KRYS Krystal Biotech, Inc.

BULLISH Impact: 4/10 ANALYST-UPGRADE
Processed 1mo ago SEC analyst-KRYS-citigrou-20260106
5 firms acted on KRYS: Wolfe Research, Citigroup, Clear Street, Jefferies, Citigroup
Latest settled — T+20d
KRYS ▲ +15.35% at T+20d
LONG call ✓ call won +15.35% · α vs SPY +9.98% · entry $274.21 → $316.30
Next anchor: T+60d in 5w
Last close $301.00 (close Jun 5) · +9.77% from $274.21 entry
Entry anchored
Apr 16, 03:59 PM ET
via Databento tick
T+1d
+0.84%
call +0.84% · α +1.03%
$276.50
settled 7w ago
T+5d
-0.62%
call -0.62% · α -1.17%
$272.52
settled 6w ago
T+20d
+15.35%
call +15.35% · α +9.98%
$316.30
settled 24d ago
T+60d
call — · α —
in 5w

Price Chart

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Executive Summary

Citigroup upgraded KRYS from Neutral to Buy with a $309 price target, implying 18% upside, marking a rare upgrade in a cluster of recent maintains and initiations. The firm has a 57% accuracy rate on 7 scored calls, above its peer average, though below top-tier performers like B of A Securities (100% on 2). Consensus stands at 9 analysts with a mean target of $314 and median of $310, making Citigroup’s PT slightly below median but above the current $260.95 share price. Momentum is neutral: 1 upgrade, no downgrades in the past 30 days. EPS estimates have declined slightly over the past month across all horizons, with 1 upward and 1 downward revision in the last 30 days for current-year EPS. Insider selling totaled over $2.9M in the past month, including material sales by executives Krishnan S., Krishnan S., and Daniel Janney. However, institutional inflows were strong, led by Norges Bank ($70.2M new) and UBS (+86.5%, $49.2M). Despite insider selling, the upgrade from a moderately accurate firm aligns with institutional accumulation, suggesting divergent sentiment between insiders and large funds.

Impact Score

Base Score
3/7
LLM Adjustment
+1
Final Score
4/10

Recent Analyst Activity

DateFirmActionRatingPrice Target
2026-03-27 Wolfe Research initiate Peer Perform
2026-02-25 Guggenheim maintain Buy $284.00
2026-02-18 Citigroup maintain Buy $371.00
2026-02-18 Chardan Capital maintain Buy $323.00
2026-02-17 Jefferies maintain Buy $371.00
2026-02-02 Goldman Sachs maintain Buy $327.00
2026-01-22 B of A Securities maintain Buy $318.00
2026-01-12 Citigroup maintain Buy $336.00
2026-01-09 TD Cowen maintain Buy $306.00
2026-01-09 Citigroup maintain Buy $320.00

Over the past 30 days, there has been 1 upgrade and 0 downgrades. EPS revisions show slight downward pressure: current-year EPS estimate is $7.73, down from $7.86 one month ago, with 1 upward and 1 downward revision in the past 30 days. Quarterly EPS for next quarter is $1.75, up slightly from $1.68 a month ago, but revisions are flat (0 up, 1 down in 30 days).

Firm Track Record — Citigroup

Citigroup accuracy: 55% on 4355 calls | avg return: 4.9%

Industry benchmark: mean 51% ± 11%. Top tier: ≥61% (mean + 1σ). Based on 6 firms with ≥5 scored calls.

FirmAccuracyCallsAvg Returnvs Average
B of A Securities 100% 2/2 36.3% top tier
Chardan Capital 67% 6/9 15.1% top tier
Citigroup 57% 4/7 11.7% above average
HC Wainwright & Co. 53% 10/19 6.9% above average
Cantor Fitzgerald 50% 1/2 -13.4% below average
Stifel 50% 1/2 8.4% below average

Citigroup has a 57% accuracy rate (4 correct out of 7 scored calls) and an average return of 11.7% on rated stocks, placing it above average compared to other firms covering KRYS. B of A Securities leads with 100% accuracy (2/2), followed by Chardan Capital (67% on 9), while Cantor and Stifel lag at 50%. Citigroup’s track record supports moderate confidence in this call.

Earnings Estimates

PeriodEPS Est.EPS RangeRevenueRevisions (7d)
0y $7.73 $5.57 — $9.59 $537.6M ↑0 ↓0
0q $1.47 $1.28 — $1.79 $112.8M ↑0 ↓0
+1y $10.58 $6.52 — $20.30 $691.4M ↑0 ↓0
+1q $1.75 $1.37 — $2.08 $127.1M ↑0 ↓0

Cross-Platform Signals

Insider Trades (90d)
0 buys / 5 sells
Institutional
BANK OF AMERICA CORP /DE/ — add (38.3%)
Institutional
WELLS FARGO & COMPANY/MN — add (60.6%)
Institutional
NORGES BANK — new

Insiders have been net sellers: $2.9M in sales over the past month, including $2.6M by Daniel Janney and $124K by Krishnan S. This contrasts with strong institutional inflows: Norges Bank initiated a $70.2M position, UBS added $49.2M (+86.5%), and BofA added $47M (+38.3%). Renaissance Technologies also initiated a new $814K stake. This divergence suggests institutions are accumulating while insiders take profits.

Actionable Insight

Buy the upgrade — Citigroup’s call aligns with institutional accumulation despite insider selling. The $309 target is achievable near-term given the $314 mean PT and strong buy-side consensus. Monitor for next earnings catalyst.

Documents Analyzed

Report based on filing metadata.

8 reports for KRYS
Performance horizon

Track record builds as more directional reports settle.

Filters
Rows
Reports for KRYS — sortable, filterable
Type Now
Jun 5, 2026
1d ago
Insider Cluster
NEUTRAL ★ 2/10
awaiting T+20
May 16, 2026
21d ago
ANALYST-UPGRADE
BULLISH ★ 5/10
$249.39 $269.13▲ +7.92%▲ +9.01%$301.00 (+20.69%)
May 4, 2026
4w ago
Press Release
BULLISH ★ 6/10
$286.95 $298.10▲ +3.89%▼ −1.76%$301.00 (+4.90%)
Apr 21, 2026
6w ago
Press Release
NEUTRAL ★ 3/10
$272.66 $291.75▲ +7.00%▲ +2.09%$301.00 (+10.39%)
Apr 16, 2026
7w ago
ANALYST-UPGRADE
BULLISH ★ 4/10
$274.21 $316.30▲ +15.35%▲ +9.98%$301.00 (+9.77%)
Apr 3, 2026
9w ago
DEFA14A
NEUTRAL ★ 2/10
$261.80 $286.95▲ +9.61%▲ +0.62%$301.00 (+14.97%)
Feb 27, 2026
14w ago
Insider Cluster
NEUTRAL ★ 3/10
$275.64 $245.39▼ −10.97%▼ −3.42%$301.00 (+9.20%)
Feb 27, 2026
14w ago
Insider Cluster
NEUTRAL ★ 5/10
$275.64 $245.39▼ −10.97%▼ −3.42%$301.00 (+9.20%)
Showing 8 of 8

US Market Status

Market Closed — Opens Mon (12h 13m)

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