APGE

Apogee Therapeutics, Inc.

Nasdaq · Biological Products, (No Diagnostic Substances) · CIK 0001974640
$88.33 -1.31% $6.7B
Insider Selling Cluster (2 insiders)High Impact Filing (7/10)19 New Institutional Positions8 Institutional Exits
Vol
Market Cap$6.7B
Cap SizeMid Cap
Analyst ConsensusStrong Buy (80%)
Inst. Holders50 funds
Inst. Value$3.5B
Inst. Activity19 buys / 8 sells
Insider Activity0B / 15S
Insider Net $-$6.6M
SEC Reports11
Press Releases8
Exchange Nasdaq·Sector Biological Products, (No Diagnostic Substances)·CIK 0001974640·Prev Close $89.50

Recent Activity

Jun 10, 2026 Insider
HENDERSON MICHAEL THOMAS sold 6,770 shares
Chief Executive Officer @ $82.21 ($556.6K)
Jun 9, 2026 Insider
Bollinger Lisa was granted 7,657 shares
Director
Jun 9, 2026 Insider
Fox Jennifer A. was granted 7,657 shares
Director
Jun 8, 2026 short_volume
Short Volume: APGE — 76.3% short (0.4M / 0.6M)
Short: 440,568 | Exempt: 0 | TRF Vol: 577,051 | Short Ratio: 76.3% | Off-exchange volume (dark pool
May 27, 2026 SEC
Apogee Therapeutics entered into a revenue participation agreement with Blackstone Life Sciences for up to $1.3 billion
8-K — Impact 7/10
May 27, 2026 SEC
Apogee Therapeutics announced positive 16-week induction dose optimization results from Part B of the Phase 2 APEX trial
8-K — Impact 7/10
May 16, 2026 SEC
CEO Michael Thomas Henderson sold $1.53M worth of APGE stock on May 13, 2026, and CMO Carl Dambkowski sold $311K on May
CLUSTER — Impact 3/10
Inst.
STATE STREET CORP — ADD
2,162,964 shares ($182.1M)

Price Targets

$119.50 +35.3% upside Strong Buy
Current $88.33 Low $81.00 Median $122.50 High $160.00 16 analysts
$81.00 $160.00

Analyst Ratings

Strong Buy80% buy · 25 analysts
10Strong Buy
10Buy
5Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
Jun 8, 2026 RBC Capital MAINTAIN Sector Perform → Sector Perform
May 27, 2026 Truist Securities MAINTAIN Hold → Hold
May 27, 2026 BTIG REITERATE Buy → Buy
May 27, 2026 Wedbush MAINTAIN Outperform → Outperform
May 1, 2026 Rothschild & Co INITIATE Buy

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-0.98 ▲ +12.8% $-1.25 — $0.31 13% YoY 12
Next Q $-1.16 ▲ +2.2% $-1.27 — $-0.93 -4% YoY 12
Current FY $-4.44 ▲ +3.0% $-5.00 — $-3.25 -5% YoY 13
Next FY $-5.19 ▲ +2.1% $-6.96 — $-4.36 -17% YoY 13

Top Institutional Holders

FundValueMove
NOMURA ASSET MANAGEMENT CO
FMR LLC$779.6M
WELLINGTON MANAGEMENT GROUP LLP$368.3M
BlackRock, Inc.$343.9MADD
RTW INVESTMENTS, LP$234.2M

Recent Insider Trades

DateInsiderTypeValue
Jun 10, 2026HENDERSON MICHAELSELL$556.6K
Jun 9, 2026Bollinger LisaA$0.00
Jun 9, 2026Fox JenniferA$0.00
Jun 9, 2026JONES WILLIAMA$0.00
Jun 9, 2026McKenna MarkA$0.00
50 institutional holders with $3.5B total value (41,564,982 shares) as of 2026-Q1. Top holders: NOMURA, FMR, WELLINGTON. Net buying activity: 19 institutions added/increased vs 8 reduced.

Top Institutional Holders — 2026-Q1

#FundSharesValue% of TrackedLast Move
1NOMURA ASSET MANAGEMENT CO LTD$0.000.0%
2FMR LLC9,262,291$779.6M22.3%
3WELLINGTON MANAGEMENT GROUP LLP4,375,703$368.3M10.6%
4BlackRock, Inc.4,085,651$343.9M9.9%ADD +40.9%
5RTW INVESTMENTS, LP2,782,097$234.2M6.7%
6VANGUARD CAPITAL MANAGEMENT LLC2,502,095$210.6M6.0%
7JANUS HENDERSON GROUP PLC2,360,596$198.8M5.7%DOUBLED +324.4%
8STATE STREET CORP2,162,964$182.1M5.2%ADD +28.0%
9DRIEHAUS CAPITAL MANAGEMENT LLC1,920,800$161.7M4.6%
10FRONTIER CAPITAL MANAGEMENT CO LLC1,064,483$89.6M2.6%DOUBLED +121.6%
11BANK OF AMERICA CORP /DE/900,871$75.8M2.2%DOUBLED +101.5%
12ALLIANCEBERNSTEIN L.P.990,297$74.7M2.1%
13GOLDMAN SACHS GROUP INC652,590$54.9M1.6%
14CITADEL ADVISORS LLC598,902$50.4M1.4%
15MORGAN STANLEY595,032$50.1M1.4%TRIM -33.2%
16JENNISON ASSOCIATES LLC585,016$49.2M1.4%NEW
17Polar Capital Holdings Plc539,177$45.4M1.3%
18FEDERATED HERMES, INC.442,738$37.3M1.1%DOUBLED +246.1%
19BALYASNY ASSET MANAGEMENT L.P.438,654$36.9M1.1%NEW
20CHARLES SCHWAB INVESTMENT MANAGEMENT INC420,684$35.4M1.0%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
STATE STREET CORPADD1,690,1862,162,964+28.0%$182.1M2026-Q1
FRONTIER CAPITAL MANAGEMENT CO LLCDOUBLED480,4531,064,483+121.6%$89.6M2026-Q1
MORGAN STANLEYTRIM890,264595,032-33.2%$50.1M2026-Q1
FEDERATED HERMES, INC.DOUBLED127,931442,738+246.1%$37.3M2026-Q1
BALYASNY ASSET MANAGEMENT L.P.NEW438,654$36.9M2026-Q1
LOOMIS SAYLES & CO L PADD255,439362,781+42.0%$30.5M2026-Q1
Capital World InvestorsDOUBLED127,618348,674+173.2%$29.3M2026-Q1
TD ASSET MANAGEMENT INCADD129,290184,792+42.9%$15.6M2026-Q1
MARSHALL WACE, LLPADD50,74480,201+58.1%$6.8M2026-Q1
AMERIPRISE FINANCIAL INCTRIM122,90069,888-43.1%$5.9M2026-Q1
BNP Paribas Asset Management Holding S.A.ADD39,84654,437+36.6%$4.6M2026-Q1
SEI INVESTMENTS CODOUBLED16,32942,203+158.5%$3.6M2026-Q1
FIRST TRUST ADVISORS LPDOUBLED3,41840,776+1093.0%$3.4M2026-Q1
Invesco Ltd.TRIM70,68738,763-45.2%$3.3M2026-Q1
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.ADD20,70934,217+65.2%$2.9M2026-Q1
VOYA INVESTMENT MANAGEMENT LLCADD18,49228,378+53.5%$2.4M2026-Q1
BANQUE PICTET & CIE SATRIM41,80019,960-52.2%$1.7M2026-Q1
GLENMEDE TRUST CO NAADD8,51210,799+26.9%$909.0K2026-Q1
DnB Asset Management ASADD5,7757,991+38.4%$672.6K2026-Q1
STRS OHIOADD3,3004,400+33.3%$370.3K2026-Q1
STIFEL FINANCIAL CORPTRIM5,2142,814-46.0%$236.9K2026-Q1
LMR Partners LLPNEAR_EXIT11,4612,029-82.3%$170.8K2026-Q1
Rockefeller Capital Management L.P.DOUBLED337887+163.2%$74.7K2026-Q1
LOS ANGELES CAPITAL MANAGEMENT LLCTRIM490136-72.2%$11.4K2026-Q1
PNC FINANCIAL SERVICES GROUP, INC.ADD82110+34.1%$9.3K2026-Q1
9 unique insiders with 27 transactions. Net insider value: -$6.6M ($0.00 bought, $6.6M sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
Jun 10, 2026HENDERSON MICHAEL THOMASChief Executive OfficerSELL6,770$82.21$556.6K
Jun 9, 2026Bollinger LisaDirectorAWARD7,657
Jun 9, 2026Fox Jennifer A.DirectorAWARD7,657
Jun 9, 2026JONES WILLIAM A JRDirectorAWARD7,657
Jun 9, 2026McKenna Mark C.DirectorAWARD7,657
Jun 9, 2026Shah Nimish PDirectorAWARD7,657
Jun 9, 2026Fairmount Funds Management LLCDirectorAWARD7,657
Jun 3, 2026Dambkowski CarlChief Medical OfficerSELL5,500$78.71$432.9K
Jun 3, 2026Dambkowski CarlChief Medical OfficerEXERCISE4,125$22.86$94.3K
May 13, 2026HENDERSON MICHAEL THOMASChief Executive OfficerSELL18,659$82.05$1.5M
May 6, 2026Dambkowski CarlChief Medical OfficerSELL3,700$83.92$310.5K
May 6, 2026Dambkowski CarlChief Medical OfficerEXERCISE4,125$22.86$94.3K
May 1, 2026Henderson JaneChief Financial OfficerSELL811$81.02$65.7K
Apr 16, 2026HENDERSON MICHAEL THOMASChief Executive OfficerEXERCISE3,000$22.86$68.6K
Apr 16, 2026Henderson JaneChief Financial OfficerSELL2,000$90.00$180.0K
Apr 8, 2026HENDERSON MICHAEL THOMASChief Executive OfficerSELL17,800$82.48$1.5M
Apr 1, 2026Dambkowski CarlChief Medical OfficerSELL2,698$84.31$227.5K
Apr 1, 2026Dambkowski CarlChief Medical OfficerEXERCISE4,125$22.86$94.3K
Apr 1, 2026Henderson JaneChief Financial OfficerSELL900$84.46$76.0K
Mar 25, 2026Henderson JaneChief Financial OfficerSELL2,000$85.00$170.0K
Mar 11, 2026HENDERSON MICHAEL THOMASChief Executive OfficerSELL8,363$74.29$621.3K
Mar 4, 2026Dambkowski CarlChief Medical OfficerEXERCISE4,125$22.86$94.3K
Mar 2, 2026Henderson JaneChief Financial OfficerSELL300$68.27$20.5K
Feb 11, 2026HENDERSON MICHAEL THOMASChief Executive OfficerSELL11,494$62.96$723.7K
Feb 4, 2026Dambkowski CarlChief Medical OfficerEXERCISE4,125$22.86$94.3K
Feb 4, 2026Dambkowski CarlChief Medical OfficerSELL2,481$64.88$161.0K
Feb 2, 2026Henderson JaneChief Financial OfficerSELL792$65.21$51.6K
11 SEC filing reports analyzed. Sentiment: 4 bullish, 1 bearish, 0 mixed, 6 neutral. Avg impact: 4.7/10.
Current analyst consensus: Strong Buy (80% buy). Based on 25 analysts: 10 strong buy, 10 buy, 5 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$119.50 mean target +35.3% upside Strong Buy (1.44)
$81.00 Low $160.00 High
MetricValue
Current Price$88.33
Target Low$81.00
Target Mean$119.50
Target Median$122.50
Target High$160.00
# Analysts16
RecommendationStrong Buy (1.44)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-0.98 $-1.25 $0.31 13.5% +12.8% 12↑ 0↓ $0.0B 0.0% 12
Next Q
2026-09-30
$-1.16 $-1.27 $-0.93 -4.3% +2.2% 10↑ 2↓ $0.0B 0.0% 12
Current FY
2026-12-31
$-4.44 $-5.00 $-3.25 -5.2% +3.0% 12↑ 1↓ $0.0B 0.0% 13
Next FY
2027-12-31
$-5.19 $-6.96 $-4.36 -17.0% +2.1% 10↑ 4↓ $0.0B 39.3% 13

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-0.978
7d ago$-0.886-0.091
30d ago$-1.121+0.143
60d ago$-1.182+0.205
90d ago$-1.194+0.217
11 analyst firms have rated this stock: 0 upgrades, 1 downgrades, 4 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
Jun 8, 2026 RBC Capital MAINTAIN Sector Perform Sector Perform
May 27, 2026 Truist Securities MAINTAIN Hold Hold
May 27, 2026 BTIG REITERATE Buy Buy
May 27, 2026 Wedbush MAINTAIN Outperform Outperform
May 1, 2026 Rothschild & Co INITIATE Buy
Mar 30, 2026 Mizuho MAINTAIN Outperform Outperform
Mar 24, 2026 Citigroup MAINTAIN Buy Buy
Mar 24, 2026 Canaccord Genuity MAINTAIN Buy Buy
Mar 24, 2026 Guggenheim MAINTAIN Buy Buy
Mar 23, 2026 BTIG REITERATE Buy Buy
Mar 18, 2026 Truist Securities INITIATE Hold
Mar 16, 2026 BTIG REITERATE Buy Buy
Mar 3, 2026 RBC Capital MAINTAIN Sector Perform Sector Perform
Mar 3, 2026 Wedbush MAINTAIN Outperform Outperform
Jan 22, 2026 RBC Capital DOWNGRADE Outperform Sector Perform
Jan 7, 2026 Wolfe Research INITIATE Peer Perform
Jan 6, 2026 BTIG MAINTAIN Buy Buy
Jan 5, 2026 BTIG MAINTAIN Buy Buy
Dec 17, 2025 Stephens & Co. INITIATE Overweight

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 2026101050080%
May 1, 202610940083%
Apr 1, 202610940083%
Mar 1, 202610930086%
Feb 1, 202610930086%
Jan 1, 202610910095%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

No Reddit sentiment data available yet. Sentiment is analyzed from Reddit investment communities on a rolling basis.

Jun 8, 2026
short_volume
Short Volume: APGE — 76.3% short (0.4M / 0.6M)
Short: 440,568 | Exempt: 0 | TRF Vol: 577,051 | Short Ratio: 76.3% | Off-exchange volume (dark pool + OTC)
Jun 5, 2026
short_volume
Short Volume: APGE — 80.8% short (0.4M / 0.5M)
Short: 437,293 | Exempt: 244 | TRF Vol: 541,194 | Short Ratio: 80.8% | Off-exchange volume (dark pool + OTC)
Jun 4, 2026
short_volume
Short Volume: APGE — 71.4% short (0.4M / 0.6M)
Short: 404,933 | Exempt: 3,404 | TRF Vol: 566,812 | Short Ratio: 71.4% | Off-exchange volume (dark pool + OTC)
May 29, 2026
short_volume
Short Volume: APGE — 80.6% short (0.4M / 0.5M)
Short: 413,260 | Exempt: 2,388 | TRF Vol: 512,669 | Short Ratio: 80.6% | Off-exchange volume (dark pool + OTC)
May 28, 2026
other
Apogee Therapeutics to Participate in Upcoming June Conferences
<p align="justify">SAN FRANCISCO and BOSTON, May 28, 2026 (GLOBE NEWSWIRE) -- Apogee Therapeutics, Inc. (Nasdaq: APGE), today announced that members
May 28, 2026
short_volume
Short Volume: APGE — 66.1% short (0.4M / 0.6M)
Short: 427,487 | Exempt: 0 | TRF Vol: 646,966 | Short Ratio: 66.1% | Off-exchange volume (dark pool + OTC)
May 27, 2026
contract
Apogee Therapeutics Announces $1.3 Billion Strategic Financing Collaboration with Blackstone Life Sciences to Advance Phase 3 Development and Commercialization of Zumilokibart
<p align="center"><em>Up to $1.3 billion in flexible, non-dilutive capital, including up to $800 million of synthetic royalty and access of up to $500
May 27, 2026
fda
Apogee Therapeutics Announces Positive 16-Week Part B Induction Dose Optimization Results from Phase 2 APEX Trial of Zumilokibart in Moderate-to-Severe Atopic Dermatitis
<p align="center"><em>APEX Part B met all primary and secondary endpoints with high statistical significance; mid-dose zumilokibart planned to advance
May 27, 2026
short_volume
Short Volume: APGE — 57.2% short (1.3M / 2.2M)
Short: 1,280,002 | Exempt: 0 | TRF Vol: 2,239,120 | Short Ratio: 57.2% | Off-exchange volume (dark pool + OTC)
May 26, 2026
fda
Apogee Therapeutics to Host Conference Call to Report Part B 16-Week Data from the Phase 2 APEX Trial of Zumilokibart in Patients with Moderate-to-Severe Atopic Dermatitis on May 27, 2026
Webcast to be held Wednesday, May 27th at 8:00 a.m. ET <pre>Webcast to be held Wednesday, May 27th at 8:00 a.m. ET</pre>
May 11, 2026
earnings
Apogee Therapeutics Provides Pipeline Progress and Reports First Quarter 2026 Financial Results
<p align="center"><em>Zumilokibart advancing across multiple indications, with Phase 3 initiation in atopic dermatitis (AD) expected later this year:<
May 11, 2026
earnings_calendar
APGE Q1 2026 Earnings Scheduled — 2026-05-11
Apr 30, 2026
short_interest
FTD: APGE — 10,332 shares ($0.8M) failed to deliver
Settlement: 20260430, Price: $82.03, FTD Value: $847,533.96, APOGEE THERAPEUTICS INC COM
Apr 20, 2026
short_interest
FTD: APGE — 6,094 shares ($0.6M) failed to deliver
Settlement: 20260420, Price: $92.20, FTD Value: $561,866.8, APOGEE THERAPEUTICS INC COM
Apr 17, 2026
short_interest
FTD: APGE — 59,996 shares ($5.4M) failed to deliver
Settlement: 20260417, Price: $90.55, FTD Value: $5,432,637.8, APOGEE THERAPEUTICS INC COM