SLNCF Silence Therapeutics plc
Price Chart
Executive Summary
Silence Therapeutics reported Q1 2026 revenue of $0.4M vs consensus $1.5M, a significant miss reflecting early-stage biotech volatility. Net loss narrowed to $15.0M ($0.11 per share) from $28.5M YoY, driven by lower R&D spend. The key catalyst remains Phase 2 SANRECO topline in August 2026.
Actionable Insight
The stock will trade on SANRECO Phase 2 readout in August 2026, not Q1 financials. Monitor abstract presentations at EHA (June) and EAS (May) for additional pipeline signals.
Key Facts
- Q1 2026 revenue $0.4M; consensus was $1.5M (miss)
- Net loss $15.0M vs $28.5M YoY, improvement due to lower R&D expenses
- Cash & investments $70.1M as of March 31, 2026
- Phase 2 SANRECO trial (divesiran) on track for topline results in August 2026
- SLN312 Phase 1 abstract accepted for late-breaking oral at EAS Congress
Financial Impact
Revenue miss of $1.1M (73% below consensus) but pre-revenue biotech; cash burn manageable
Risk Factors
- Phase 2 SANRECO trial failure or delay
- Cash runway only ~12 quarters at current burn rate without additional partnering or financing
Market Snapshot
Documents Analyzed
This report is based on 6 SEC documents filed with EDGAR.
| Document | Accession Number |
|---|---|
| 8-K Filing (Primary) | 0001193125-26-210428 |
| Document: sln-20260507.htm | 0001193125-26-210428 |
| Document: 0001193125-26-210428-index-headers.html | 0001193125-26-210428 |
| Document: 0001193125-26-210428-index.html | 0001193125-26-210428 |
| Document: 0001193125-26-210428.txt | 0001193125-26-210428 |
| 8-K Data (Synthetic) | 0001193125-26-210428 |
Filters
| Type | Now | ||||
|---|---|---|---|---|---|
|
May 28, 2026
16d ago
|
EFFECT
| $1.06 $1.06 | · 0.00% | ▲ +0.32% | $1.06 (+0.00%) |
|
May 27, 2026
16d ago
|
424B5
| $1.06 $1.06 | · 0.00% | ▲ +0.32% | $1.06 (+0.00%) |
|
May 18, 2026
25d ago
|
S-3
| $1.45 $1.06 | ▲ +27.02% | ▲ +29.32% | $1.06 (+27.02%) |
|
May 7, 2026
5w ago
|
8-K
| $2.63 $1.45 | ▼ −44.77% | ▼ −46.28% | $1.06 (−59.70%) |
US Market Status
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