TTRX Turn Therapeutics Inc.
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Executive Summary
Turn Therapeutics announced a peer-reviewed publication in the Journal of Dermatological Treatment showing that GX-03 achieved a statistically significant reduction in disease severity in a murine dermatitis model characterized by IL-36 expression. This is the first in a planned series of publications supporting the scientific rationale for GX-03, which is currently in Phase 2 evaluation for moderate-to-severe atopic dermatitis with topline results expected in mid-2026.
Actionable Insight
The publication provides incremental scientific validation for GX-03's mechanism but does not change the binary Phase 2 readout expected mid-2026. Monitor for the subsequent mechanistic manuscript and the Phase 2 topline results as the next major catalysts.
Key Facts
- GX-03 achieved mean IGA score of 1.44 vs 3.00 in controls (p=0.0003) in murine IL-36 model
- No treatment-related adverse effects observed
- First in a planned series of peer-reviewed publications on GX-03
- GX-03 currently in Phase 2 RCT for moderate-to-severe atopic dermatitis; topline results expected mid-2026
- Subsequent manuscript already in review characterizing mechanistic implications
Financial Impact
No financial data provided; pre-revenue clinical-stage biotech with $171M market cap
Risk Factors
- Preclinical murine data may not translate to human clinical outcomes
- Phase 2 topline results are the true catalyst; publication alone does not de-risk the program
- Clinical-stage biotech with no approved products or revenue
Market Snapshot
Documents Analyzed
This report is based on 5 SEC documents filed with EDGAR.
| Document | Accession Number |
|---|---|
| 8-K Filing (Primary) | 0001213900-26-061244 |
| Document: ea029186601ex99-1.htm | 0001213900-26-061244 |
| Document: 0001213900-26-061244-index-headers.html | 0001213900-26-061244 |
| Document: 0001213900-26-061244-index.html | 0001213900-26-061244 |
| Document: 0001213900-26-061244.txt | 0001213900-26-061244 |
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Jun 3, 2026
9d ago
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8-K
| $6.02 $5.75 | ▼ −4.57% | ▼ −4.97% | $6.05 (+0.42%) |
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Jun 1, 2026
11d ago
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8-K
| $6.33 $6.42 | ▲ +1.42% | ▲ +1.28% | $6.05 (−4.50%) |
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May 27, 2026
16d ago
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8-K
| $5.29 $5.31 | ▲ +0.38% | ▼ −0.17% | $6.05 (+14.27%) |
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May 19, 2026
24d ago
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| $4.55 $4.76 | ▲ +4.62% | ▲ +3.58% | $6.05 (+32.86%) |
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May 18, 2026
25d ago
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8-K
| $4.90 $4.55 | ▼ −7.14% | ▼ −6.49% | $6.05 (+23.37%) |
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May 11, 2026
4w ago
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8-K
| $3.98 $3.98 | · 0.00% | ▼ −0.54% | $6.05 (+51.88%) |
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Apr 3, 2026
10w ago
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EFFECT
| $3.33 $3.36 | ▼ −0.90% | ▼ −0.84% | $6.05 (−81.53%) |
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Mar 31, 2026
10w ago
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8-K
| $3.12 $3.35 | ▲ +7.54% | ▲ +7.46% | $6.05 (+94.06%) |
US Market Status
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