COGT

Cogent Biosciences, Inc.

Nasdaq · Pharmaceutical Preparations · Inc. DE · CIK 0001622229
$33.07 -0.30% $5.7B
24 New Institutional Positions7 Institutional Exits
Vol
Market Cap$5.7B
Cap SizeMid Cap
Analyst ConsensusStrong Buy (84%)
Inst. Holders50 funds
Inst. Value$4.1B
Inst. Activity24 buys / 7 sells
Insider Activity0B / 1S
Insider Net $-$242.6M
SEC Reports1
Press Releases6
Exchange Nasdaq·Sector Pharmaceutical Preparations·Inc. DE·CIK 0001622229·Prev Close $33.17

Recent Activity

Dec 30, 2026 fda_pdufa
PDUFA: COGT — bezuclastinib in NonAdvanced Systemic Mastocytosis (NonAdvSM) — 2026-12-30
FDA target action date 2026-12-30 for COGT (Cogent Biosciences, Inc.). Drug: bezuclastinib. Indicati
Jun 12, 2026 Press
Cogent Biosciences reported updated Phase 2 APEX trial results for bezuclastinib in advanced systemic mastocytosis (AdvS
Impact 7/10
Jun 12, 2026 Press
Cogent Biosciences presented preclinical data for its novel JAK2 V617F mutant-selective inhibitor CGT1145 at the EHA Con
Impact 4/10
Jun 9, 2026 Insider
Ros Matthew was granted 17,901 shares
Director
Jun 9, 2026 Insider
Harwin Peter Evan was granted 17,901 shares
Director
Jun 9, 2026 Insider
Ferrante Karen Jean was granted 17,901 shares
Director
May 5, 2026 SEC
Cogent Biosciences reported Q1 2026 net loss of $97.4M, wider than the $72.0M loss in Q1 2025, driven by increased R&D a
8-K — Impact 4/10
Inst.
JANUS HENDERSON GROUP PLC — ADD
5,965,125 shares ($229.6M)

Price Targets

$54.25 +64.0% upside Strong Buy
Current $33.07 Low $35.00 Median $55.00 High $72.00 12 analysts
$35.00 $72.00

Analyst Ratings

Strong Buy84% buy · 19 analysts
8Strong Buy
8Buy
3Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
May 29, 2026 Wedbush REITERATE Outperform → Outperform
May 6, 2026 HC Wainwright & Co. MAINTAIN Buy → Buy
Mar 17, 2026 Wedbush REITERATE Outperform → Outperform
Feb 18, 2026 Piper Sandler MAINTAIN Overweight → Overweight
Jan 21, 2026 Wedbush REITERATE Outperform → Outperform

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-0.56 ▼ -3.9% $-0.66 — $-0.49 -7% YoY 10
Next Q $-0.57 ▼ -1.4% $-0.70 — $-0.44 -14% YoY 10
Current FY $-2.26 ▼ -5.0% $-2.70 — $-1.96 -7% YoY 10
Next FY $-0.96 ▼ -38.8% $-2.26 — $1.29 58% YoY 9

Top Institutional Holders

FundValueMove
NOMURA ASSET MANAGEMENT CO
FMR LLC$890.0M
BlackRock, Inc.$617.6MADD
VANGUARD PORTFOLIO MANAGEMENT LLC$282.3M
VANGUARD CAPITAL MANAGEMENT LLC$265.4M

Recent Insider Trades

DateInsiderTypeValue
Jun 9, 2026Ros MatthewA$0.00
Jun 9, 2026Harwin PeterA$0.00
Jun 9, 2026Ferrante KarenA$0.00
Jun 9, 2026CAIN CHRISTOPHERA$0.00
May 19, 2026Robbins AndrewG$0.00
50 institutional holders with $4.1B total value (106,834,851 shares) as of 2026-Q1. Top holders: NOMURA, FMR, BlackRock,. Net buying activity: 24 institutions added/increased vs 7 reduced.

Top Institutional Holders — 2026-Q1

#FundSharesValue% of TrackedLast Move
1NOMURA ASSET MANAGEMENT CO LTD$0.000.0%
2FMR LLC23,122,748$890.0M21.6%
3BlackRock, Inc.16,045,014$617.6M15.0%ADD +25.1%
4VANGUARD PORTFOLIO MANAGEMENT LLC7,333,333$282.3M6.9%
5VANGUARD CAPITAL MANAGEMENT LLC6,894,959$265.4M6.5%
6JANUS HENDERSON GROUP PLC5,965,125$229.6M5.6%ADD +31.5%
7STATE STREET CORP5,663,543$218.0M5.3%
8RTW INVESTMENTS, LP5,458,675$210.1M5.1%TRIM -28.1%
9GOLDMAN SACHS GROUP INC4,434,054$170.7M4.2%
10WELLINGTON MANAGEMENT GROUP LLP3,578,622$137.7M3.4%ADD +31.9%
11Invesco Ltd.2,429,629$93.5M2.3%DOUBLED +314.8%
12Holocene Advisors, LP2,250,196$86.6M2.1%ADD +91.0%
13D. E. Shaw & Co., Inc.1,868,389$71.9M1.7%ADD +46.8%
14Pictet Asset Management Holding SA1,798,768$68.8M1.7%DOUBLED +1499.2%
15CITADEL ADVISORS LLC1,714,927$66.0M1.6%
16MARSHALL WACE, LLP1,600,168$61.6M1.5%DOUBLED +158.5%
17Woodline Partners LP1,509,557$58.1M1.4%ADD +84.4%
18Point72 Asset Management, L.P.1,410,826$54.3M1.3%ADD +70.5%
19CHARLES SCHWAB INVESTMENT MANAGEMENT INC1,242,322$47.8M1.2%
20FRED ALGER MANAGEMENT, LLC1,239,700$47.7M1.2%NEW

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
JANUS HENDERSON GROUP PLCADD4,537,4085,965,125+31.5%$229.6M2026-Q1
RTW INVESTMENTS, LPTRIM7,592,2415,458,675-28.1%$210.1M2026-Q1
WELLINGTON MANAGEMENT GROUP LLPADD2,712,3363,578,622+31.9%$137.7M2026-Q1
Invesco Ltd.DOUBLED585,7652,429,629+314.8%$93.5M2026-Q1
Holocene Advisors, LPADD1,178,2082,250,196+91.0%$86.6M2026-Q1
Pictet Asset Management Holding SADOUBLED112,4761,798,768+1499.2%$68.8M2026-Q1
Woodline Partners LPADD818,7821,509,557+84.4%$58.1M2026-Q1
Point72 Asset Management, L.P.ADD827,5251,410,826+70.5%$54.3M2026-Q1
BALYASNY ASSET MANAGEMENT L.P.TRIM1,440,318856,598-40.5%$33.0M2026-Q1
VOYA INVESTMENT MANAGEMENT LLCDOUBLED133,214664,146+398.6%$25.6M2026-Q1
MASSACHUSETTS FINANCIAL SERVICES CO /MA/NEW449,482$17.3M2026-Q1
ExodusPoint Capital Management, LPNEW372,175$14.3M2026-Q1
FEDERATED HERMES, INC.TRIM426,782285,661-33.1%$11.0M2026-Q1
AMERIPRISE FINANCIAL INCADD188,349252,114+33.9%$9.7M2026-Q1
Alyeska Investment Group, L.P.TRIM493,934250,000-49.4%$9.6M2026-Q1
PRUDENTIAL FINANCIAL INCADD120,175178,165+48.3%$6.9M2026-Q1
VICTORY CAPITAL MANAGEMENT INCDOUBLED51,586109,419+112.1%$4.2M2026-Q1
Trexquant Investment LPADD56,106107,443+91.5%$4.1M2026-Q1
ENVESTNET ASSET MANAGEMENT INCDOUBLED15,59562,230+299.0%$2.4M2026-Q1
ADAGE CAPITAL PARTNERS GP, L.L.C.TRIM100,00050,000-50.0%$1.9M2026-Q1
Universal- Beteiligungs- und Servicegesellschaft mbHDOUBLED9,56845,233+372.8%$1.7M2026-Q1
BANK OF MONTREAL /CAN/DOUBLED9,89238,309+287.3%$1.5M2026-Q1
LOS ANGELES CAPITAL MANAGEMENT LLCDOUBLED34329,086+8379.9%$1.1M2026-Q1
STRS OHIOTRIM30,50017,900-41.3%$689.0K2026-Q1
Allspring Global Investments Holdings, LLCADD10,52514,280+35.7%$503.2K2026-Q1
6 unique insiders with 9 transactions. Net insider value: -$242.6M ($0.00 bought, $242.6M sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
Jun 9, 2026Ros MatthewDirectorAWARD17,901
Jun 9, 2026Harwin Peter EvanDirectorAWARD17,901
Jun 9, 2026Ferrante Karen JeanDirectorAWARD17,901
Jun 9, 2026CAIN CHRISTOPHER W.DirectorAWARD17,901
May 19, 2026Robbins Andrew RPresident and CEOGIFT160,000
Apr 1, 2026Ferrante Karen JeanDirectorAWARD686
Mar 31, 2026Fairmount Funds Management LLCDirectorCONVERT7,000,000
Mar 31, 2026Fairmount Funds Management LLCDirectorSELL7,000,000$34.66$242.6M
Mar 31, 2026Fairmount Funds Management LLCDirectorCONVERT28,000
1 SEC filing reports analyzed. Sentiment: 0 bullish, 0 bearish, 0 mixed, 1 neutral. Avg impact: 4.0/10.
Current analyst consensus: Strong Buy (84% buy). Based on 19 analysts: 8 strong buy, 8 buy, 3 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$54.25 mean target +64.0% upside Strong Buy (1.46)
$35.00 Low $72.00 High
MetricValue
Current Price$33.07
Target Low$35.00
Target Mean$54.25
Target Median$55.00
Target High$72.00
# Analysts12
RecommendationStrong Buy (1.46)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-0.56 $-0.66 $-0.49 -6.6% -3.9% 2↑ 4↓ $0.0B 0.0% 10
Next Q
2026-09-30
$-0.57 $-0.70 $-0.44 -13.7% -1.4% 2↑ 4↓ $0.0B 0.0% 10
Current FY
2026-12-31
$-2.26 $-2.70 $-1.96 -6.8% -5.0% 2↑ 7↓ $0.0B 0.0% 10
Next FY
2027-12-31
$-0.96 $-2.26 $1.29 57.6% -38.8% 3↑ 5↓ $0.3B 3549.7% 9

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-0.565
7d ago$-0.567+0.002
30d ago$-0.544-0.021
60d ago$-0.544-0.021
90d ago$-0.557-0.008
4 analyst firms have rated this stock: 0 upgrades, 0 downgrades, 0 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
May 29, 2026 Wedbush REITERATE Outperform Outperform
May 6, 2026 HC Wainwright & Co. MAINTAIN Buy Buy
Mar 17, 2026 Wedbush REITERATE Outperform Outperform
Feb 18, 2026 Piper Sandler MAINTAIN Overweight Overweight
Jan 21, 2026 Wedbush REITERATE Outperform Outperform
Jan 6, 2026 HC Wainwright & Co. MAINTAIN Buy Buy
Dec 19, 2025 JP Morgan MAINTAIN Overweight Overweight

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 20268830084%
May 1, 20268830084%
Apr 1, 20268830084%
Mar 1, 20268830084%
Feb 1, 20268830084%
Jan 1, 20268730083%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

No Reddit sentiment data available yet. Sentiment is analyzed from Reddit investment communities on a rolling basis.

Dec 30, 2026
fda_pdufa
PDUFA: COGT — bezuclastinib in NonAdvanced Systemic Mastocytosis (NonAdvSM) — 2026-12-30
FDA target action date 2026-12-30 for COGT (Cogent Biosciences, Inc.). Drug: bezuclastinib. Indication: NonAdvanced Systemic Mastocytosis (NonAdvSM).
Jun 16, 2026
short_volume
Short Volume: COGT — 71.2% short (0.4M / 0.6M)
Short: 393,511 | Exempt: 1,817 | TRF Vol: 552,687 | Short Ratio: 71.2% | Off-exchange volume (dark pool + OTC)
Jun 12, 2026
fda
Cogent Biosciences Announces Preclinical Data from Novel JAK2 V617F Inhibitor at the 2026 European Hematology Association (EHA) Congress
<p align="center"><em>- </em><em>JAK2 V671F poster presentation showcases potential best-in-class properties, including improved selectivity compared
Jun 12, 2026
fda
Cogent Biosciences Announces Detailed Data from APEX Pivotal Trial of Bezuclastinib in Patients with Advanced Systemic Mastocytosis at the 2026 European Hematology Association (EHA) Congress
<p align="center"><em>-- Bezuclastinib demonstrated rapid and deep clinical benefit in AdvSM patients resulting in an updated objective response rate
Jun 12, 2026
short_volume
Short Volume: COGT — 57.1% short (0.3M / 0.5M)
Short: 287,413 | Exempt: 0 | TRF Vol: 503,700 | Short Ratio: 57.1% | Off-exchange volume (dark pool + OTC)
Jun 11, 2026
short_volume
Short Volume: COGT — 64.1% short (0.3M / 0.5M)
Short: 335,090 | Exempt: 579 | TRF Vol: 522,939 | Short Ratio: 64.1% | Off-exchange volume (dark pool + OTC)
Jun 8, 2026
short_volume
Short Volume: COGT — 71.3% short (0.5M / 0.7M)
Short: 493,051 | Exempt: 0 | TRF Vol: 691,059 | Short Ratio: 71.3% | Off-exchange volume (dark pool + OTC)
Jun 4, 2026
short_volume
Short Volume: COGT — 60.4% short (0.4M / 0.7M)
Short: 416,221 | Exempt: 7,991 | TRF Vol: 689,484 | Short Ratio: 60.4% | Off-exchange volume (dark pool + OTC)
Jun 2, 2026
short_volume
Short Volume: COGT — 71.0% short (1.4M / 1.9M)
Short: 1,352,332 | Exempt: 18,032 | TRF Vol: 1,905,656 | Short Ratio: 71.0% | Off-exchange volume (dark pool + OTC)
Jun 1, 2026
short_volume
Short Volume: COGT — 61.2% short (0.7M / 1.1M)
Short: 654,448 | Exempt: 0 | TRF Vol: 1,069,305 | Short Ratio: 61.2% | Off-exchange volume (dark pool + OTC)
May 30, 2026
fda
Cogent Biosciences Announces Detailed Clinical Data from PEAK Phase 3 Trial with Bezuclastinib in Combination with Sunitinib in Gastrointestinal Stromal Tumors (GIST) at 2026 American Society of Clinical Oncology (ASCO) Annual Meeting
<p align="center"><em>Bezuclastinib combination is first treatment ever to demonstrate statistically significant advantage against active comparator i
May 29, 2026
short_volume
Short Volume: COGT — 73.1% short (0.5M / 0.6M)
Short: 460,399 | Exempt: 130 | TRF Vol: 630,060 | Short Ratio: 73.1% | Off-exchange volume (dark pool + OTC)
May 29, 2026
ftd
FTD: COGT — 20,549 shares ($0.7M) failed to deliver
Settlement: 20260529, Price: $35.38, FTD Value: $727,023.62, COGENT BIOSCIENCES INC COM NEW
May 28, 2026
fda
Cogent Biosciences Announces FDA Acceptance of New Drug Application (NDA) with Priority Review for Bezuclastinib in Combination with Sunitinib for Patients with GIST
<p align="center"><em>NDA acceptance with Priority Review builds upon previous assignment of Breakthrough Therapy Designation and Real-Time Oncology R
May 28, 2026
short_volume
Short Volume: COGT — 62.9% short (0.6M / 1.0M)
Short: 638,590 | Exempt: 700 | TRF Vol: 1,015,839 | Short Ratio: 62.9% | Off-exchange volume (dark pool + OTC)