TPST Tempest Therapeutics, Inc.

BEARISH Impact: 5/10 8-K
Horizon weeks Filed May 22, 2026 Processed 21d 16h ago SEC 0001193125-26-237150
8-K context-dependent: Items 5.02
Latest settled — T+5d ⚠ clustered
TPST ▼ -25.99% at T+5d
SHORT call ✓ call won +25.99% · α vs SPY +27.20% · entry $1.77 → $1.31
Next anchor: T+20d in 10d
Currently $1.26 · +28.81% from $1.77 entry (call sign-flipped)
Entry anchored
May 22, 2026
via day open
T+1d
+1.13%
call -1.13% · α -1.12%
$1.79
settled 18d ago
T+5d
-25.99%
call +25.99% · α +27.20%
$1.31
settled 12d ago
T+20d
call — · α —
in 10d
T+60d
call — · α —
in 2mo

Price Chart

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Executive Summary

Three board directors (Stephen Brady, Michael Raab, Christine Pellizzari) resigned from Tempest Therapeutics' board effective May 22, 2026. The company states these resignations were not due to any disagreement with operations or policies. No replacements were named, and departing directors waived accrued retainer fees under separation agreements while retaining existing stock options and indemnification rights. For a micro-cap biotech ($27M market cap), the simultaneous departure of a quarter-plus of the board is a governance red flag.

Actionable Insight

Simultaneous departure of three directors without named replacements at a micro-cap biotech suggests potential board instability or a strategic pivot. Monitor for any subsequent 8-Ks naming new directors, filings on Nasdaq listing compliance (as board size may fall below minimum requirements), and the upcoming 10-Q for the quarter ending June 30, 2026, which should include the separation agreements as exhibits. Historical calibration shows prior TPST short-side reports have had negative T+20 alpha — this governance concern is a new negative catalyst for the stock.

Key Facts

  • Three directors resigned simultaneously: Stephen Brady, Michael Raab, and Christine Pellizzari
  • Resignations effective May 22, 2026
  • No replacements have been named
  • Company states no disagreement with operations, policies, or practices
  • Directors waived all accrued/unpaid retainer fees under separation agreements
  • Outstanding stock options and share ownership rights unaffected; indemnification agreements remain for six years
  • President and CEO Matthew Angel remains as sole C-suite signatory
  • Market cap: $27M (Nasdaq-listed micro-cap biotech)

Financial Impact

No direct financial figures in filing; retainer fee waiver is trivial for a $27M company

governanceboard composition

Risk Factors

  • Nasdaq may require a minimum board size; three departures simultaneously could risk non-compliance
  • No replacements named suggests difficulty attracting qualified directors or pending corporate action
  • Potential loss of institutional confidence in governance for a development-stage biotech reliant on partnerships and financing
  • Waiver of fees could signal cash constraints at the company

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
86% bullish (7 analysts)

Documents Analyzed

This report is based on 4 SEC documents filed with EDGAR.

DocumentAccession Number
8-K Filing (Primary)0001193125-26-237150
Document: 0001193125-26-237150-index-headers.html0001193125-26-237150
Document: 0001193125-26-237150-index.html0001193125-26-237150
Document: 0001193125-26-237150.txt0001193125-26-237150
11 reports for TPST
Performance horizon
83% Hit rate 5 of 6 directional calls best @ T+5▲ +25.99%May 22, 2026
Filters
Rows
Reports for TPST — sortable, filterable
Type Now
May 29, 2026
14d ago
8-K
NEUTRAL ★ 2/10
$1.45 $1.27▼ −12.41%▼ −9.66%$1.26 (−13.10%)
May 29, 2026
15d ago
Press Release
BEARISH ★ 6/10
$1.53 $1.27▲ +16.99%▲ +16.70%$1.26 (+17.65%)
May 22, 2026
21d ago
8-K
BEARISH ★ 8/10
$1.77 $1.31▲ +25.99%▲ +27.20%$1.26 (+28.81%)
May 22, 2026
21d ago
8-K
BEARISH ★ 5/10
$1.77 $1.31▲ +25.99%▲ +27.20%$1.26 (+28.81%)
May 14, 2026
29d ago
8-K
BEARISH ★ 7/10
$1.83 $1.86▼ −1.64%▼ −0.68%$1.26 (+31.15%)
Apr 29, 2026
6w ago
Press Release
BULLISH ★ 5/10
$1.74 $2.15▲ +23.56%▲ +20.45%$1.26 (−27.59%)
Apr 6, 2026
9w ago
EFFECT
NEUTRAL ★ 4/10
$1.59 $2.14▲ +34.59%▲ +30.46%$1.26 (−20.75%)
Apr 2, 2026
10w ago
S-3
NEUTRAL ★ 4/10
$1.59 $2.05▲ +28.93%▲ +25.31%$1.26 (−20.75%)
Mar 30, 2026
10w ago
Press Release
MIXED ★ 6/10
$1.52 $1.56▲ +2.63%▼ −1.67%$1.26 (−17.11%)
Mar 11, 2026
13w ago
Press Release
BULLISH ★ 7/10
$2.40 $2.16▼ −10.00%▼ −7.81%$1.26 (−47.50%)
Showing 10 of 11

US Market Status

Market Closed — Opens Mon (47h 35m)

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