CYTK

CYTOKINETICS INC

Nasdaq · Pharmaceutical Preparations · CIK 0001061983
$68.45 +0.81% $8.4B
Insider Selling Cluster (5 insiders)High Impact Filing (7/10)3 New Institutional Positions
Vol
Market Cap$8.4B
Cap SizeMid Cap
Analyst ConsensusStrong Buy (86%)
Inst. Holders9 funds
Inst. Value$2.0B
Inst. Activity3 buys / 1 sells
Insider Activity0B / 14S
Insider Net $-$10.2M
SEC Reports12
Press Releases6
Exchange Nasdaq·Sector Pharmaceutical Preparations·CIK 0001061983·Prev Close $67.90

Recent Activity

Nov 14, 2026 fda_pdufa
PDUFA: CYTK — aficamten in obstructive hypertrophic cardiomyopathy — 2026-11-14
FDA target action date 2026-11-14 for CYTK (CYTOKINETICS INC). Drug: aficamten. Indication: obstruct
Jun 9, 2026 Insider
Malik Fady Ibraham sold 3,500 shares
EVP Research & Development @ $7.80 ($27.3K)
Jun 9, 2026 Insider
Malik Fady Ibraham sold 3,500 shares
EVP Research & Development @ $67.98 ($237.9K)
Jun 9, 2026 Insider
Malik Fady Ibraham sold 3,500 shares
EVP Research & Development @ $0.00 ($0.00)
Jun 1, 2026 SEC
Two insiders at Cytokinetics, including the President & CEO, sold a total of $949K in open-market sales over a one-week
CLUSTER — Impact 3/10
May 20, 2026 SEC
CEO Robert Blum and EVP Fady Malik sold a total of $849K in open-market transactions within a week of a $700M equity off
CLUSTER — Impact 3/10
May 5, 2026 SEC
Cytokinetics filed a preliminary prospectus supplement for a $650M common stock offering, underwritten by Morgan Stanley
424B5 — Impact 6/10
Inst.
NORGES BANK — NEW
807,070 shares ($51.3M)

Price Targets

$104.70 +53.0% upside Strong Buy
Current $68.45 Low $69.00 Median $104.00 High $146.00 20 analysts
$69.00 $146.00

Analyst Ratings

Strong Buy86% buy · 28 analysts
6Strong Buy
18Buy
4Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
May 19, 2026 Citigroup INITIATE Buy
May 12, 2026 JP Morgan MAINTAIN Overweight → Overweight
May 11, 2026 HC Wainwright & Co. MAINTAIN Buy → Buy
May 7, 2026 Wells Fargo MAINTAIN Overweight → Overweight
May 6, 2026 Stifel MAINTAIN Buy → Buy

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-1.64 ▲ +2.2% $-2.02 — $-1.26 -47% YoY 15
Next Q $-1.59 ▲ +3.6% $-1.90 — $-1.05 -3% YoY 15
Current FY $-6.43 ▲ +2.2% $-7.47 — $-4.80 2% YoY 15
Next FY $-4.75 ▲ +4.4% $-5.61 — $-3.39 26% YoY 14

Top Institutional Holders

FundValueMove
FMR LLC$813.8M
VANGUARD GROUP INC$765.5M
BANK OF AMERICA CORP$186.9M
CHARLES SCHWAB INVESTMENT MANAGEMENT$87.9MNEW
MORGAN STANLEY$80.4MADD

Recent Insider Trades

DateInsiderTypeValue
Jun 9, 2026Malik FadyM$27.3K
Jun 9, 2026Malik FadySELL$237.9K
Jun 9, 2026Malik FadyM$0.00
Jun 1, 2026PARSHALL BSELL$370.4K
Jun 1, 2026Callos AndrewM$348.9K
9 institutional holders with $2.0B total value (31,860,483 shares) as of 2025-Q4. Top holders: FMR, VANGUARD, BANK. Net buying activity: 3 institutions added/increased vs 1 reduced.

Top Institutional Holders — 2025-Q4

#FundSharesValue% of TrackedLast Move
1FMR LLC12,807,752$813.8M40.2%
2VANGUARD GROUP INC12,048,131$765.5M37.8%
3BANK OF AMERICA CORP /DE/2,941,152$186.9M9.2%
4CHARLES SCHWAB INVESTMENT MANAGEMENT INC1,383,437$87.9M4.3%NEW
5MORGAN STANLEY1,265,301$80.4M4.0%ADD +36.1%
6NORGES BANK807,070$51.3M2.5%NEW
7TWO SIGMA INVESTMENTS, LP274,017$17.4M0.9%NEW
8RENAISSANCE TECHNOLOGIES LLC172,067$10.9M0.5%TRIM -40.7%
9WELLS FARGO & COMPANY/MN161,556$10.3M0.5%ADD +65.6%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
NORGES BANKNEW807,070$51.3M2025-Q4
TWO SIGMA INVESTMENTS, LPNEW274,017$17.4M2025-Q4
RENAISSANCE TECHNOLOGIES LLCTRIM289,967172,067-40.7%$10.9M2025-Q4
WELLS FARGO & COMPANY/MNADD97,560161,556+65.6%$10.3M2025-Q4
UBS Group AGTRIM3,070,6651,823,051-40.6%$100.2M2025-Q3
MORGAN STANLEYADD1,118,0801,521,186+36.1%$83.6M2025-Q3
RENAISSANCE TECHNOLOGIES LLCDOUBLED10,167289,967+2752.0%$15.9M2025-Q3
NORGES BANKEXIT1,184,0720-100.0%$0.002025-Q3
UBS Group AGADD2,134,2193,070,665+43.9%$101.5M2025-Q2
NORGES BANKNEW1,184,072$39.1M2025-Q2
WELLS FARGO & COMPANY/MNADD73,96695,350+28.9%$3.2M2025-Q2
RENAISSANCE TECHNOLOGIES LLCNEAR_EXIT120,66710,167-91.6%$335.9K2025-Q2
TWO SIGMA INVESTMENTS, LPEXIT44,1560-100.0%$0.002025-Q2
UBS Group AGADD1,201,9992,134,219+77.6%$85.8M2025-Q1
RENAISSANCE TECHNOLOGIES LLCTRIM192,167120,667-37.2%$4.8M2025-Q1
TWO SIGMA INVESTMENTS, LPTRIM91,17144,156-51.6%$1.8M2025-Q1
NORGES BANKEXIT989,7210-100.0%$0.002025-Q1
CITADEL ADVISORS LLCADD1,323,7911,761,945+33.1%$82.9M2024-Q4
UBS Group AGDOUBLED314,1591,201,999+282.6%$56.5M2024-Q4
WELLS FARGO & COMPANY/MNADD57,53473,782+28.2%$3.5M2024-Q4
CHARLES SCHWAB INVESTMENT MANAGEMENT INCNEW1,321,391$69.8M2024-Q3
13 unique insiders with 14 transactions. Net insider value: -$10.2M ($0.00 bought, $10.2M sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
Jun 9, 2026Malik Fady IbrahamEVP Research & DevelopmentM3,500$7.80$27.3K
Jun 9, 2026Malik Fady IbrahamEVP Research & DevelopmentSELL3,500$67.98$237.9K
Jun 9, 2026Malik Fady IbrahamEVP Research & DevelopmentM3,500$0.00$0.00
Jun 1, 2026PARSHALL B LYNNEDirectorSELL5,000$74.08$370.4K
Jun 1, 2026Callos AndrewEVP, Chief Commercial OfficerM15,000$23.26$348.9K
Jun 1, 2026Callos AndrewEVP, Chief Commercial OfficerSELL15,000$74.08$1.1M
Jun 1, 2026Callos AndrewEVP, Chief Commercial OfficerM15,000$0.00$0.00
Jun 1, 2026Kaye Edward M. MDDirectorSELL2,933$76.09$223.2K
May 27, 2026Wysenski NancyDirectorA2,851$0.00$0.00
May 27, 2026Wysenski NancyDirectorA4,301$0.00$0.00
May 27, 2026WIERENGA WENDELLDirectorA2,851$0.00$0.00
May 27, 2026WIERENGA WENDELLDirectorA4,301$0.00$0.00
May 27, 2026Landry Robert EDirectorA2,851$0.00$0.00
May 27, 2026Landry Robert EDirectorA4,301$0.00$0.00
May 27, 2026PARSHALL B LYNNEDirectorA2,851$0.00$0.00
May 27, 2026PARSHALL B LYNNEDirectorA4,301$0.00$0.00
May 27, 2026Kaye Edward M. MDDirectorA2,851$0.00$0.00
May 27, 2026Kaye Edward M. MDDirectorA4,301$0.00$0.00
May 27, 2026HENDERSON JOHN TDirectorA2,851$0.00$0.00
May 27, 2026HENDERSON JOHN TDirectorA4,301$0.00$0.00
May 27, 2026Harrington Robert ArthurDirectorA2,851$0.00$0.00
May 27, 2026Harrington Robert ArthurDirectorA4,301$0.00$0.00
May 27, 2026Daly James MDirectorA2,851$0.00$0.00
May 27, 2026Daly James MDirectorA4,301$0.00$0.00
May 27, 2026Bhanji MunaDirectorA2,851$0.00$0.00
May 27, 2026Bhanji MunaDirectorA4,301$0.00$0.00
May 27, 2026Blum Robert IPresident & CEOSELL7,500$77.21$579.1K
May 19, 2026Malik Fady IbrahamEVP Research & DevelopmentM3,500$7.80$27.3K
May 19, 2026Malik Fady IbrahamEVP Research & DevelopmentSELL3,500$75.69$264.9K
May 19, 2026Malik Fady IbrahamEVP Research & DevelopmentM3,500$0.00$0.00
May 14, 2026Blum Robert IPresident & CEOSELL7,500$77.92$584.4K
May 5, 2026Malik Fady IbrahamEVP Research & DevelopmentM3,500$7.80$27.3K
May 5, 2026Malik Fady IbrahamEVP Research & DevelopmentSELL3,500$77.37$270.8K
May 5, 2026Malik Fady IbrahamEVP Research & DevelopmentM3,500$0.00$0.00
May 5, 2026Callos AndrewEVP, Chief Commercial OfficerM11,333$39.13$443.5K
May 5, 2026Callos AndrewEVP, Chief Commercial OfficerSELL11,333$77.25$875.5K
May 5, 2026Callos AndrewEVP, Chief Commercial OfficerM11,333$0.00$0.00
May 5, 2026Lee SungEVP, Chief Financial OfficerSELL23,906$76.87$1.8M
May 5, 2026HENDERSON JOHN TDirectorM20,000$7.61$152.2K
May 5, 2026HENDERSON JOHN TDirectorSELL20,000$75.97$1.5M
May 5, 2026HENDERSON JOHN TDirectorM20,000$0.00$0.00
May 5, 2026WIERENGA WENDELLDirectorM4,032$12.40$50.0K
May 5, 2026WIERENGA WENDELLDirectorSELL4,032$75.00$302.4K
May 5, 2026WIERENGA WENDELLDirectorM4,032$0.00$0.00
May 1, 2026Callos AndrewEVP, Chief Commercial OfficerM15,857$37.63$596.7K
May 1, 2026Callos AndrewEVP, Chief Commercial OfficerSELL15,857$65.00$1.0M
May 1, 2026Callos AndrewEVP, Chief Commercial OfficerM15,857$0.00$0.00
Apr 30, 2026Callos AndrewEVP, Chief Commercial OfficerM15,000$23.26$348.9K
Apr 30, 2026Callos AndrewEVP, Chief Commercial OfficerSELL15,000$63.26$948.9K
Apr 30, 2026Callos AndrewEVP, Chief Commercial OfficerM15,000$0.00$0.00
12 SEC filing reports analyzed. Sentiment: 0 bullish, 3 bearish, 3 mixed, 6 neutral. Avg impact: 4.5/10.
NEUTRAL CLUSTER 3/10
Two insiders at Cytokinetics, including the President & CEO, sold a total of $949K in open-market sa
Jun 1, 2026
NEUTRAL CLUSTER 3/10
CEO Robert Blum and EVP Fady Malik sold a total of $849K in open-market transactions within a week o
May 20, 2026
MIXED 424B5 6/10
Cytokinetics filed a preliminary prospectus supplement for a $650M common stock offering, underwritt
May 5, 2026
MIXED CLUSTER 4/10
Multiple CYTK insiders, including CFO and CCO, sold shares totaling $4.53M on the same day as Q1 202
May 5, 2026
NEUTRAL CLUSTER 3/10
Two insiders at Cytokinetics sold a combined $2.39M in open-market stock on May 5, 2026, the same da
May 5, 2026
NEUTRAL 8-K 3/10
Cytokinetics released a corporate presentation updating on commercial launch progress of MYQORZO (af
May 5, 2026
NEUTRAL PRESS-RELEASE 3/10
Cytokinetics announced a scheduled date for its Q1 2026 earnings release on May 5, 2026, with a subs
Apr 21, 2026
BEARISH CLUSTER 7/10
Two top executives at Cytokinetics, including the CEO and Chief Commercial Officer, sold nearly $1 m
Apr 15, 2026
BEARISH CLUSTER 6/10
Three corporate insiders at Cytokinetics sold shares in the past week, totaling $964K in open-market
Apr 8, 2026
NEUTRAL 144 3/10
Fady Malik, an officer at Cytokinetics, filed a Form 144 to notify intent to sell 22,000 shares of c
Apr 7, 2026
BEARISH CLUSTER 6/10
Two top executives at Cytokinetics, including CEO Robert Blum, sold shares in a coordinated 7-day wi
Apr 1, 2026
MIXED 8-K 7/10
Cytokinetics reported its transition to a commercial-stage company following FDA, China, and EU appr
Feb 24, 2026
Current analyst consensus: Strong Buy (86% buy). Based on 28 analysts: 6 strong buy, 18 buy, 4 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$104.70 mean target +53.0% upside Strong Buy (1.59)
$69.00 Low $146.00 High
MetricValue
Current Price$68.45
Target Low$69.00
Target Mean$104.70
Target Median$104.00
Target High$146.00
# Analysts20
RecommendationStrong Buy (1.59)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-1.64 $-2.02 $-1.26 -46.5% +2.2% 9↑ 3↓ $0.0B -74.2% 15
Next Q
2026-09-30
$-1.59 $-1.90 $-1.05 -3.1% +3.6% 9↑ 4↓ $0.0B 1291.9% 15
Current FY
2026-12-31
$-6.43 $-7.47 $-4.80 1.6% +2.2% 8↑ 5↓ $0.1B 24.1% 15
Next FY
2027-12-31
$-4.75 $-5.61 $-3.39 26.1% +4.4% 8↑ 4↓ $0.4B 254.5% 14

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-1.641
7d ago$-1.668+0.027
30d ago$-1.677+0.036
60d ago$-1.663+0.023
90d ago$-1.530-0.111
16 analyst firms have rated this stock: 1 upgrades, 0 downgrades, 2 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
May 19, 2026 Citigroup INITIATE Buy
May 12, 2026 JP Morgan MAINTAIN Overweight Overweight
May 11, 2026 HC Wainwright & Co. MAINTAIN Buy Buy
May 7, 2026 Wells Fargo MAINTAIN Overweight Overweight
May 6, 2026 Stifel MAINTAIN Buy Buy
May 6, 2026 Morgan Stanley MAINTAIN Overweight Overweight
May 6, 2026 RBC Capital MAINTAIN Outperform Outperform
May 5, 2026 Needham MAINTAIN Buy Buy
Apr 10, 2026 Wells Fargo INITIATE Overweight
Apr 6, 2026 Barclays MAINTAIN Overweight Overweight
Mar 18, 2026 Mizuho MAINTAIN Outperform Outperform
Mar 17, 2026 JP Morgan MAINTAIN Overweight Overweight
Mar 6, 2026 UBS MAINTAIN Neutral Neutral
Feb 26, 2026 Leerink Partners MAINTAIN Outperform Outperform
Feb 25, 2026 Citizens MAINTAIN Market Outperform Market Outperform
Feb 25, 2026 Needham MAINTAIN Buy Buy
Feb 20, 2026 RBC Capital MAINTAIN Outperform Outperform
Feb 3, 2026 Truist Securities MAINTAIN Buy Buy
Jan 21, 2026 B. Riley Securities MAINTAIN Buy Buy
Jan 21, 2026 RBC Capital REITERATE Outperform Outperform
Jan 20, 2026 JP Morgan MAINTAIN Overweight Overweight
Dec 23, 2025 Morgan Stanley MAINTAIN Overweight Overweight
Dec 22, 2025 RBC Capital MAINTAIN Outperform Outperform
Dec 22, 2025 Barclays MAINTAIN Overweight Overweight
Dec 22, 2025 Citizens MAINTAIN Market Outperform Market Outperform
Dec 22, 2025 Needham MAINTAIN Buy Buy
Dec 22, 2025 HC Wainwright & Co. MAINTAIN Buy Buy
Dec 19, 2025 Goldman Sachs UPGRADE Neutral Buy
Dec 12, 2025 Needham REITERATE Buy Buy

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 202661840086%
May 1, 202651840085%
Apr 1, 202651740085%
Mar 1, 202651740085%
Feb 1, 202651740085%
Jan 1, 202651740085%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

No Reddit sentiment data available yet. Sentiment is analyzed from Reddit investment communities on a rolling basis.

Nov 14, 2026
fda_pdufa
PDUFA: CYTK — aficamten in obstructive hypertrophic cardiomyopathy — 2026-11-14
FDA target action date 2026-11-14 for CYTK (CYTOKINETICS INC). Drug: aficamten. Indication: obstructive hypertrophic cardiomyopathy. sNDA for aficamte
Jun 10, 2026
Clinical Trial
Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCM
Phase Phase 3 — COMPLETED
Jun 8, 2026
other
Cytokinetics Announces Call for Proposals for Annual Corporate Giving Program
<p align="center"><em>Program to Provide Donations to Non-Profit Organizations Aligned with Corporate Values</em></p>
Jun 3, 2026
short_volume
Short Volume: CYTK — 57.3% short (0.3M / 0.5M)
Short: 307,493 | Exempt: 25 | TRF Vol: 536,903 | Short Ratio: 57.3% | Off-exchange volume (dark pool + OTC)
Jun 2, 2026
short_volume
Short Volume: CYTK — 67.1% short (0.4M / 0.6M)
Short: 383,361 | Exempt: 4,899 | TRF Vol: 571,649 | Short Ratio: 67.1% | Off-exchange volume (dark pool + OTC)
Jun 1, 2026
other
Cytokinetics Launches MYQORZO® (aficamten) in European Union, with First Commercial Availability in Germany
<p align="center"><em>European Launch Follows Strong U.S. Start</em></p>
Jun 1, 2026
short_volume
Short Volume: CYTK — 56.7% short (0.4M / 0.7M)
Short: 382,002 | Exempt: 670 | TRF Vol: 673,910 | Short Ratio: 56.7% | Off-exchange volume (dark pool + OTC)
May 29, 2026
short_volume
Short Volume: CYTK — 55.7% short (0.3M / 0.6M)
Short: 315,771 | Exempt: 152 | TRF Vol: 566,633 | Short Ratio: 55.7% | Off-exchange volume (dark pool + OTC)
May 27, 2026
other
Cytokinetics to Participate in June Investor Conferences
<p align="justify">SOUTH SAN FRANCISCO, Calif., May 27, 2026 (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced that memb
May 27, 2026
short_volume
Short Volume: CYTK — 78.0% short (0.6M / 0.8M)
Short: 600,980 | Exempt: 28,782 | TRF Vol: 770,832 | Short Ratio: 78.0% | Off-exchange volume (dark pool + OTC)
May 20, 2026
routine
Cytokinetics to Hold Annual Meeting of Stockholders
<p align="justify">SOUTH SAN FRANCISCO, Calif., May 20, 2026 (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced that its
May 19, 2026
short_volume
Short Volume: CYTK — 56.7% short (0.6M / 1.0M)
Short: 588,687 | Exempt: 3,493 | TRF Vol: 1,038,550 | Short Ratio: 56.7% | Off-exchange volume (dark pool + OTC)
May 18, 2026
other
Cytokinetics Announces Inducement Grants Under Nasdaq Listing Rule 5635(C)(4)
<p align="justify">SOUTH SAN FRANCISCO, Calif., May 18, 2026 (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced that on M
May 15, 2026
short_volume
Short Volume: CYTK — 76.6% short (0.5M / 0.6M)
Short: 461,233 | Exempt: 942 | TRF Vol: 601,857 | Short Ratio: 76.6% | Off-exchange volume (dark pool + OTC)
May 13, 2026
short_interest
FTD: CYTK — 27,719 shares ($2.1M) failed to deliver
Settlement: 20260513, Price: $74.81, FTD Value: $2,073,658.39, CYTOKINETICS INC COM STK NEW (
May 12, 2026
other
Cytokinetics to Participate in the 2026 RBC Capital Markets Global Healthcare Conference
<p align="justify">SOUTH SAN FRANCISCO, Calif., May 12, 2026 (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced that memb
Mar 30, 2026
Clinical Trial
Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic nHCM
Phase Phase 3 — ACTIVE_NOT_RECRUITING