ANVS

Annovis Bio, Inc.

NYSE · Pharmaceutical Preparations · Inc. DE · CIK 0001477845
$1.79 -5.29% $61.3M
High Impact Filing (7/10)5 New Institutional Positions
Vol
Market Cap$61.3M
Cap SizeMicro Cap
Analyst ConsensusStrong Buy (88%)
Inst. Holders5 funds
Inst. Value$5.2M
Inst. Activity5 buys / 0 sells
Insider Activity2B / 0S
Insider Net $$1.5M
Reddit Sentiment57° Neutral
SEC Reports5
Press Releases2
Exchange NYSE·Sector Pharmaceutical Preparations·Inc. DE·CIK 0001477845·Prev Close $1.89

Recent Activity

Jun 5, 2026 short_volume
Short Volume: ANVS — 56.7% short (0.4M / 0.8M)
Short: 441,334 | Exempt: 3,800 | TRF Vol: 777,887 | Short Ratio: 56.7% | Off-exchange volume (dark p
May 20, 2026 SEC
Annovis Bio is raising approximately $13.8M in net proceeds through a dilutive offering of 7.9M shares and warrants, pri
424B5 — Impact 6/10
May 20, 2026 Insider
Hoffman Michael B bought 2,562 shares
Director @ $1.75 ($4.5K)
May 19, 2026 SEC
Annovis Bio filed a preliminary 424B5 for an underwritten offering of common stock and warrants, with no final pricing d
424B5 — Impact 7/10
May 15, 2026 SEC
Annovis Bio reported Q1 2026 results showing increased net loss per share ($0.63 vs $0.32) and cash burn, but highlighte
8-K — Impact 5/10
Apr 2, 2026 Insider
Hoffman Michael B bought 713,800 shares
Director @ $2.10 ($1.5M)
Inst.
VANGUARD GROUP INC — ADD
923,201 shares ($3.2M)
Inst.
TWO SIGMA INVESTMENTS, LP — NEW
551,837 shares ($1.9M)

Price Targets

$12.50 +606.2% upside Strong Buy
Current $1.77 Low $8.00 Median $12.50 High $17.00 2 analysts
$8.00 $17.00

Analyst Ratings

Strong Buy88% buy · 8 analysts
2Strong Buy
5Buy
1Hold
0Sell
0Strong Sell
Recent Analyst Actions
DateFirmActionRating
Apr 14, 2026 Canaccord Genuity MAINTAIN Buy → Buy

Earnings Estimates

PeriodEPS Est.RangeGrowth#
Current Q $-0.48 ▼ -65.5% $-0.48 — $-0.48 -50% YoY 1
Next Q $-0.44 ▼ -57.1% $-0.44 — $-0.44 -19% YoY 1
Current FY $-1.80 ▼ -57.9% $-1.80 — $-1.80 -29% YoY 1
Next FY $-1.16 ▲ +14.7% $-1.16 — $-1.16 36% YoY 1

Top Institutional Holders

FundValueMove
VANGUARD GROUP INC$3.2MADD
TWO SIGMA INVESTMENTS, LP$1.9MNEW
WELLS FARGO & COMPANY/MN$49.5KADD
MORGAN STANLEY$34.3KADD
BANK OF AMERICA CORP$716.00ADD

Recent Insider Trades

DateInsiderTypeValue
May 20, 2026Hoffman MichaelBUY$4.5K
Apr 2, 2026Hoffman MichaelBUY$1.5M

Reddit Sentiment

57°
Neutral
Bearish Neutral Bullish
3 mentions 1 bullish 0 bearish
5 institutional holders with $5.2M total value (1,499,453 shares) as of 2025-Q4. Top holders: VANGUARD, TWO, WELLS. Net buying activity: 5 institutions added/increased vs 0 reduced.

Top Institutional Holders — 2025-Q4

#FundSharesValue% of TrackedLast Move
1VANGUARD GROUP INC923,201$3.2M61.6%ADD +25.1%
2TWO SIGMA INVESTMENTS, LP551,837$1.9M36.8%NEW
3WELLS FARGO & COMPANY/MN14,307$49.5K1.0%ADD +46.8%
4MORGAN STANLEY9,901$34.3K0.7%ADD +34.0%
5BANK OF AMERICA CORP /DE/207$716.000.0%ADD +42.8%

Recent Position Changes

FundActionPrev SharesCurr SharesChange %ValueQuarter
VANGUARD GROUP INCADD738,003923,201+25.1%$3.2M2025-Q4
TWO SIGMA INVESTMENTS, LPNEW551,837$1.9M2025-Q4
WELLS FARGO & COMPANY/MNADD9,74614,307+46.8%$49.5K2025-Q4
MORGAN STANLEYADD7,3899,901+34.0%$34.3K2025-Q4
BANK OF AMERICA CORP /DE/ADD145207+42.8%$716.002025-Q4
MORGAN STANLEYTRIM12,1947,389-39.4%$15.3K2025-Q3
UBS Group AGNEAR_EXIT26,317633-97.6%$1.3K2025-Q3
UBS Group AGNEAR_EXIT160,87626,317-83.6%$57.1K2025-Q2
TWO SIGMA INVESTMENTS, LPEXIT166,2190-100.0%$0.002025-Q2
RENAISSANCE TECHNOLOGIES LLCEXIT21,8000-100.0%$0.002025-Q2
VANGUARD GROUP INCADD466,277647,920+39.0%$971.9K2025-Q1
TWO SIGMA INVESTMENTS, LPDOUBLED10,923166,219+1421.7%$249.3K2025-Q1
UBS Group AGDOUBLED48,736160,876+230.1%$241.3K2025-Q1
CITADEL ADVISORS LLCNEAR_EXIT535,707125,300-76.6%$187.9K2025-Q1
RENAISSANCE TECHNOLOGIES LLCNEW21,800$32.7K2025-Q1
MORGAN STANLEYDOUBLED1,30010,189+683.8%$15.3K2025-Q1
CITADEL ADVISORS LLCADD385,092535,707+39.1%$2.7M2024-Q4
UBS Group AGDOUBLED1,84748,736+2538.7%$245.1K2024-Q4
MORGAN STANLEYNEAR_EXIT5,4981,350-75.4%$10.9K2024-Q3
1 unique insiders with 2 transactions. Net insider value: $1.5M ($1.5M bought, $0.00 sold).

Insider Transactions

DateInsiderTitleTypeSharesPriceValue
May 20, 2026Hoffman Michael BDirectorBUY2,562$1.75$4.5K
Apr 2, 2026Hoffman Michael BDirectorBUY713,800$2.10$1.5M
Current analyst consensus: Strong Buy (88% buy). Based on 8 analysts: 2 strong buy, 5 buy, 1 hold, 0 sell, 0 strong sell.

Analyst Price Targets

$12.50 mean target +606.2% upside Strong Buy (1.50)
$8.00 Low $17.00 High
MetricValue
Current Price$1.77
Target Low$8.00
Target Mean$12.50
Target Median$12.50
Target High$17.00
# Analysts2
RecommendationStrong Buy (1.50)

Earnings Estimates & Revisions

PeriodEPS AvgEPS LowEPS HighEPS Growth30d Rev.Up/DownRev. AvgRev. GrowthAnalysts
Current Q
2026-06-30
$-0.48 $-0.48 $-0.48 -50.0% -65.5% 0↑ 1↓ $0.0B 0.0% 1
Next Q
2026-09-30
$-0.44 $-0.44 $-0.44 -18.9% -57.1% 0↑ 1↓ $0.0B 0.0% 1
Current FY
2026-12-31
$-1.80 $-1.80 $-1.80 -28.6% -57.9% 0↑ 1↓ $0.0B 0.0% 1
Next FY
2027-12-31
$-1.16 $-1.16 $-1.16 35.6% +14.7% 1↑ 0↓ $0.0B 0.0% 1

Current Quarter EPS Revision History

TimepointEPS EstimateChange
Current$-0.480
7d ago$-0.290-0.190
30d ago$-0.290-0.190
60d ago$-0.310-0.170
90d ago$-0.280-0.200
1 analyst firms have rated this stock: 0 upgrades, 0 downgrades, 0 initiations.

Individual Analyst Actions

DateAnalyst FirmActionPrevious RatingNew Rating
Apr 14, 2026 Canaccord Genuity MAINTAIN Buy Buy

Monthly Consensus History

PeriodStrong BuyBuyHoldSellStrong SellBuy %Distribution
Jun 1, 20262510088%
May 1, 20262710090%
Apr 1, 20262710090%
Mar 1, 20262710090%
Feb 1, 20262710090%
Jan 1, 20262710090%
Strong BuyBuyHoldSellStrong Sell

No congressional trading data available for this ticker. Data is sourced from Senate and House financial disclosure filings.

57°
Neutral
Bearish Neutral Bullish
3 mentions 1 bullish 0 bearish 2 time periods

Reddit Sentiment History

DateMentionsSentimentBullishBearishThreads
May 6, 2026258° Warm102
May 6, 2026144° Neutral001
Jun 5, 2026
short_volume
Short Volume: ANVS — 56.7% short (0.4M / 0.8M)
Short: 441,334 | Exempt: 3,800 | TRF Vol: 777,887 | Short Ratio: 56.7% | Off-exchange volume (dark pool + OTC)
Jun 4, 2026
short_volume
Short Volume: ANVS — 66.4% short (0.7M / 1.1M)
Short: 737,392 | Exempt: 4,485 | TRF Vol: 1,111,145 | Short Ratio: 66.4% | Off-exchange volume (dark pool + OTC)
Jun 2, 2026
short_volume
Short Volume: ANVS — 69.0% short (0.5M / 0.8M)
Short: 524,007 | Exempt: 915 | TRF Vol: 759,795 | Short Ratio: 69.0% | Off-exchange volume (dark pool + OTC)
May 21, 2026
short_volume
Short Volume: ANVS — 55.4% short (0.3M / 0.6M)
Short: 306,113 | Exempt: 1,112 | TRF Vol: 552,484 | Short Ratio: 55.4% | Off-exchange volume (dark pool + OTC)
May 19, 2026
offering
Annovis Announces Launch of Proposed Public Offering of Common Stock and Accompanying Warrants
<p>MALVERN, Pa., May 19, 2026 (GLOBE NEWSWIRE) -- Annovis Bio, Inc. (NYSE: ANVS) (“Annovis” or the “Company”), a Phase 3 clinical-stage biotechnolog
May 15, 2026
earnings
Annovis Provides Corporate Updates and Reports First Quarter 2026 Financial Results
<p>MALVERN, Pa., May 15, 2026 (GLOBE NEWSWIRE) -- Annovis Bio, Inc. (NYSE: ANVS) (“Annovis” or the “Company”), a Phase 3 clinical-stage biotechnolog
May 13, 2026
earnings_calendar
ANVS Q1 2026 Earnings Scheduled — 2026-05-13
May 11, 2026
earnings_calendar
ANVS Q1 2026 Earnings Scheduled — 2026-05-11
Apr 23, 2026
short_volume
Short Volume: ANVS — 65.4% short (0.4M / 0.6M)
Short: 422,868 | Exempt: 440 | TRF Vol: 646,953 | Short Ratio: 65.4% | Off-exchange volume (dark pool + OTC)
Apr 20, 2026
short_volume
Short Volume: ANVS — 63.9% short (0.4M / 0.6M)
Short: 413,916 | Exempt: 1,150 | TRF Vol: 647,769 | Short Ratio: 63.9% | Off-exchange volume (dark pool + OTC)
Apr 17, 2026
short_volume
Short Volume: ANVS — 61.5% short (0.4M / 0.7M)
Short: 445,994 | Exempt: 8,623 | TRF Vol: 725,097 | Short Ratio: 61.5% | Off-exchange volume (dark pool + OTC)
Apr 15, 2026
short_volume
Short Volume: ANVS — 71.1% short (0.4M / 0.6M)
Short: 424,807 | Exempt: 657 | TRF Vol: 597,647 | Short Ratio: 71.1% | Off-exchange volume (dark pool + OTC)
Apr 14, 2026
short_volume
Short Volume: ANVS — 68.8% short (0.6M / 0.8M)
Short: 579,065 | Exempt: 9,591 | TRF Vol: 841,460 | Short Ratio: 68.8% | Off-exchange volume (dark pool + OTC)
Apr 13, 2026
short_volume
Short Volume: ANVS — 75.1% short (1.0M / 1.4M)
Short: 1,027,608 | Exempt: 4,159 | TRF Vol: 1,367,811 | Short Ratio: 75.1% | Off-exchange volume (dark pool + OTC)
Apr 10, 2026
earnings
Annovis Closes $10 Million Offering, Extending Cash Runway Through Phase 3 Alzheimer's Disease 6-Month NDA Submission
<p>MALVERN, Pa., April 10, 2026 (GLOBE NEWSWIRE) -- Annovis Bio, Inc. (NYSE: ANVS) (“Annovis” or the “Company”), a Phase 3 clinical-stage biotechnol