AXSM Axsome Therapeutics, Inc.

NEUTRAL Impact: 4/10 Insider Cluster (3 insiders)
Horizon weeks Filed Jun 11, 2026 Processed 2d 13h ago
Insider cluster: 3 insiders, $20.1M total

Price Chart

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Executive Summary

CEO Herriot Tabuteau and CFO Nick Pizzie sold a combined ~$19.9M in open-market sales on June 9, 2026, following derivative exercises. Director Mark Coleman also sold $160K. The total open-market sales of ~$20.05M represent ~0.16% of AXSM's $12.6B market cap — a modest but notable cluster. The CEO and CFO selling simultaneously after exercising options is a common liquidity-driven pattern (cashless exercise-to-sell), not a bearish signal. The cluster is amplified by the historical calibration (AMPLIFIER verdicts for cluster-insider-trades + multiple contexts), but the proportionality check and academic literature on cluster sales being non-informative keep the impact moderate.

Key Financial Metrics

Direction
selling
Total Value
$20.1M
Insiders
3

Actionable Insight

The CEO and CFO selling simultaneously after option exercises is a routine cashless exercise pattern, not a bearish signal. Monitor next 10-Q for any fundamental deterioration, but this cluster alone does not warrant action. The historical win rate on AXSM reports is 88% at T+20, suggesting the stock tends to drift higher — this sale cluster is unlikely to reverse that trend.

Key Facts

  • CEO Herriot Tabuteau sold 49,670 shares at $241.01 for ~$11.97M on June 9, 2026
  • CFO Nick Pizzie sold 33,000 shares at $240.09 for ~$7.92M on June 9, 2026
  • Both CEO and CFO exercised derivatives immediately prior to sales (cashless exercise-to-sell pattern)
  • Director Mark Coleman sold 643 shares at $249 for $160K on June 10, 2026
  • Total open-market sales: ~$20.05M, representing ~0.16% of AXSM's $12.6B market cap
  • No open-market purchases in the cluster; all non-cash transactions (grants, awards, derivative exercises) have $0 economic value
  • Historical calibration shows this cluster is an AMPLIFIER for insider-trades contexts, but the proportionality band (0.1-0.5%) suggests modest impact

Financial Impact

Total open-market sales of ~$20.05M, ~0.16% of market cap — modest relative to company size

dilutioninsider ownership

Risk Factors

  • Insider sales could signal management's view of near-term headwinds, though the cashless exercise pattern mitigates this
  • Further insider selling in coming weeks would increase bearish weight
  • Stock is near all-time highs (~$246) — profit-taking by insiders is natural

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
93% bullish (27 analysts)

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CLUSTER Data (Synthetic)cluster-AXSM-1781142574601
15 reports for AXSM
Performance horizon
75% Hit rate 3 of 4 directional calls best @ T+20▲ +12.07%Apr 30, 2026
Filters
Rows
Reports for AXSM — sortable, filterable
Type Now
Jun 12, 2026
1d ago
Insider Cluster
NEUTRAL ★ 4/10
$253.88 awaiting T+1awaiting T+1$255.17 (+0.51%)
Jun 11, 2026
1d ago
144
NEUTRAL ★ 1/10
$253.88 awaiting T+1awaiting T+1$255.17 (+0.51%)
Jun 11, 2026
2d ago
Insider Cluster
NEUTRAL ★ 4/10
$246.42 awaiting T+1awaiting T+1$255.17 (+3.55%)
Jun 9, 2026
3d ago
144
NEUTRAL ★ 4/10
$245.68 awaiting T+1awaiting T+1$255.17 (+3.86%)
Jun 9, 2026
3d ago
8-K
NEUTRAL ★ 2/10
$245.68 awaiting T+1awaiting T+1$255.17 (+3.86%)
Jun 9, 2026
3d ago
Insider Cluster
NEUTRAL ★ 4/10
$245.68 awaiting T+1awaiting T+1$255.17 (+3.86%)
Jun 4, 2026
9d ago
Press Release
NEUTRAL ★ 3/10
$231.48 $232.32▲ +0.36%▲ +2.96%$255.17 (+10.23%)
Jun 3, 2026
10d ago
8-K
BULLISH ★ 7/10
$233.49 $231.48▼ −0.86%▼ −1.26%$255.17 (+9.29%)
May 4, 2026
5w ago
8-K
MIXED ★ 6/10
$223.70 $223.06▼ −0.29%▼ −1.08%$255.17 (+14.07%)
May 4, 2026
5w ago
Press Release
MIXED ★ 6/10
$223.70 $223.06▼ −0.29%▼ −1.08%$255.17 (+14.07%)
Showing 10 of 15

US Market Status

Market Closed — Opens Mon (45h 44m)

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