ANAB ANAPTYSBIO, INC

BEARISH Impact: 6/10 144
Horizon weeks Filed Jun 11, 2026 Processed 3d 13h ago SEC 0001950047-26-005960
Form 144 — notice of proposed sale of securities

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Executive Summary

Dennis Mulroy, an officer of AnaptysBio, filed a Form 144 notice of intent to sell 35,000 common shares valued at approximately $1.85 million, to be executed through Morgan Stanley. The filing also reveals a heavy pattern of insider selling: Mulroy has sold over 260,000 shares in the past three weeks (May 15–June 10), totaling about $13.4 million, all via open-market sales after stock option exercises. This sustained selling by a top officer ahead of any public catalyst is a significant bearish signal.

Actionable Insight

The sustained insider selling by a top officer at a rate of ~$1M/week is a strong negative signal, especially given the stock's high valuation and bullish analyst consensus. Traders should consider reducing exposure or hedging ahead of potential negative catalysts (e.g., clinical data, earnings). Monitor for Form 4 filings to confirm actual sales and watch for any material news that could explain the selling.

Key Facts

  • Officer Dennis Mulroy filed Form 144 to sell 35,000 shares (~$1.85M) on June 11, 2026.
  • The filing reveals 18 prior open-market sales between May 15 and June 10, 2026, totaling ~260,000 shares and ~$13.4M.
  • All sales were executed after stock option exercises, indicating a systematic plan to monetize equity.
  • AnaptysBio has a $1.5B market cap and 94% analyst bullish consensus, making the insider selling pattern particularly notable.
  • Historical calibration shows score-6 filings in this segment have a 34% observed probability of up-move at T+20, with a net negative average alpha.

Financial Impact

Officer sold ~$13.4M in shares over 3 weeks, with an additional $1.85M proposed; total ~$15.3M in planned sales.

insider selling volumedilution from option exercises

Risk Factors

  • Insider selling may indicate undisclosed negative developments (e.g., clinical trial setbacks, regulatory delays).
  • Heavy option exercise and sale pattern could pressure the stock if selling continues.
  • The 144 filing is an intent to sell; if the insider does not execute, the signal may be less severe.

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
94% bullish (17 analysts)

Documents Analyzed

This report is based on 3 SEC documents filed with EDGAR.

DocumentAccession Number
144 Filing (Primary)0001950047-26-005960
Document: 0001950047-26-005960-index.html0001950047-26-005960
Document: 0001950047-26-005960.txt0001950047-26-005960
17 reports for ANAB
Performance horizon
88% Hit rate 7 of 8 directional calls best @ T+60▲ +41.26%Mar 3, 2026
Filters
Rows
Reports for ANAB — sortable, filterable
Type Now
Jun 11, 2026
3d ago
144
BEARISH ★ 6/10
$54.24 awaiting T+1awaiting T+1$56.07 (−3.38%)
Jun 10, 2026
4d ago
144
BEARISH ★ 5/10
$51.96 awaiting T+1awaiting T+1$56.07 (−7.91%)
Jun 8, 2026
6d ago
144
BEARISH ★ 5/10
$51.38 awaiting T+1awaiting T+1$56.07 (−9.14%)
Jun 5, 2026
9d ago
144
BEARISH ★ 5/10
$50.58 awaiting T+1awaiting T+1$56.07 (−10.85%)
Jun 5, 2026
9d ago
144
BEARISH ★ 5/10
$51.33 awaiting T+1awaiting T+1$56.07 (−9.23%)
Jun 3, 2026
11d ago
144
BEARISH ★ 5/10
$51.67 $50.37▲ +2.52%▼ −0.08%$56.07 (−8.52%)
Jun 1, 2026
13d ago
144
BEARISH ★ 5/10
$51.26 $51.24▲ +0.04%▼ −0.68%$56.07 (−9.38%)
May 29, 2026
16d ago
8-K
NEUTRAL ★ 2/10
$53.14 $51.26▼ −3.54%▼ −3.69%$56.07 (+5.51%)
May 28, 2026
17d ago
144
NEUTRAL ★ 3/10
$55.67 $53.14▼ −4.54%▼ −4.80%$56.07 (+0.72%)
May 27, 2026
18d ago
144
BEARISH ★ 6/10
$57.02 $55.67▲ +2.37%▲ +2.61%$56.07 (+1.67%)
Showing 10 of 17

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