GYRE

GYRE THERAPEUTICS, INC.

Nasdaq · Pharmaceutical Preparations · Inc. DE · CIK 0001124105
$5.93 -2.15% $575.4M
Insider Selling Cluster (2 insiders)High Impact Filing (7/10)3 New Institutional Positions
Vol
Market Cap$575.4M
Cap SizeSmall Cap
Inst. Holders27 funds
Inst. Value$18.0M
Inst. Activity3 buys / 2 sells
Insider Activity0B / 12S
Insider Net $-$821.2K
SEC Reports4
Press Releases2
Exchange Nasdaq·Sector Pharmaceutical Preparations·Inc. DE·CIK 0001124105·Prev Close $6.06

Recent Activity

Jun 10, 2026 Insider
Ye Weiguo acquired via exercise 6,418 shares
Chief Operating Officer @ $0.7500 ($4.8K)
Jun 10, 2026 Insider
Ye Weiguo sold 6,418 shares
Chief Operating Officer @ $6.21 ($39.9K)
Jun 9, 2026 Insider
Ye Weiguo acquired via exercise 14,500 shares
Chief Operating Officer @ $0.7500 ($10.9K)
Jun 2, 2026 SEC
Gyre Therapeutics filed an 8-K furnishing an updated corporate investor presentation. The presentation highlights the co
8-K — Impact 4/10
May 14, 2026 SEC
Gyre Therapeutics filed an 8-K furnishing an investor presentation under Item 7.01, to be presented at a scientific conf
8-K — Impact 5/10
May 8, 2026 earnings_calendar
GYRE Q1 2026 Earnings Scheduled — 2026-05-08
May 4, 2026 SEC
Gyre Therapeutics closed its all-stock acquisition of Cullgen Inc. on May 4, 2026, in a transaction valued at approximat
8-K, DEFA14A — Impact 7/10
Inst.
DIMENSIONAL FUND ADVISORS LP — DOUBLED
25,268 shares ($176.1K)

Price Targets

Historical data — last covering-analyst action Oct 2025. No current recommendation available.
$18.67 (Oct 2025)
Current $5.93 Low $18.00 Median $18.00 High $20.00 3 analysts
$18.00 $20.00

Analyst Ratings

Historical distribution89% buy · 9 analysts · last covering-analyst action Oct 2025
3Strong Buy
5Buy
1Hold
0Sell
0Strong Sell
Historical Analyst Actions
DateFirmActionRating
Oct 10, 2025 Jefferies INITIATE Buy
Aug 26, 2025 HC Wainwright & Co. INITIATE Buy

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-0.06 $-0.09 — $0.00 0% YoY 3
Next Q $-0.07 $-0.13 — $-0.02 -344% YoY 3
Current FY $-0.29 $-0.45 — $-0.12 -1550% YoY 3
Next FY $-0.12 $-0.23 — $0.00 60% YoY 2

Top Institutional Holders

FundValueMove
VANGUARD CAPITAL MANAGEMENT LLC$6.9M
BlackRock, Inc.$5.3M
STATE STREET CORP$1.5MADD
CHARLES SCHWAB INVESTMENT MANAGEMENT$1.2MADD
VANGUARD FIDUCIARY TRUST CO$959.6K

Recent Insider Trades

DateInsiderTypeValue
Jun 10, 2026Ye WeiguoM$4.8K
Jun 10, 2026Ye WeiguoSELL$39.9K
Jun 9, 2026Ye WeiguoM$10.9K
Jun 9, 2026Ye WeiguoSELL$89.0K
Jun 8, 2026Luo YingA$0.00
27 institutional holders with $18.0M total value (2,580,373 shares) as of 2026-Q1. Top holders: VANGUARD, BlackRock,, STATE. Net buying activity: 3 institutions added/increased vs 2 reduced.

Top Institutional Holders — 2026-Q1

#FundSharesValue% of TrackedLast Move
1VANGUARD CAPITAL MANAGEMENT LLC984,204$6.9M38.1%
2BlackRock, Inc.758,630$5.3M29.4%
3STATE STREET CORP216,326$1.5M8.4%ADD +38.0%
4CHARLES SCHWAB INVESTMENT MANAGEMENT INC165,238$1.2M6.4%ADD +37.1%
5VANGUARD FIDUCIARY TRUST CO137,682$959.6K5.3%
6GOLDMAN SACHS GROUP INC73,122$509.7K2.8%
7VANGUARD PORTFOLIO MANAGEMENT LLC69,814$486.6K2.7%
8DIMENSIONAL FUND ADVISORS LP25,268$176.1K1.0%DOUBLED +131.8%
9ALLIANCEBERNSTEIN L.P.21,830$154.1K0.9%
10STRS OHIO21,100$147.1K0.8%ADD +58.6%
11FMR LLC18,717$130.5K0.7%ADD +81.6%
12Brevan Howard Capital Management LP13,808$96.2K0.5%
13RHUMBLINE ADVISERS13,116$91.4K0.5%ADD +45.3%
14DEUTSCHE BANK AG\10,613$74.0K0.4%
15BANK OF AMERICA CORP /DE/10,538$73.5K0.4%ADD +45.9%
16Vanguard Global Advisers, LLC9,983$69.6K0.4%
17MORGAN STANLEY8,641$60.2K0.3%NEAR_EXIT -84.1%
18MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.5,617$39.1K0.2%ADD +30.4%
19ROYAL BANK OF CANADA5,605$39.0K0.2%DOUBLED +1497.4%
20WELLS FARGO & COMPANY/MN4,290$29.9K0.2%DOUBLED +132.4%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
DIMENSIONAL FUND ADVISORS LPDOUBLED10,90325,268+131.8%$176.1K2026-Q1
FMR LLCADD10,30418,717+81.6%$130.5K2026-Q1
MORGAN STANLEYNEAR_EXIT54,4988,641-84.1%$60.2K2026-Q1
Russell Investments Group, Ltd.TRIM2,0031,124-43.9%$7.8K2026-Q1
CWM, LLCDOUBLED36104+188.9%$725.002026-Q1
CHARLES SCHWAB INVESTMENT MANAGEMENT INCADD123,386169,158+37.1%$1.2M2025-Q4
MORGAN STANLEYDOUBLED8,98154,498+506.8%$384.8K2025-Q4
STATE OF WISCONSIN INVESTMENT BOARDTRIM39,00024,800-36.4%$175.1K2025-Q4
WELLS FARGO & COMPANY/MNDOUBLED5,55812,919+132.4%$91.2K2025-Q4
BANK OF AMERICA CORP /DE/ADD6,6879,759+45.9%$68.9K2025-Q4
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.ADD4,2035,481+30.4%$38.7K2025-Q4
Russell Investments Group, Ltd.ADD1,1242,003+78.2%$14.1K2025-Q4
Legal & General Group PlcADD8601,405+63.4%$9.9K2025-Q4
CWM, LLCTRIM12343-65.0%2025-Q3
UBS Group AGDOUBLED8,63922,962+165.8%$171.3K2025-Q3
STRS OHIOADD13,30021,100+58.6%$157.4K2025-Q3
BARCLAYS PLCTRIM24,00413,396-44.2%$99.9K2025-Q3
MORGAN STANLEYTRIM35,2588,981-74.5%$67.0K2025-Q3
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.TRIM7,4134,203-43.3%$31.4K2025-Q3
Legal & General Group PlcTRIM1,513860-43.2%$6.4K2025-Q3
NISA INVESTMENT ADVISORS, LLCADD59102+72.9%$761.002025-Q3
STATE STREET CORPADD128,773177,768+38.0%$1.3M2025-Q2
RHUMBLINE ADVISERSADD11,14116,186+45.3%$119.0K2025-Q2
UBS Group AGTRIM24,3068,639-64.5%$63.5K2025-Q2
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.ADD4,1697,413+77.8%$54.5K2025-Q2
6 unique insiders with 27 transactions. Net insider value: -$821.2K ($0.00 bought, $821.2K sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
Jun 10, 2026Ye WeiguoChief Operating OfficerEXERCISE6,418$0.7500$4.8K
Jun 10, 2026Ye WeiguoChief Operating OfficerSELL6,418$6.21$39.9K
Jun 9, 2026Ye WeiguoChief Operating OfficerEXERCISE14,500$0.7500$10.9K
Jun 9, 2026Ye WeiguoChief Operating OfficerSELL14,500$6.14$89.0K
Jun 8, 2026Luo YingChief Executive OfficerAWARD120,000
Jun 8, 2026Bergmann Joshua BenjaminGC and Corporate SecretaryAWARD50,000
Jun 5, 2026Ye WeiguoChief Operating OfficerEXERCISE15,401$0.7500$11.6K
Jun 5, 2026Ye WeiguoChief Operating OfficerSELL15,401$6.40$98.6K
Jun 4, 2026Ye WeiguoChief Operating OfficerSELL19,575$6.13$120.0K
Jun 4, 2026Ye WeiguoChief Operating OfficerEXERCISE19,575$0.7500$14.7K
May 21, 2026Ye WeiguoChief Operating OfficerEXERCISE12,820$0.7500$9.6K
May 21, 2026Ye WeiguoChief Operating OfficerSELL12,820$6.15$78.8K
May 20, 2026Ye WeiguoChief Operating OfficerEXERCISE9,400$0.7500$7.0K
May 20, 2026Ye WeiguoChief Operating OfficerSELL9,400$6.15$57.8K
May 19, 2026Ye WeiguoChief Operating OfficerEXERCISE9,120$0.7500$6.8K
May 19, 2026Ye WeiguoChief Operating OfficerSELL9,120$6.37$58.1K
May 18, 2026Ye WeiguoChief Operating OfficerEXERCISE200$0.7500$150.00
May 18, 2026Ye WeiguoChief Operating OfficerSELL200$6.62$1.3K
May 15, 2026Ye WeiguoChief Operating OfficerEXERCISE13,100$0.7500$9.8K
May 15, 2026Ye WeiguoChief Operating OfficerSELL13,100$6.65$87.1K
May 14, 2026Ye WeiguoChief Operating OfficerSELL15,580$6.91$107.7K
May 14, 2026Ye WeiguoChief Operating OfficerEXERCISE15,580$0.7500$11.7K
May 14, 2026Zhang PingDirectorD250,000
May 6, 2026Luo YingChief Executive OfficerSELL10,136$8.04$81.5K
May 5, 2026Luo YingChief Executive OfficerSELL179$8.01$1.4K
May 4, 2026Eastling Thomas WilsonChief Financial OfficerAWARD95,060
May 4, 2026GNI Group Ltd.10%+ OwnerJ458,120
Historical analyst distribution (last covering-analyst action Oct 2025): 89% buy across 9 analysts — 3 strong buy, 5 buy, 1 hold, 0 sell, 0 strong sell. No current recommendation available.

Analyst Price Targets

Historical data — last covering-analyst action Oct 2025. No current recommendation available.
$18.67 mean target (Oct 2025)
$18.00 Low $20.00 High
MetricValue
Current Price$5.93
Target Low$18.00
Target Mean$18.67
Target Median$18.00
Target High$20.00
# Analysts3
Recommendation— (no recent coverage)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-0.06 $-0.09 $0.00 0.0% 0↑ 1↓ $0.0B -1.1% 3
Next Q
2026-09-30
$-0.07 $-0.13 $-0.02 -344.4% 0↑ 2↓ $0.0B -13.4% 3
Current FY
2026-12-31
$-0.29 $-0.45 $-0.12 -1550.0% 0↑ 3↓ $0.1B -12.3% 3
Next FY
2027-12-31
$-0.12 $-0.23 $0.00 60.3% 0↑ 2↓ $0.1B 27.8% 2

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-0.057
7d ago$0.000-0.057
30d ago$0.000-0.057
60d ago$0.050-0.107
90d ago$0.050-0.107
2 analyst firms have rated this stock: 0 upgrades, 0 downgrades, 2 initiations.

Historical Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
Oct 10, 2025 Jefferies INITIATE Buy
Aug 26, 2025 HC Wainwright & Co. INITIATE Buy

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 20263510089%
May 1, 20263510089%
Apr 1, 20263510089%
Mar 1, 20263510089%
Feb 1, 20263510089%
Jan 1, 20263510089%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

No Reddit sentiment data available yet. Sentiment is analyzed from Reddit investment communities on a rolling basis.

May 8, 2026
earnings_calendar
GYRE Q1 2026 Earnings Scheduled — 2026-05-08
May 7, 2026
earnings
Gyre Therapeutics Reports First Quarter 2026 Results and Provides Business Update
Gyre Therapeutics Reports First Quarter 2026 Results and Provides Business Update
May 4, 2026
m_and_a
Gyre Therapeutics Completes Acquisition of Cullgen to Create U.S.- and China-based Fully Integrated Biopharmaceutical Company
Gyre Therapeutics Completes Acquisition of Cullgen to Create U.S.- and China-based Fully Integrated Biopharmaceutical Company
Mar 12, 2026
earnings
Gyre Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results and Provides Business Update
Gyre Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results and Provides Business Update