PEPG PepGen Inc.
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Executive Summary
PepGen reported Q1 2026 net loss of $17.8M ($-0.26/share), narrower than the $30.2M loss in Q1 2025, with cash of $132.3M sufficient into 2H 2027. The FREEDOM2-DM1 5 mg/kg cohort showed favorable safety and efficacy data, the 10 mg/kg cohort is fully enrolled with data expected in 2H 2026, but an FDA partial clinical hold remains unresolved.
Actionable Insight
The stock will trade on FREEDOM2 10 mg/kg data in 2H 2026 and resolution of the FDA partial clinical hold. Near-term catalyst is limited — monitor for FDA feedback and any preclinical study updates. The improved cash position reduces near-term dilution risk.
Key Facts
- Net loss of $17.8M ($-0.26/share) for Q1 2026 vs $30.2M ($-0.92/share) in Q1 2025
- Cash, cash equivalents and marketable securities of $132.3M as of March 31, 2026
- FREEDOM2-DM1 5 mg/kg cohort demonstrated favorable safety, splicing and vHOT data
- FREEDOM2 10 mg/kg cohort fully enrolled, data on track for 2H 2026
- FDA partial clinical hold on FREEDOM2 study remains unresolved
- 13 patients enrolled in open label extension at 5 mg/kg with no discontinuations
Financial Impact
Net loss improved by $12.4M YoY to $17.8M; cash burn of $16.2M in Q1 2026
Risk Factors
- FDA partial clinical hold could delay or derail FREEDOM2 trial if not resolved
- 10 mg/kg cohort data may not replicate 5 mg/kg safety/efficacy profile
- Pre-revenue biotech with no approved products — binary clinical risk
- Cash runway only into 2H 2027 — potential future dilution
Market Snapshot
Documents Analyzed
This report is based on 6 SEC documents filed with EDGAR.
| Document | Accession Number |
|---|---|
| 8-K Filing (Primary) | 0001193125-26-219424 |
| Document: pepg-20260512.htm | 0001193125-26-219424 |
| Document: 0001193125-26-219424-index-headers.html | 0001193125-26-219424 |
| Document: 0001193125-26-219424-index.html | 0001193125-26-219424 |
| Document: 0001193125-26-219424.txt | 0001193125-26-219424 |
| 8-K Data (Synthetic) | 0001193125-26-219424 |
Track record builds as more directional reports settle.
Filters
| Type | Now | ||||
|---|---|---|---|---|---|
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May 22, 2026
18d ago
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EFFECT
| $1.51 $1.47 | ▲ +2.65% | ▲ +4.31% | $1.38 (+8.61%) |
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May 19, 2026
21d ago
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S-3
| $1.38 $1.52 | ▼ −10.14% | ▼ −7.90% | $1.38 (+0.00%) |
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May 12, 2026
28d ago
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8-K
| $1.78 $1.38 | ▼ −22.47% | ▼ −21.31% | $1.38 (−22.47%) |
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Mar 4, 2026
13w ago
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8-K
| $5.51 $6.15 | ▲ +11.72% | ▲ +13.95% | $1.38 (−74.93%) |
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Mar 4, 2026
14w ago
|
Insider Cluster
| $6.76 $6.29 | ▼ −6.95% | ▼ −5.62% | $1.38 (−79.59%) |
US Market Status
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