HRTX HERON THERAPEUTICS, INC. /DE/

BEARISH Impact: 7/10 8-K
Horizon weeks Filed Jun 2, 2026 Processed 4d 1h ago SEC 0001193125-26-253851
8-K context-dependent: Items 8.01
Latest settled — T+1d
HRTX ▲ +7.44% at T+1d
SHORT call ✗ call lost -7.44% · α vs SPY -7.04% · entry $0.4500 → $0.4835
Next anchor: T+5d in 3d
Currently $0.4300 · +4.44% from $0.4500 entry (call sign-flipped)
Entry anchored
Jun 2, 03:59 PM ET
via Databento tick
T+1d
+7.44%
call -7.44% · α -7.04%
$0.4835
settled 3d ago
T+5d
call — · α —
in 3d
T+20d
call — · α —
in 25d
T+60d
call — · α —
in 3mo

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Executive Summary

The U.S. District Court for the District of Delaware held that the asserted claims of Heron's CINVANTI patents (U.S. Patent Nos. 12,115,255 and 12,290,520) are invalid, removing patent protection for its anti-nausea drug CINVANTI against a generic challenger (Azurity/Slayback). Heron intends to appeal to the Federal Circuit, but the ruling opens the door to near-term generic competition absent a successful appeal or stay.

Actionable Insight

The invalidation of CINVANTI patents is a material negative catalyst. Monitor Heron's appeal to the Federal Circuit — a stay of generic entry pending appeal is possible but not guaranteed. Expect significant downside pressure on HRTX shares as the market prices in generic competition risk.

Key Facts

  • District Court held asserted claims of U.S. Patent Nos. 12,115,255 and 12,290,520 invalid on June 1, 2026.
  • Ruling covers CINVANTI (aprepitant) injectable emulsion, a key commercial product for Heron.
  • Heron intends to appeal to the U.S. Court of Appeals for the Federal Circuit.
  • Decision does not affect prior settlement agreements related to CINVANTI or APONVIE.
  • No financial figures (revenue, market size, damages) were disclosed in the filing.

Financial Impact

CINVANTI is a commercial product; loss of patent exclusivity threatens material revenue erosion. No specific revenue or market size figures provided in the filing.

revenue

Risk Factors

  • Generic entry by Azurity/Slayback could begin immediately if no stay is granted, severely impacting CINVANTI sales.
  • Appeal to the Federal Circuit may take 12-18 months; outcome uncertain.
  • Heron's remaining pipeline and other products may not offset CINVANTI revenue loss.

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
89% bullish (9 analysts)

Documents Analyzed

This report is based on 5 SEC documents filed with EDGAR.

DocumentAccession Number
8-K Filing (Primary)0001193125-26-253851
Document: hrtx-ex99_1.htm0001193125-26-253851
Document: 0001193125-26-253851-index-headers.html0001193125-26-253851
Document: 0001193125-26-253851-index.html0001193125-26-253851
Document: 0001193125-26-253851.txt0001193125-26-253851
7 reports for HRTX
Performance horizon

Track record builds as more directional reports settle.

Filters
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Reports for HRTX — sortable, filterable
Type Now
Jun 2, 2026
4d ago
8-K
BEARISH ★ 7/10
$0.4500 $0.4835▼ −7.44%▼ −7.04%$0.4300 (+4.44%)
May 11, 2026
26d ago
8-K
BEARISH ★ 6/10
$0.9600 $0.9600· 0.00%▼ −0.14%$0.4300 (+55.21%)
May 11, 2026
26d ago
Press Release
BEARISH ★ 6/10
$0.9600 $0.9600· 0.00%▼ −0.14%$0.4300 (+55.21%)
Apr 30, 2026
5w ago
DEFA14A
NEUTRAL ★ 2/10
$1.20 $1.27▲ +5.83%▲ +5.61%$0.4300 (−64.17%)
Apr 27, 2026
5w ago
Press Release
NEUTRAL ★ 1/10
$1.21 $1.17▼ −3.72%▼ −3.71%$0.4300 (−64.46%)
Apr 6, 2026
8w ago
8-K
NEUTRAL ★ 4/10
$0.8100 $0.7900▼ −2.47%▼ −2.53%$0.4300 (−46.91%)
Feb 26, 2026
14w ago
8-K
MIXED ★ 6/10
$1.20 $1.19▼ −0.83%▼ −0.38%$0.4300 (−64.17%)
Showing 7 of 7

US Market Status

Market Closed — Opens Mon (14h 48m)

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