K
Jun 5, 2026BILINSKY IGORChief Operating OfficerM7,813$0.00$0.00
Jun 5, 2026Puri Raj K.Chief Regulatory OfficerM9,766$0.00$0.00
Jun 1, 2026Vogt Frederick GInterim CEO & General CounselF17,701$3.96$70.1K
Jun 1, 2026Vogt Frederick GInterim CEO & General CounselM41,668$0.00$0.00
Jun 1, 2026Puri Raj K.Chief Regulatory OfficerM5,469$0.00$0.00
Jun 1, 2026GRAF FINCKENSTEIN FRIEDRICHChief Medical OfficerM8,790$0.00$0.00
Jun 1, 2026Puri Raj K.Chief Regulatory OfficerF2,508$3.96$9.9K
Jun 1, 2026Puri Raj K.Chief Regulatory OfficerM5,469$0.00$0.00
Jun 1, 2026GRAF FINCKENSTEIN FRIEDRICHChief Medical OfficerM8,790$0.00$0.00
Jun 1, 2026BILINSKY IGORChief Operating OfficerM8,790$0.00$0.00
Jun 1, 2026BILINSKY IGORChief Operating OfficerF4,473$3.96$17.7K
Jun 1, 2026Vogt Frederick GInterim CEO & General CounselM41,668$0.00$0.00
Jun 1, 2026GRAF FINCKENSTEIN FRIEDRICHChief Medical OfficerF4,473$3.96$17.7K
Jun 1, 2026BILINSKY IGORChief Operating OfficerM8,790$0.00$0.00
May 11, 2026Kirby Daniel GordonChief Commercial OfficerM10,000$0.00$0.00
May 11, 2026Kirby Daniel GordonChief Commercial OfficerF2,435$3.70$9.0K
May 11, 2026Kirby Daniel GordonChief Commercial OfficerM10,000$0.00$0.00
Mar 9, 2026Kirby Daniel GordonChief Commercial OfficerA132,200$0.00$0.00
Mar 9, 2026GRAF FINCKENSTEIN FRIEDRICHChief Medical OfficerA58,750$0.00$0.00
Mar 9, 2026Puri Raj K.Chief Regulatory OfficerA117,500$0.00$0.00
Mar 9, 2026Vogt Frederick GInterim CEO & General CounselA235,000$0.00$0.00
Mar 9, 2026Roche Corleen M.Chief Financial OfficerA132,200$0.00$0.00
Mar 9, 2026BILINSKY IGORChief Operating OfficerA117,500$0.00$0.00
Mar 5, 2026Vogt Frederick GInterim CEO & General CounselM62,493$0.00$0.00
Mar 5, 2026Puri Raj K.Chief Regulatory OfficerM39,059$0.00$0.00
Mar 5, 2026BILINSKY IGORChief Operating OfficerM31,246$0.00$0.00
Mar 5, 2026BILINSKY IGORChief Operating OfficerM31,246$0.00$0.00
Mar 5, 2026Puri Raj K.Chief Regulatory OfficerM39,059$0.00$0.00
Mar 5, 2026Vogt Frederick GInterim CEO & General CounselM62,493$0.00$0.00
Mar 5, 2026GRAF FINCKENSTEIN FRIEDRICHChief Medical OfficerM31,246$0.00$0.00
Mar 5, 2026GRAF FINCKENSTEIN FRIEDRICHChief Medical OfficerM31,246$0.00$0.00
Mar 2, 2026Vogt Frederick GInterim CEO & General CounselM41,669$0.00$0.00
Mar 2, 2026BILINSKY IGORChief Operating OfficerM8,790$0.00$0.00
Mar 2, 2026Puri Raj K.Chief Regulatory OfficerM5,470$0.00$0.00
Mar 2, 2026Puri Raj K.Chief Regulatory OfficerM5,470$0.00$0.00
Mar 2, 2026GRAF FINCKENSTEIN FRIEDRICHChief Medical OfficerM8,790$0.00$0.00
Mar 2, 2026Vogt Frederick GInterim CEO & General CounselM52,087$0.00$0.00
Mar 2, 2026BILINSKY IGORChief Operating OfficerM12,307$0.00$0.00
Mar 2, 2026GRAF FINCKENSTEIN FRIEDRICHChief Medical OfficerM12,697$0.00$0.00
Feb 24, 2026Kirby Daniel GordonChief Commercial OfficerM150,000$0.00$0.00
Current analyst consensus: Strong Buy (81% buy). Based on 16 analysts: 3 strong buy, 10 buy, 3 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$8.80 mean target +126.8% upside Strong Buy (1.60)
$4.00 Low $14.00 High
MetricValue
Current Price$3.88
Target Low$4.00
Target Mean$8.80
Target Median$9.50
Target High$14.00
# Analysts10
RecommendationStrong Buy (1.60)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-0.13 $-0.16 $-0.11 59.2% +4.4% 1↑ 2↓ $0.1B 46.4% 8
Next Q
2026-09-30
$-0.12 $-0.17 $-0.09 50.1% +1.1% 1↑ 2↓ $0.1B 41.6% 8
Current FY
2026-12-31
$-0.56 $-0.72 $-0.46 48.2% -4.3% 2↑ 4↓ $0.4B 37.1% 8
Next FY
2027-12-31
$-0.32 $-0.46 $-0.23 43.5% -14.7% 2↑ 4↓ $0.5B 44.7% 7

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-0.135
7d ago$-0.135
30d ago$-0.141+0.006
60d ago$-0.130-0.005
90d ago$-0.130-0.005
4 analyst firms have rated this stock: 2 upgrades, 0 downgrades, 0 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
May 8, 2026 Chardan Capital MAINTAIN Buy Buy
Apr 10, 2026 Chardan Capital MAINTAIN Buy Buy
Mar 5, 2026 UBS MAINTAIN Neutral Neutral
Mar 3, 2026 Citizens UPGRADE Market Perform Market Outperform
Feb 25, 2026 Barclays MAINTAIN Overweight Overweight
Feb 25, 2026 Citizens UPGRADE Market Perform Market Outperform
Dec 17, 2025 Barclays MAINTAIN Overweight Overweight

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 202631030081%
May 1, 202631040076%
Apr 1, 202631040076%
Mar 1, 202631040076%
Feb 1, 20263951067%
Jan 1, 20263951067%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

70°
Bullish
Bearish Neutral Bullish
18 mentions 11 bullish 2 bearish 16 time periods

Reddit Sentiment History

DateMentionsSentimentBullishBearishThreads
May 26, 2026140° Cool011
May 26, 2026140° Cool011
Apr 22, 2026160° Warm101
Apr 22, 2026160° Warm101
Apr 14, 2026160° Warm101
Apr 14, 2026160° Warm101
Mar 6, 2026150° Neutral001
Mar 6, 2026150° Neutral001
Mar 6, 2026150° Neutral001
Feb 27, 2026160° Warm101
Feb 25, 2026160° Warm101
Feb 25, 2026160° Warm101
Feb 25, 2026150° Neutral001
Feb 24, 2026160° Warm101
Feb 24, 2026364° Warm203
Feb 23, 2026160° Warm101

Recent Reddit Threads

r/pennystocks Bearish 14d 19h ago
Biotech Short Watchlist Today: IOVA, BDTX, ESPR, SANA, FATE, ALT
▲ 1 💬 1 ⚡ 0.5
r/pennystocks Bullish 1mo ago
IOVA boom or bust?
▲ 1 💬 0 ⚡ 0.5
r/wallstreetbets Bullish 1mo ago
$IOVA
▲ 1 💬 1 ⚡ 0.5
r/pennystocks Neutral 3mo ago
IOVA stock
▲ 1 💬 0 ⚡ 0.5
r/pennystocks Neutral 3mo ago
Never thought I'd make post like this. $IOVA
▲ 1 💬 0 ⚡ 0.5
r/pennystocks Bullish 3mo ago
Biotech companies $IOVA and $NMRA DD
▲ 1 💬 1 ⚡ 0.0
r/wallstreetbets Bullish 3mo ago
IOVA heavy SI interest 🚀🚀
▲ 1 💬 4 ⚡ 0.0
r/wallstreetbets Bullish 3mo ago
IOVA short squeezing right now 🚀🚀🚀
▲ 1 💬 1 ⚡ 0.0
r/wallstreetbets Neutral 3mo ago
Thank you IOVA
▲ 39 💬 22 ⚡ 1.7
r/pennystocks Bullish 3mo ago
Have you heard about IOVA? It might be worth looking into it.
▲ 1 💬 0 ⚡ 0.0
r/wallstreetbets Bullish 3mo ago
IOVA Strong 25Q4 Earnings Call
▲ 72 💬 40 ⚡ 3.4
r/wallstreetbets Neutral 3mo ago
IOVA DD
▲ 1 💬 1 ⚡ 0.0
r/wallstreetbets Bullish 3mo ago
IOVA GAINZ 🚀🚀🚀
▲ 1 💬 1 ⚡ 0.0
r/options Bullish 3mo ago
Premium Higher than Share Price
▲ 16 💬 13 ⚡ 0.4
Jun 3, 2026
other
Iovance’s Amtagvi® (lifileucel) Granted Approval for the Treatment of Advanced Melanoma in Australia
<p align="center"><em>First T cell therapy for a solid tumor cancer and first treatment option approved </em><em>in Australia for advanced melanoma af
Jun 1, 2026
other
Iovance Biotherapeutics Announces Clearance of Investigational New Drug (IND) Application for IL-12 Tethered TIL Therapy IOV-5001
<p align="center"><em>Next-Generation Platform Expands into Solid Tumors </em><br><em>Representing 100,000+ U.S. Deaths Annually</em></p>
May 22, 2026
announcement
Iovance Biotherapeutics Reports Inducement Grants under NASDAQ Listing Rule 5635(c)(4)
<p>SAN CARLOS, Calif., May 22, 2026 (GLOBE NEWSWIRE) -- Iovance Biotherapeutics, Inc. (NASDAQ: IOVA) ("Iovance" or the “Company”), a biotechnology c
May 21, 2026
other
Iovance Biotherapeutics to Present at Upcoming Conference
<p>SAN CARLOS, Calif., May 21, 2026 (GLOBE NEWSWIRE) -- Iovance Biotherapeutics, Inc. (NASDAQ: IOVA), a biotechnology company focused on innovating,
May 16, 2026
Clinical Trial
Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors
Phase Phase 2 — TERMINATED
May 8, 2026
short_interest
FTD: IOVA — 224,151 shares ($0.8M) failed to deliver
Settlement: 20260508, Price: $3.55, FTD Value: $795,736.05, IOVANCE BIOTHERAPEUTICS INC CO
May 7, 2026
earnings
Iovance Biotherapeutics Highlights Positive First Quarter 2026 Results, Business Achievements and Corporate Updates
<p align="center"><em>1Q26 Total Revenue of ~$71M Delivers ~</em><em>45% Year-over-Year Growth</em></p>
May 7, 2026
earnings_calendar
IOVA Q1 2026 Earnings Scheduled — 2026-05-07
May 1, 2026
short_volume
Short Volume: IOVA — 58.8% short (3.6M / 6.2M)
Short: 3,629,164 | Exempt: 1,337 | TRF Vol: 6,168,784 | Short Ratio: 58.8% | Off-exchange volume (dark pool + OTC)
Apr 30, 2026
Clinical Trial
Lifileucel With Reduced Dose Fludarabine/Cyclophosphamide Lymphodepletion and Interleukin-2 for the Treatment of Patients With Unresectable or Metastatic Melanoma
Phase Phase 2 — COMPLETED
Apr 28, 2026
short_volume
Short Volume: IOVA — 61.7% short (4.6M / 7.5M)
Short: 4,635,122 | Exempt: 11,174 | TRF Vol: 7,514,831 | Short Ratio: 61.7% | Off-exchange volume (dark pool + OTC)
Apr 27, 2026
earnings
Iovance Biotherapeutics to Report First Quarter 2026 Financial Results and Corporate Updates on Thursday, May 7, 2026
<p>SAN CARLOS, Calif., April 27, 2026 (GLOBE NEWSWIRE) -- Iovance Biotherapeutics, Inc. (NASDAQ: IOVA), a biotechnology company focused on innovatin
Apr 22, 2026
short_volume
Short Volume: IOVA — 63.0% short (8.1M / 12.9M)
Short: 8,149,181 | Exempt: 47,547 | TRF Vol: 12,934,809 | Short Ratio: 63.0% | Off-exchange volume (dark pool + OTC)
Apr 17, 2026
activist
Iovance Biotherapeutics Reports Inducement Grants under NASDAQ Listing Rule 5635(c)(4)
<p>SAN CARLOS, Calif., April 17, 2026 (GLOBE NEWSWIRE) -- Iovance Biotherapeutics, Inc. (NASDAQ: IOVA) ("Iovance" or the “Company”), a biotechnology
Apr 13, 2026
short_volume
Short Volume: IOVA — 56.8% short (5.7M / 10.1M)
Short: 5,722,400 | Exempt: 58,069 | TRF Vol: 10,071,621 | Short Ratio: 56.8% | Off-exchange volume (dark pool + OTC)
Apr 10, 2026
short_volume
Short Volume: IOVA — 58.7% short (12.8M / 21.8M)
Short: 12,808,902 | Exempt: 52,252 | TRF Vol: 21,824,777 | Short Ratio: 58.7% | Off-exchange volume (dark pool + OTC)
Apr 8, 2026
short_volume
Short Volume: IOVA — 60.3% short (4.8M / 7.9M)
Short: 4,785,699 | Exempt: 11,950 | TRF Vol: 7,941,137 | Short Ratio: 60.3% | Off-exchange volume (dark pool + OTC)
Apr 1, 2026
Clinical Trial
Study of Lifileucel (LN-144), Autologous Tumor Infiltrating Lymphocytes, in the Treatment of Patients With Metastatic Melanoma
Phase Phase 2 — COMPLETED