ANAB ANAPTYSBIO, INC

BEARISH Impact: 5/10 144
Horizon days Filed May 22, 2026 Processed 7d 17h ago SEC 0001950047-26-004947
Form 144 — notice of proposed sale of securities
Latest settled — T+5d
ANAB ▼ -11.27% at T+5d
SHORT call ✓ call won +11.27% · α vs SPY +12.48% · entry $57.77 → $51.26
Next anchor: T+20d in 10d
Currently $56.07 · +2.94% from $57.77 entry (call sign-flipped)
Entry anchored
May 22, 03:59 PM ET
via Databento tick
T+1d
-0.14%
call +0.14% · α +0.15%
$57.69
settled 18d ago
T+5d
-11.27%
call +11.27% · α +12.48%
$51.26
settled 12d ago
T+20d
call — · α —
in 10d
T+60d
call — · α —
in 2mo

Price Chart

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Executive Summary

Dennis Mulroy, an officer of AnaptysBio, filed a Form 144 notice of intent to sell 10,000 shares of common stock, valued at approximately $593,008 based on the filing date price. This follows three prior sales in the same week totaling 35,467 shares for ~$2.16M, indicating a concentrated selling pattern by an insider.

Actionable Insight

This is the fourth insider sale filing from the same officer within one week, signaling a routine option-exercise/cash-out cycle but at an elevated frequency. For a $1.5B biotech with no disclosed near-term catalyst, the concentrated selling is a modest negative signal. Historical reports on ANAB have shown poor T+20 performance (avg -9.4%), suggesting caution. Monitor for additional Form 4 filings or a material change in corporate outlook that could explain the selling.

Key Facts

  • Form 144 filed on 2026-05-22 by officer Dennis Mulroy
  • Proposed sale of 10,000 shares of common stock
  • Estimated value: ~$593,008 at market price on filing date
  • Shares acquired via stock option exercise on 05/22/2026 for cash
  • Three prior open-market sales by Mulroy in the preceding week: 15,467 shares on 05/21 ($928k), 10,000 on 05/19 ($599k), 10,000 on 05/15 ($633k)
  • Cumulative insider sales by Mulroy in the past week: ~45,467 shares for ~$2.75M

Financial Impact

Proposed additional sale of ~$593k; combined week of insider selling totals ~$2.75M against a $1.5B market cap

dilutioninsider ownership

Risk Factors

  • Insider selling may indicate lack of confidence in near-term share appreciation
  • Historical T+20 performance on ANAB filings has been negative across several prior reads
  • Biotech sector volatility could amplify any negative sentiment from insider sales

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
94% bullish (17 analysts)

Documents Analyzed

This report is based on 3 SEC documents filed with EDGAR.

DocumentAccession Number
144 Filing (Primary)0001950047-26-004947
Document: 0001950047-26-004947-index.html0001950047-26-004947
Document: 0001950047-26-004947.txt0001950047-26-004947
17 reports for ANAB
Performance horizon
86% Hit rate 6 of 7 directional calls best @ T+60▲ +41.26%Mar 3, 2026
Filters
Rows
Reports for ANAB — sortable, filterable
Type Now
Jun 11, 2026
1d ago
144
BEARISH ★ 6/10
$54.24 awaiting T+1awaiting T+1$56.07 (−3.38%)
Jun 10, 2026
2d ago
144
BEARISH ★ 5/10
$51.96 awaiting T+1awaiting T+1$56.07 (−7.91%)
Jun 8, 2026
4d ago
144
BEARISH ★ 5/10
$51.38 awaiting T+1awaiting T+1$56.07 (−9.14%)
Jun 5, 2026
7d ago
144
BEARISH ★ 5/10
$50.58 awaiting T+1awaiting T+1$56.07 (−10.85%)
Jun 5, 2026
7d ago
144
BEARISH ★ 5/10
$51.33 awaiting T+1awaiting T+1$56.07 (−9.23%)
Jun 3, 2026
9d ago
144
BEARISH ★ 5/10
$51.67 $50.37▲ +2.52%▼ −0.08%$56.07 (−8.52%)
Jun 1, 2026
11d ago
144
BEARISH ★ 5/10
$51.26 $51.24▲ +0.04%▼ −0.68%$56.07 (−9.38%)
May 29, 2026
14d ago
8-K
NEUTRAL ★ 2/10
$53.14 $51.26▼ −3.54%▼ −3.69%$56.07 (+5.51%)
May 28, 2026
15d ago
144
NEUTRAL ★ 3/10
$55.67 $53.14▼ −4.54%▼ −4.80%$56.07 (+0.72%)
May 27, 2026
16d ago
144
BEARISH ★ 6/10
$57.02 $55.67▲ +2.37%▲ +2.61%$56.07 (+1.67%)
Showing 10 of 17

US Market Status

Market Closed — Opens Mon (52h 18m)

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